{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:20:57Z","timestamp":1744258857621,"version":"3.40.4"},"reference-count":0,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"2","license":[{"start":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T00:00:00Z","timestamp":1560470400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Background: Furosemide is the most commonly prescribed loop diuretic worldwide. Although, its extended use, furosemide rarely induces allergic reactions. Until 2013, only 49 cases of furosemide allergy had been described.Clinical case: We have reported on a patient who developed a delayed, erythematous and pruritic skin eruption after the ingestion of furosemide. The implication of furosemide in the reaction was established by a positive lymphocyte transformation test (LTT).Conclusion: This is the first reported case of hypersensitivity to furosemide in which this drug was confirmed as the trigger by a positive LTT. LTT could become a decent diagnostic alternative for patients who experience delayed reactions to furosemide.\u00a0<\/jats:p>","DOI":"10.29262\/ram.v66i2.371","type":"journal-article","created":{"date-parts":[[2019,6,15]],"date-time":"2019-06-15T00:10:51Z","timestamp":1560557451000},"page":"254-256","source":"Crossref","is-referenced-by-count":1,"title":["Delayed allergic reaction to furosemide with a positive lymphocyte transformation test","Reacci\u00f3n al\u00e9rgica tard\u00eda a furosemida con positividad de la prueba de transformaci\u00f3n de linfocitos"],"prefix":"10.29262","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6195-417X","authenticated-orcid":false,"given":"Olga Patricia","family":"Monge-Ortega","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5397-2327","authenticated-orcid":false,"given":"Javier","family":"Dom\u00ednguez-Ortega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3957-4955","authenticated-orcid":false,"given":"Miguel","family":"Gonz\u00e1lez-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8601-1728","authenticated-orcid":false,"given":"Rosario","family":"Caba\u00f1as","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5815-5211","authenticated-orcid":false,"given":"Mar\u00eda Magdalena","family":"Lluch-Bernal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0446-9562","authenticated-orcid":false,"given":"Ana","family":"Fiandor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4919-5166","authenticated-orcid":false,"given":"Luz Yadira","family":"Bravo-Gallego","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8086-0921","authenticated-orcid":false,"given":"Santiago","family":"Quirce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2019,6,14]]},"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/371\/2446","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/371\/1039","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/371\/1008","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/371\/2446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T16:02:22Z","timestamp":1744214542000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,14]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,6,14]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v66i2.371","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"type":"electronic","value":"2448-9190"},{"type":"print","value":"0002-5151"}],"subject":[],"published":{"date-parts":[[2019,6,14]]}}}