{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:16:21Z","timestamp":1740179781856,"version":"3.37.3"},"reference-count":0,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"3","license":[{"start":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T00:00:00Z","timestamp":1560902400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["RAM"],"abstract":"<jats:p>Antecedentes: La hipoplasia cart\u00edlago-cabello es una enfermedad autos\u00f3mica recesiva poco frecuente, caracterizada por condrodisplasia metafisaria y cabello fino. Puede estar acompa\u00f1ada de alteraciones inmunol\u00f3gicas en distintos grados.Caso cl\u00ednico: Ni\u00f1a de 35 meses de edad, quien desde su nacimiento mostr\u00f3 restricci\u00f3n del crecimiento; desarroll\u00f3 11 cuadros de neumon\u00edas, s\u00edndrome de malabsorci\u00f3n y megacolon agangli\u00f3nico, por lo que se diagnostic\u00f3 hipoplasia cart\u00edlago-cabello, con expresi\u00f3n de inmunodeficiencia combinada no severa. Se decidi\u00f3 trasplante de c\u00e9lulas madre hematopoy\u00e9ticas. Al momento de este informe, la paciente estaba libre de procesos infecciosos.Conclusi\u00f3n: La hipoplasia cart\u00edlago-cabello es un padecimiento con rasgos cl\u00ednicos y distintos grados de inmunodeficiencia. Como parte del tratamiento es posible realizar trasplante de c\u00e9lulas madre hematopoy\u00e9ticas.<\/jats:p>","DOI":"10.29262\/ram.v66i3.561","type":"journal-article","created":{"date-parts":[[2019,10,12]],"date-time":"2019-10-12T02:20:16Z","timestamp":1570846816000},"page":"379-383","source":"Crossref","is-referenced-by-count":0,"title":["Hipoplasia cart\u00edlago-cabello. Reporte de un caso"],"prefix":"10.29262","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0776-8162","authenticated-orcid":false,"given":"Tamara Aid\u00e9","family":"Staines-Boones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5521-2340","authenticated-orcid":false,"given":"Mar\u00eda Guadalupe","family":"Gonz\u00e1lez-Villarreal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3818-1129","authenticated-orcid":false,"given":"Cecilia","family":"Hern\u00e1ndez-Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2019,6,19]]},"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/561\/1064","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/561\/1136","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/561\/1085","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/561\/1064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T20:57:30Z","timestamp":1627678650000},"score":1,"resource":{"primary":{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,19]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,10,7]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v66i3.561","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"type":"electronic","value":"2448-9190"},{"type":"print","value":"0002-5151"}],"subject":[],"published":{"date-parts":[[2019,6,19]]}}}