{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:16:24Z","timestamp":1740179784974,"version":"3.37.3"},"reference-count":0,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"1","license":[{"start":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T00:00:00Z","timestamp":1589760000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["RAM"],"abstract":"<jats:p>Antecedentes: En su mayor\u00eda, las reacciones adversas por inmunoterapia espec\u00edfica subcut\u00e1nea de al\u00e9rgenos est\u00e1n directamente inducidas por la administraci\u00f3n del al\u00e9rgeno; por lo general se presenta enrojecimiento e induraci\u00f3n de la zona de inyecci\u00f3n y otras lesiones cut\u00e1neas son raras.Caso cl\u00ednico: Mujer de 40 a\u00f1os, con rinoconjuntivitis al\u00e9rgica y asma por sensibilizaci\u00f3n al polen de gram\u00edneas, quien recib\u00eda mensualmente 0.5\u00a0mL de un extracto polimerizado subcut\u00e1neo de polen de gram\u00edneas, con glutaraldeh\u00eddo y adsorbido en hidr\u00f3xido de aluminio. Cinco horas despu\u00e9s de la administraci\u00f3n de la s\u00e9ptima dosis, la paciente present\u00f3 ardor y prurito en la zona de la inyecci\u00f3n de la inmunoterapia y, posteriormente, ampollas.Conclusiones: Aunque las reacciones adversas por inmunoterapia espec\u00edfica de al\u00e9rgenos son raras y dif\u00edciles de demostrar, es importante realizar los an\u00e1lisis que se requieran para identificar las causas o su relaci\u00f3n con los s\u00edntomas a fin de evitar reacciones futuras.<\/jats:p>","DOI":"10.29262\/ram.v67i1.671","type":"journal-article","created":{"date-parts":[[2020,5,25]],"date-time":"2020-05-25T03:14:51Z","timestamp":1590376491000},"page":"83-86","source":"Crossref","is-referenced-by-count":1,"title":["Reacci\u00f3n tipo penfigoide por inmunoterapia  al\u00e9rgeno-espec\u00edfica: una reacci\u00f3n adversa inusual"],"prefix":"10.29262","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6816-3880","authenticated-orcid":false,"given":"Margarita","family":"Tom\u00e1s-P\u00e9rez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5397-2327","authenticated-orcid":false,"given":"Javier","family":"Dom\u00ednguez-Ortega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2020,5,18]]},"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/671\/1161","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/671\/1252","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/671\/1186","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/671\/1161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T20:42:29Z","timestamp":1627677749000},"score":1,"resource":{"primary":{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,18]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,4,29]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v67i1.671","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"type":"electronic","value":"2448-9190"},{"type":"print","value":"0002-5151"}],"subject":[],"published":{"date-parts":[[2020,5,18]]}}}