{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T08:25:42Z","timestamp":1745569542718,"version":"3.40.4"},"reference-count":20,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"3","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Objective: To determine the prevalence of blood eosinophilia in adults with chronic obstructive pulmonary disease (COPD) according to different cut-off points.\nMethods: A cross-sectional study was carried out in patients with COPD. The frequency of blood eosinophilia was determined by absolute (cells\/ \u00b5L) and relative (%) eosinophil count. Multivariate methods were used in order to identify the associated factors.\nResults: 81 patients were included; the mean age was 71.9 \u00b1 9.8 years; 46 (57%) of the patients were men. The prevalence of eosinophilia for the cut-off points of \u2265 100, \u2265 150, \u2265 200, \u2265 300, and \u2265 400 cells\/\u00b5L was of 64.2%, 37.0%, 16.1%, and 9.9% respectively. Out of 81 patients, 34 (42%) had a relative eosinophil concentration of \u2265 2%; 21 (25.9%) \u2265 3%; 14 patients (17.3%) had \u2265 4%; and 10 patients (12.3%) had \u2265 5%. Eosinophilia of \u2265 100 cells\/\u00b5L was associated with age of \u2265 80 years (OR = 6.04, p = 0.026), and with the exacerbation of COPD (OR = 9.40, p = 0.038); in contrast, eosinophilia of \u2265 2% was associated only with age of \u2265 80 years (OR = 3.73, p = 0.020). In addition, the eosinophil count of \u2265 100 and &lt; 300 cells\/\u00b5L was associated with the exacerbation of COPD (OR = 11.00, p = 0.026). \nConclusions: Our results suggest that the frequency of eosinophilia in the context of COPD shows substantial variations according to the used definition.<\/jats:p>","DOI":"10.29262\/ram.v67i3.893","type":"journal-article","created":{"date-parts":[[2021,9,19]],"date-time":"2021-09-19T20:49:39Z","timestamp":1632084579000},"page":"152-159","source":"Crossref","is-referenced-by-count":2,"title":["Prevalencia de eosinofilia en sangre en adultos con EPOC seg\u00fan el punto de corte","Prevalence of blood eosinophilia in adults with COPD according to the cut-off point"],"prefix":"10.29262","volume":"68","author":[{"given":"Mart\u00edn","family":"Bedolla-Barajas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaime","family":"Morales-Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tonantzin Isis","family":"Bedolla-Pulido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam Montzerrat","family":"Flores-Razo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2131-5485","authenticated-orcid":false,"given":"Marco Antonio","family":"Morales-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8275-8004","authenticated-orcid":false,"given":"Gustavo","family":"Rosales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4243-497X","authenticated-orcid":false,"given":"Kevin Javier","family":"Arellano Arteaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7462-3196","authenticated-orcid":false,"given":"Beatriz Alejandra","family":"Paz-Velarde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Biener AI, Decker SL, Rohde F. 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