{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:16:27Z","timestamp":1740179787619,"version":"3.37.3"},"reference-count":27,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"1","license":[{"start":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T00:00:00Z","timestamp":1623024000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Antecedentes: El impacto de la obesidad sobre la gravedad del asma conti\u00faa siendo motivo de controversia. Objetivo: Comparar la gravedad y el control del asma entre pacientes con obesidad y sin obesidad. M\u00e9todos: Estudio transversal que incluy\u00f3 a 188 pacientes con asma, con edad \u2265 18 a\u00f1os, seleccionados consecutivamente. Los pacientes fueron categorizados y comparados de acuerdo con la presencia de obesidad o no. Para establecer asociaci\u00f3n entre variables se realiz\u00f3 an\u00e1lisis de regresi\u00f3n log\u00edstica. Resultados: En total, 111 pacientes ten\u00edan obesidad; su edad fue mayor que la de los pacientes sin obesidad (35.9 \u00b1 15.3 a\u00f1os versus 44.4 \u00b1 13.8 a\u00f1os, p &lt; 0.001). No se observ\u00f3 diferencia significativa entre los grupos respecto a sexo, concentraci\u00f3n s\u00e9rica total de IgE, n\u00famero de eosin\u00f3filos en sangre perif\u00e9rica, historia personal de enfermedad at\u00f3pica, frecuencia de sensibilizaci\u00f3n al\u00e9rgica, hospitalizaci\u00f3n por asma y control del asma. En general, la obesidad se asoci\u00f3 significativamente con el asma moderada o grave (RM = 1.82, p = 0.047), pero no lo hizo con el control del asma (p = 0.094). Conclusiones: Nuestros resultados sugieren que los pacientes con asma y obesidad tienen mayor edad y peor funci\u00f3n pulmonar, la cual se reflejada en mayor gravedad del asma.<\/jats:p>","DOI":"10.29262\/ram.v68i1.756","type":"journal-article","created":{"date-parts":[[2021,6,21]],"date-time":"2021-06-21T01:02:29Z","timestamp":1624237349000},"page":"26-34","source":"Crossref","is-referenced-by-count":1,"title":["La obesidad en adultos est\u00e1 asociada con la gravedad del asma, pero no con el control del asma"],"prefix":"10.29262","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4915-1582","authenticated-orcid":false,"given":"Mart\u00edn","family":"Bedolla-Barajas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1492-1797","authenticated-orcid":false,"given":"Jaime","family":"Morales-Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3419-5160","authenticated-orcid":false,"given":"Juan Carlos","family":"L\u00f3pez-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5292-0728","authenticated-orcid":false,"given":"Tonatiuh Ramses","family":"Bedolla-Pulido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8513-1613","authenticated-orcid":false,"given":"Lourdes Fabiola","family":"Garc\u00eda-Padilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2479-3773","authenticated-orcid":false,"given":"Miriam Montzerrat","family":"Flores-Razo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2021,6,7]]},"reference":[{"key":"ref0","unstructured":"Delgado J, Barranco P, Quirce S. 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