{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T14:49:30Z","timestamp":1766587770725,"version":"3.40.5"},"reference-count":18,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"3","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["RAM"],"abstract":"<jats:p>Objetivos: El objetivo primario de este estudio fue definir la relaci\u00f3n entre los niveles de vitamina D y las interleucinas (IL) 1\u03b2 y 6, como marcadores inflamatorios en poblaci\u00f3n sana. Como objetivo secundario, medir la prevalencia de insuficiencia\/deficiencia de vitamina D en la misma poblaci\u00f3n.\nM\u00e9todos: Se seleccion\u00f3 una muestra de 43 donadores de sangre sanos, sin enfermedades cr\u00f3nico-degenerativas, inflamatorias o infecciosas, y sin obesidad. A los individuos con insuficiencia o deficiencia de vitamina D se les midieron niveles s\u00e9ricos de IL-1\u03b2 e IL-6. Se midi\u00f3 la correlaci\u00f3n de vitamina D e interleucinas mediante rho de Spearman.\nResultados: No se encontr\u00f3 correlaci\u00f3n entre los niveles de vitamina D y las interleucinas. Adicionalmente, se encontr\u00f3 una prevalencia de insuficiencia\/deficiencia de vitamina D en 95.3\u00a0% de la muestra.\nConclusiones: En sujetos sanos con deficiencia o insuficiencia de vitamina D, no existe correlaci\u00f3n entre los niveles de esta vitamina y de IL-1\u03b2 e IL-6.<\/jats:p>","DOI":"10.29262\/ram.v68i3.885","type":"journal-article","created":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T23:21:28Z","timestamp":1634080888000},"page":"180-184","source":"Crossref","is-referenced-by-count":1,"title":["Correlaci\u00f3n entre la insuficiencia o deficiencia de los niveles de vitamina D  y las interleucinas 1\u03b2 y 6"],"prefix":"10.29262","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6405-7810","authenticated-orcid":false,"given":"Luis Fernando","family":"Zavala-Jonguitud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0290-2078","authenticated-orcid":false,"given":"Juan Carlos","family":"Anda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0697-620X","authenticated-orcid":false,"given":"Miguel Guillermo","family":"Flores-Padilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0956-2096","authenticated-orcid":false,"given":"Carla","family":"P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6462-8935","authenticated-orcid":false,"given":"Jos\u00e9 Daniel","family":"Ju\u00e1rez-Villa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Holick MF. 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