{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T01:56:30Z","timestamp":1748397390105,"version":"3.37.3"},"reference-count":16,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"3","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["RAM"],"abstract":"<jats:p>Introducci\u00f3n: El s\u00edndrome de Heiner es una enfermedad pulmonar muy rara, pero reversible, debida a una hipersensibilidad no mediada por IgE a las prote\u00ednas de la leche de vaca resultando en una enfermedad pulmonar at\u00edpica en beb\u00e9s y lactantes. Se han reportado muy pocos casos. Debido a sus manifestaciones heterog\u00e9neas, el diagn\u00f3stico puede retrasarse, ya que puede cursar con infecciones respiratorias cr\u00f3nicas o recurrentes de v\u00eda a\u00e9rea alta o baja, fiebre, falla en el crecimiento o s\u00edntomas gastrointestinales. Los infiltrados pulmonares pueden ser confundidos con neumon\u00eda, pero el s\u00edndrome de Heiner es refractario al tratamiento con antibi\u00f3ticos.\nReporte de caso: Describimos el caso de un neonato de un mes cuyo s\u00edntoma principal fue hematemesis, que es un s\u00edntoma muy raro. El diagn\u00f3stico se confirm\u00f3 con la remisi\u00f3n total de los s\u00edntomas al suprimir de forma estricta la leche y sus derivados.\nConclusiones: El pron\u00f3stico es favorable si se instaura una dieta libre de l\u00e1cteos tempranamente. La mayor\u00eda de los ni\u00f1os tolerar\u00e1n la leche en pocos a\u00f1os.<\/jats:p>","DOI":"10.29262\/ram.v68i3.901","type":"journal-article","created":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T20:54:48Z","timestamp":1634072088000},"page":"209-213","source":"Crossref","is-referenced-by-count":1,"title":["Hematemesis en un neonato con s\u00edndrome de Heiner. Reporte de caso"],"prefix":"10.29262","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1572-3992","authenticated-orcid":false,"given":"Ana\u00ed","family":"Ortega-Espinosa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4832-9126","authenticated-orcid":false,"given":"Miguel \u00c1ngel","family":"Mart\u00ednez-Benaiges","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9910-5421","authenticated-orcid":false,"given":"Norma Ang\u00e9lica","family":"Rojas-Pineda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2359-3614","authenticated-orcid":false,"given":"Blanca Mar\u00eda","family":"Morf\u00edn-Maciel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Sicherer SH, Sampson HA. 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M\u00e9xico: Corinter; 2017."}],"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/901\/1467","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/901\/1467","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,12]],"date-time":"2023-02-12T13:30:30Z","timestamp":1676208630000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,12]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,10,12]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v68i3.901","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"type":"electronic","value":"2448-9190"},{"type":"print","value":"0002-5151"}],"subject":[],"published":{"date-parts":[[2021,10,12]]}}}