{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T23:47:53Z","timestamp":1787615273961,"version":"build-2736575974"},"reference-count":19,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"2","license":[{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Objetivo: Determinar la prevalencia, causas y factores de riesgo en pacientes hospitalizados por eventos adversos a medicamentos.\nM\u00e9todos: Estudio de casos y controles, observacional y anal\u00edtico, llevado a cabo en pacientes hospitalizados por eventos adversos a medicamentos, atendidos en el Hospital General Dr. Eduardo V\u00e1zquez N, Puebla, M\u00e9xico, entre junio de 2019 y junio de 2021. Para el an\u00e1lisis estad\u00edstico se utilizaron porcentajes, frecuencias, promedios, raz\u00f3n de momios, c2 y regresi\u00f3n log\u00edstica binaria m\u00faltiple. Los datos se analizaron con el programa Statistical Package, for the Social Sciencies 23.\nResultados: Se registraron 132 pacientes (66 casos y 66 controles). Del grupo de casos se informaron 26 pacientes atendidos por error de medicaci\u00f3n y 40 con reacci\u00f3n adversa a medicamentos. La prevalencia de eventos adversos a medicamentos fue del 3.6%. Los medicamentos y factores asociados con eventos adversos m\u00e1s reportados fueron: antibi\u00f3ticos, antiinflamatorios; edad promedio de 35a\u00f1os (DE: 17.41); sexo: 39.3% hombres, 60.7% mujeres; servicios reportados con mayor atenci\u00f3n: Urgencias y Cirug\u00eda;\u00a0 s\u00edntomas principales: cut\u00e1neos; s\u00edntomas asociados con reacciones adversas a medicamentos: tipo A prurito [RM: 8.5, p = 0.001(IC95%: 0.035-0.393)], tipo B prurito [RM:11, p = 0.001 (IC95%: 0.021- 0.368)]; urticaria [RM: 19, p = 0.005(IC95%: 0.007-0.412)].\nConclusiones: La mayor parte de los eventos adversos a medicamentos se originan por errores de medicaci\u00f3n o reacciones adversas a f\u00e1rmacos tipo A; sin embargo, ambos pueden prevenirse. La seguridad del paciente debe ser prioridad al momento de prescribir cualquier tipo de medicamento.<\/jats:p>","DOI":"10.29262\/ram.v70i2.1117","type":"journal-article","created":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T07:15:17Z","timestamp":1688109317000},"page":"72-79","source":"Crossref","is-referenced-by-count":2,"title":["Eventos adversos a medicamentos en pacientes hospitalizados: prevalencia, causas y factores de riesgo"],"prefix":"10.29262","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5779-138X","authenticated-orcid":false,"given":"Maria del Rocio","family":"Hernandez Morales","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Manuel","family":"Ram\u00edrez S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleazar","family":"Mancilla Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma","family":"Lara D\u00e1valos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samara","family":"Nazarala S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita","family":"Aguirre Barbosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11808","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"key":"42591","doi-asserted-by":"crossref","unstructured":"-Leape L, Brennan T, Laird N. 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