{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T01:52:39Z","timestamp":1745373159491},"reference-count":1,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"3","license":[{"start":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T00:00:00Z","timestamp":1692576000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Antecedentes: Las enfermedades autoinflamatorias son un grupo heterog\u00e9neo de patolog\u00edas cuya prevalencia es indefinida hasta nuestra actualidad. Dentro de estas, el S\u00edndrome de Fiebre Peri\u00f3dica, Adenitis, Faringitis y Aftosis (PFAPA, por sus siglas en ingl\u00e9s) se determina como la m\u00e1s com\u00fan y de las mayormente estudiadas. Las alteraciones del neurodesarrollo y la conducta, entre estas las del Espectro Autista, son especialmente prevalentes en pacientes con enfermedades al\u00e9rgicas y autoinmunes, sin embargo, hay poco documentado en cuanto a su relaci\u00f3n con la autoinflamaci\u00f3n.\nReporte de caso: Se muestra el caso de un paciente con S\u00edndrome de Asperger con debut posterior de esta enfermedad autoinflamatoria.\nSe obtienen 2 biometr\u00edas hem\u00e1ticas semanales e inmunoglobulinas s\u00e9ricas completas, las cuales no muestran descenso en conteos de neutr\u00f3filos ni infraniveles ni supraniveles en las inmunoglobulinas.\nConclusi\u00f3n: Al reacudir a su cita de control refiere pico febril 2 d\u00edas previos, el cual ces\u00f3 con la administraci\u00f3n del esteroide, ya si presencia de \u00falceras orales en esta ocasi\u00f3n, cumpliendo los criterios modificados de Marshall. Por igual, se nota un gran cambio en su desenvolvimiento y cooperaci\u00f3n a la exploraci\u00f3n. Se determina la dualidad de este s\u00edndrome autoinflamatorio en un paciente con S\u00edndrome de Asperger.<\/jats:p>","DOI":"10.29262\/ram.v70i3.1260","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T08:03:22Z","timestamp":1694505802000},"page":"200","source":"Crossref","is-referenced-by-count":1,"title":["S\u00edndrome de fiebre peri\u00f3dica, adenitis, faringitis y aftosis en un preescolar con s\u00edndrome de Asperger: reporte de caso"],"prefix":"10.29262","volume":"70","author":[{"given":"Ra\u00fal Alberto","family":"Montero V\u00e1zquez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2023,8,21]]},"reference":[{"key":"54256","doi-asserted-by":"crossref","unstructured":"Chen MH, Su TP, Chen YS, et al. Comorbidity of Allergic and Autoimmune Diseases Among Patients With ADHD. J Atten Disord. 2017;21(3):219-227. doi:10.1177\/1087054712474686","DOI":"10.1177\/1087054712474686"}],"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1260\/2082","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1260\/2082","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T08:03:28Z","timestamp":1694505808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/1260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,21]]},"references-count":1,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,9,11]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v70i3.1260","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"value":"2448-9190","type":"electronic"},{"value":"0002-5151","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8,21]]}}}