{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T23:12:11Z","timestamp":1694646731567},"reference-count":1,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"3","license":[{"start":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T00:00:00Z","timestamp":1692576000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Objetivos: Confirmar la presencia de alergia a penicilina y amoxicilina mediante pruebas de exposici\u00f3n in vivo, en pacientes que refieren antecedente de reacci\u00f3n inmediata con estos medicamentos.\nM\u00e9todos: Estudio observacional, transversal, descriptivo y prolectivo. Se incluyeron pacientes entre 12 y 60 a\u00f1os con antecedente de reacci\u00f3n inmediata tras administraci\u00f3n de penicilina y\/o amoxicilina. Se realizaron pruebas cut\u00e1neas por prick e intrad\u00e9rmicas con bencilpeniciloil polilisina y penicilina G, as\u00ed como desaf\u00edo oral con amoxicilina.\nResultados: Se incluyeron 10 pacientes femeninos y 3 masculinos. La edad promedio fue 39 a\u00f1os. En 84,6% de los casos la \u00faltima reacci\u00f3n adversa a medicamentos ocurri\u00f3 10 a\u00f1os atr\u00e1s y en todos los casos se manifest\u00f3 con urticaria. S\u00f3lo en el 38,4% se corrobor\u00f3 alergia a penicilina. La reacci\u00f3n adversa m\u00e1s frecuente, tras las pruebas de exposici\u00f3n in vivo fue prurito en el 23%.\nConclusiones: Los pacientes con sospecha de alergia a penicilina se deben evaluar mediante pruebas de exposici\u00f3n in vivo con los determinantes mayores y menores, para corroborar o descartar reacciones al\u00e9rgicas y mejorar las condiciones de tratamiento.<\/jats:p>","DOI":"10.29262\/ram.v70i3.1261","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T08:03:14Z","timestamp":1694505794000},"page":"191","source":"Crossref","is-referenced-by-count":0,"title":["Diagn\u00f3stico de alergia inmediata para penicilina: estudio piloto"],"prefix":"10.29262","volume":"70","author":[{"given":"Julinela","family":"Armenta Morales","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dulce Mariel","family":"Ruiz Sanchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Rivero Yeverino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Sergio","family":"Papaqui Tapia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Jes\u00fas","family":"R\u00edos L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aida Ines","family":"L\u00f3pez Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chrystopherson  Gengyny","family":"Caballero Lopez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosahandi","family":"Pacheco Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2023,8,21]]},"reference":[{"key":"54257","doi-asserted-by":"crossref","unstructured":"Torres M, Franklin N, et al. Controversies in Drug Allergy: Beta-Lactam Hypersensitivity Testing. J ALLERGY CLIN IMMUNOL PRACT. 2019; 1 (7): 40-45.","DOI":"10.1016\/j.jaip.2018.07.051"}],"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1261\/2073","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1261\/2073","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T08:03:19Z","timestamp":1694505799000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/1261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,21]]},"references-count":1,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,9,11]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v70i3.1261","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"value":"2448-9190","type":"electronic"},{"value":"0002-5151","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8,21]]}}}