{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T04:22:24Z","timestamp":1748406144253,"version":"3.41.0"},"reference-count":10,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"1","license":[{"start":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T00:00:00Z","timestamp":1713830400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Antecedentes: El loxoscelismo es un cuadro cl\u00ednico t\u00f3xico provocado por la mordedura de ara\u00f1as del g\u00e9nero Loxosceles, con amplia distribuci\u00f3n en\u00a0todo el mundo.1 La fosfolipasa D es la responsable de la dermonecrosis, inflamaci\u00f3n, agregaci\u00f3n plaquetaria, hem\u00f3lisis, alteraci\u00f3n de la permeabilidad\u00a0vascular, citotoxicidad, nefrotoxicidad, insuficiencia renal aguda, entre otros s\u00edntomas implicados con esta prote\u00edna.\nReporte de caso: Paciente masculino de 27 a\u00f1os, que inici\u00f3 con un cuadro repentino de dolor intenso en la mano derecha, en el metacarpo y las articulaciones\u00a0metacarpofal\u00e1ngicas. Al examen cl\u00ednico, la extremidad superior se percibi\u00f3 con aumento de volumen, edema extenso, hiperemia y aumento\u00a0de la temperatura local; la lesi\u00f3n progres\u00f3 a necrosis extensa. Se realizaron fasciotom\u00edas, de distal a proximal, y liberaci\u00f3n del compartimento del\u00a0segundo y tercer dedo a trav\u00e9s de incisiones longitudinales radiales y cubitales. Se coloc\u00f3 un autoinjerto de piel, obtenido de la superficie anterior del\u00a0muslo derecho. Se administraron analg\u00e9sicos opioides, antiinflamatorios no esteroides, corticosteroides y antibi\u00f3ticos. La biopsia de piel reporto: infiltrado\u00a0inflamatorio con neutr\u00f3filos, ulceraci\u00f3n y colonias bacterianas. Luego de 27 d\u00edas tuvo evoluci\u00f3n favorable, por lo que se dio alta a su domicilio,\u00a0con seguimiento por personal del servicio de Consulta externa.\nConclusi\u00f3n: El loxoscelismo cut\u00e1neo, como causa de s\u00edndrome compartimental agudo de la mano, es poco com\u00fan, pero debe considerarse en un\u00a0\u00e1rea end\u00e9mica para Loxosceles spp. La descompresi\u00f3n quir\u00fargica de los compartimentos afectados representa un factor decisivo en el tratamiento\u00a0de los pacientes.<\/jats:p>","DOI":"10.29262\/ram.v71i1.1289","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T21:55:55Z","timestamp":1714168555000},"page":"47-51","source":"Crossref","is-referenced-by-count":0,"title":["Loxoscelismo con s\u00edndrome compartimental agudo: reporte de un caso con desenlace exitoso"],"prefix":"10.29262","volume":"71","author":[{"given":"Itzel Yoselin","family":"S\u00e1nchez-P\u00e9rez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yareni","family":"Ch\u00e1vez- R\u00edos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio Gerardo","family":"Moreno- Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Velasco-Medina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo Vel\u00e1zquez-S\u00e1mano","family":"Vel\u00e1zquez-Samano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4361-821X","authenticated-orcid":false,"given":"Espiridi\u00f3n","family":"Ramos-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2024,4,23]]},"reference":[{"key":"55473","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-020-02719-0"},{"key":"55474","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2019.11.002"},{"key":"55475","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/7640789"},{"key":"55476","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196908000-00022"},{"key":"55477","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.882"},{"key":"55478","doi-asserted-by":"publisher","DOI":"10.1177\/0009922810388510"},{"key":"55479","unstructured":"Schenone H. [Cutaneous loxoscelism with edematous predominance]. Boletin chileno de parasitologia. 1998;53(3-4):78-83. PubMed PMID: 10413884."},{"key":"55480","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0502-2021"},{"key":"55481","doi-asserted-by":"publisher","DOI":"10.1016\/j.wem.2020.12.005"},{"key":"55482","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2021.07.014"}],"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1289\/2145","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1289\/2146","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1289\/2145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T01:35:23Z","timestamp":1748396123000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/1289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,23]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,4,23]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v71i1.1289","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"type":"electronic","value":"2448-9190"},{"type":"print","value":"0002-5151"}],"subject":[],"published":{"date-parts":[[2024,4,23]]}}}