{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T05:16:26Z","timestamp":1733548586275,"version":"3.30.1"},"reference-count":11,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"2","license":[{"start":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T00:00:00Z","timestamp":1719705600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Background: Acute liver failure in pediatric age is a serious multisystem disease, characterized by a failure of the synthesis and detoxification function of the liver. Among the etiologies, viral infection should be investigated. Treatment is supportive and some cases require liver transplantation.\nCase report: A 2-year-old girl was admitted for acute liver failure. The PCR viral panel was positive for Adenovirus 41 and IgG antibodies to SARS-CoV-2 were also found. Supportive treatment was started without improvement, so intravenous immunoglobulin was administered, with resolution of the liver failure.\nConclusion: Immunoglobulin has immunomodulatory mechanisms in children with severe acute hepatitis of infectious etiology, so in some cases, its administration can be considered as adjuvant therapy.\nKeywords: Acute liver failure, Hepatitis, Adenovirus, Immunoglobulin.<\/jats:p>","DOI":"10.29262\/ram.v71i2.1275","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T18:18:58Z","timestamp":1733509138000},"page":"131-134","source":"Crossref","is-referenced-by-count":0,"title":["Insuficiencia hep\u00e1tica aguda por adenovirus tratada con inmunoglobulina intravenosa","Adenovirus-related acute liver failure treated with intravenous immunoglobulin"],"prefix":"10.29262","volume":"71","author":[{"family":"Melissa Zavala Rodr\u00edguez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Marco Antonio Mart\u00ednez Triana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Mar\u00eda del Roc\u00edo Hern\u00e1ndez Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rub\u00e9n","family":"Pe\u00f1a V\u00e9lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2024,6,30]]},"reference":[{"key":"57847","unstructured":"Ciocca M, Costaguta A, Cuarterolo M, Delagado L, et al. Insuficiencia hep\u00e1tica aguda pedi\u00e1trica. Grupo de trabajo de la Sociedad Latinoamericana de Gastroenterolog\u00eda, Hepatolog\u00eda y Nutrici\u00f3n Pedi\u00e1trica (SLAGHNP). Acta Gastroenterol Latinoam 2016; 46 (1): 52-70."},{"key":"57848","doi-asserted-by":"crossref","unstructured":"Squires JE, Alonso EM, Ibrahim SH, Kasper V, et al. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Diagnosis and Management of Pediatric Acute Liver Failure. J Pediatr Gastroenterol Nutr 2022; 74 (1): 138-58.","DOI":"10.1097\/MPG.0000000000003268"},{"key":"57849","doi-asserted-by":"crossref","unstructured":"Gutierrez-Sanchez HH, Shiau H, Baker JM, Saaybi S, et al. A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection. N Engl J Med 2022; 387 (7): 620-630. doi: 10.1056\/NEJMoa2206294","DOI":"10.1056\/NEJMoa2206294"},{"key":"57850","doi-asserted-by":"crossref","unstructured":"Pe\u00f1a-V\u00e9lez R, Mart\u00ednez-V\u00e1zquez AY, P\u00e9rez-Ric\u00e1rdez L. Acute hepatitis of unknown etiology: a proposed diagnostic approach. Bol Med Hosp Infant Mex 2022; 79 (4): 203-205.","DOI":"10.24875\/BMHIM.22000096"},{"key":"57851","doi-asserted-by":"crossref","unstructured":"Karpen SJ. Acute Hepatitis in Children in 2022 - Human Adenovirus 41? N Engl J Med 2022; 387 (7): 656-657.","DOI":"10.1056\/NEJMe2208409"},{"key":"57852","doi-asserted-by":"crossref","unstructured":"Gao SH, Gong MC, Song HM. Acute severe hepatitis of unknown origin in children: considerations from the perspective of immunology. World J Pediatr 2022; 18 (8): 529-532.","DOI":"10.1007\/s12519-022-00580-y"},{"key":"57853","doi-asserted-by":"crossref","unstructured":"Pe\u00f1a-V\u00e9lez R, L\u00f3pez-J\u00e1uregui O, Ch\u00e1vez-Aguilar LA, Calva R. Vigilancia epidemiol\u00f3gica de la hepatitis aguda de causa desconocida en tres hospitales de Puebla, M\u00e9xico. Salud Publica Mex 2023; 65 (3): 307-8.","DOI":"10.21149\/14596"},{"key":"57854","doi-asserted-by":"crossref","unstructured":"Brodin P, Arditi M. Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens. Lancet Gastroenterol Hepatol 2022; 7 (7): 594-595.","DOI":"10.1016\/S2468-1253(22)00166-2"},{"key":"57855","doi-asserted-by":"crossref","unstructured":"Perricone C, Triggianese P, Bursi R, Cafaro G, et al. Intravenous Immunoglobulins at the Crossroad of Autoimmunity and Viral Infections. Microorganisms 2021; 9 (1): 121.","DOI":"10.3390\/microorganisms9010121"},{"key":"57856","doi-asserted-by":"crossref","unstructured":"Moraga-Llop FA, Mar\u00eda O. Inmunoglobulinas en la profilaxis de las enfermedades infecciosas. An Pediatr\u00eda Contin 2011; 9 (3): 181-5.","DOI":"10.1016\/S1696-2818(11)70026-9"},{"key":"57857","doi-asserted-by":"crossref","unstructured":"Indolfi G, Czubkowski P, Fitzpatrick E, Gonzales E, et al. Acute Hepatitis of Unknown Etiology Among Young Children: Research Agenda by the ESPGHAN Hepatology Committee. J Pediatr Gastroenterol Nutr 2022; 75 (4): 543-548.","DOI":"10.1097\/MPG.0000000000003567"}],"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1275\/2230","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1275\/2222","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1275\/2230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T18:19:04Z","timestamp":1733509144000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/1275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,30]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,6,21]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v71i2.1275","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"value":"2448-9190","type":"electronic"},{"value":"0002-5151","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6,30]]}}}