{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:58:30Z","timestamp":1759334310423,"version":"build-2065373602"},"reference-count":3,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"3","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>\u00a0\nAntecedentes: El angioedema adquirido (AEA) es poco frecuente, suele aparecer despu\u00e9s de la cuarta d\u00e9cada de vida. Se caracteriza por episodios recurrentes de angioedema no puriginoso que afecta piel, tracto gastrointestinal y v\u00edas respiratorias superiores, siendo dificil distinguirlo del angioedema hereditario.\nReporte de caso: Cuadro cl\u00ednico: Hombre de 44 a\u00f1os que cuenta con antecedente de linfoma No Hodgkin (LNH) en 2021 remitido. Inicia en junio 2024 con angioedema facial de duraci\u00f3n de 5 horas, no doloroso no puriginoso. Niega reconocer factor ambiental, medicamentos o alimentos que lo exacerben, as\u00ed como antecedentes de atopia. Estudios de laboratorio\/imagen: BH, IgE, ANA,C3 y C4 normal. Perfil tiroideo sin alteraciones. VSG y Coproparasitoscopico normal. Prueba de suero autologo negativo. Pruebas de urticaria f\u00edsica negativas. C1 inhibidor pendiente. Se descarta posibles procesos infecciosos. Evoluci\u00f3n: Mejora parcialmente con antihistam\u00ednico. Enero 2025 presenta tos seca, que evoluciona a hemoptoicos. TAC tor\u00e1cica demuestra tumor en \u00e1pice derecho. La broncoscopia con toma de biopsia confirm\u00f3 infiltraci\u00f3n por LNH.\nConclusi\u00f3n: Existen dos formas de AEA, la tipo I con asosicaci\u00f3n reconocida con trastornos linfoproliferativos, representando el LNH un 20% de los casos. Puede preceder a la aparici\u00f3n del LNH con un promedio de 2.3 a\u00f1os, en este caso fue la primera manifestaci\u00f3n de reca\u00edda. Actualmente ha iniciado quimoterapia sin nuevos episodios de angioedema. El angioedema de aparici\u00f3n tard\u00eda en la etapa adulta puede asociarse a una variedad amplia de enfermedades subyacentes, siendo las neoplasias hematologicas un grupo significativo. La busqueda intencionada de datos cl\u00ednicos de neoplasias nos lleva a su identificaci\u00f3n oportuna.\nPalabras clave: Angioedema; Adquirido; Linfoma; No hodgkin; C1 inhibidor.<\/jats:p>","DOI":"10.29262\/ram.v72i3.1521","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T14:24:59Z","timestamp":1759242299000},"page":"234","source":"Crossref","is-referenced-by-count":0,"title":["&lt;b&gt;Angioedema adquirido asociado a linfoma no Hodgkin: presentaci\u00f3n de un caso cl\u00ednico &lt;\/b&gt;","&lt;b&gt;\u00a0 Acquired angioedema associated with non-Hodgkin lymphoma: a clinical case report\u00a0&lt;\/b&gt;"],"prefix":"10.29262","volume":"72","author":[{"given":"Diana Laura","family":"Alvarado Carrillo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itzel Yoselin","family":"S\u00e1nchez Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Aida","family":"Velasco Medina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Albarran Godinez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Vel\u00e1zquez Samano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"62737","doi-asserted-by":"crossref","unstructured":"1. Gunatilake, SSC, Wimalaratna, H. Angioedema como primera presentaci\u00f3n del linfoma no Hodgkin de c\u00e9lulas B: un caso inusual con niveles normales de inhibidor de la esterasa C1: reporte de un caso. BMC Res Notes 7 , 495 (2014). https:\/\/doi.org\/10.1186\/1756-0500-7-495","DOI":"10.1186\/1756-0500-7-495"},{"key":"62738","doi-asserted-by":"crossref","unstructured":"2. Breitbart SI, Bielory L. Acquired angioedema: Autoantibody associations and C1q utility as a diagnostic tool. Allergy Asthma Proc. 2010 Sep-Oct;31(5):428-34. doi: 10.2500\/aap.2010.31.3361. PMID: 20929611.","DOI":"10.2500\/aap.2010.31.3361"},{"key":"62739","unstructured":"3. Foti R, Fazio P, Lizzio G, Leonardi R. Angioedema: prima manifestazione di linfoma non Hodgkin [Angioedema: first manifestation of non-Hodgkin's lymphoma]. Ann Ital Med Int. 2002 Jul-Sep;17(3):185-8. Italian. PMID: 12402667."}],"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1521\/2770","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1521\/2770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T14:25:01Z","timestamp":1759242301000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/1521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":3,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,9,30]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v72i3.1521","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"type":"electronic","value":"2448-9190"},{"type":"print","value":"0002-5151"}],"subject":[],"published":{"date-parts":[[2025,9,30]]}}}