{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:58:32Z","timestamp":1759334312019,"version":"build-2065373602"},"reference-count":5,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"3","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Antecedentes: La sensibilizaci\u00f3n genuina a la carne de res y cerdo es rara, siendo el al\u00e9rgeno mejor caracterizado a la carne de res y cerdo (Bos d 6 y Sus s1). Existen diferentes presentaciones de alergia a carne de mam\u00edferos: s\u00edndrome gato-puerco, s\u00edndrome alfa-gal, alergia relacionada con alergenos de leche y sensibilizaci\u00f3n primaria.\nReporte de caso: Hombre 49 a\u00f1os, con urticaria posterior a la ingesta de carne de res y cerdo y s\u00edntomas nasales intermitentes leves. Se inicia abordaje con pruebas a aeroal\u00e9rgenos: positivo a gato, sospecha de s\u00edndrome de gato puerco se realiza prueba prick to prick a carne de cerdo crudo y cocida: positiva y carne de res crudo: positivo, carne de res cocida: indeterminado; se realizareto oral: positivo, presencia a los 40 minutos de lesiones tipo hab\u00f3n en cuello, t\u00f3rax anterior y cara. Se solicita Fel d 1 (.92 kual\/l) y Fel d 2 (0.05 kual\/l) confirmando sensibilizaci\u00f3n genuina a gato y descarta s\u00edndrome gato puerco. IgE especifica a cerdo (.18 kual\/l ), confirmando sensibilizaci\u00f3n a carne de puerco. Ante s\u00edntomas con carne de res y probabilidad de s\u00edndrome \u03b1-Gal, se realiza prueba cut\u00e1nea e intrad\u00e9rmica a poligelina: negativo. Bos d4 (.02kual\/l) y Bos d5 ( .01kual\/l) negativo, confirmado sensibilizaci\u00f3n primaria a carne de res.\nConclusi\u00f3n: Al descartar otros mecanismos, se presume una sensibilizaci\u00f3n primaria a carne de mam\u00edferos. El abordaje molecular puede mejorar la precisi\u00f3n diagn\u00f3stica y orientar la toma de decisiones terap\u00e9uticas en este caso:Evitaci\u00f3n total.\nPalabras clave: Reactividad cruzada; Hipersensibilidad tipo 1; S\u00edndrome gato-puerco; S\u00edndrome alfa-Gal; Hipersensibilidad a alimentos.<\/jats:p>","DOI":"10.29262\/ram.v72i3.1530","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T14:29:10Z","timestamp":1759242550000},"page":"240","source":"Crossref","is-referenced-by-count":0,"title":["&lt;b&gt;Sensibilizaci\u00f3n genuina a carne de mam\u00edfero tipo res y cerdo. \u00bfMito o realidad? &lt;\/b&gt;","&lt;b&gt;Genuine awareness of mammalian meat such as beef and pork: Myth or reality?\u00a0&lt;\/b&gt;"],"prefix":"10.29262","volume":"72","author":[{"given":"Alejandra","family":"Flores Montiel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Hern\u00e1ndez Ojeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia Mar\u00eda","family":"O\u00b4Farril Romanillos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Andrea","family":"Herrera S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Lizeth","family":"Garfias Zavala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Gil Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan David","family":"Rodr\u00edguez Moreno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"62984","doi-asserted-by":"crossref","unstructured":"Barradas Lopes J, Labrador-Horrilo M, Bartolom\u00e9 B, Cunha L. The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report. Acta Med Port. 2022;35(5):388-391. doi:10.20344\/amp.15483","DOI":"10.20344\/amp.15483"},{"key":"62985","doi-asserted-by":"crossref","unstructured":"Wilson JM, Platts-Mills TAE. Red meat allergy in children and adults. Curr Opin Allergy Clin Immunol. 2019;19(3):229-235. doi:10.1097\/ACI.0000000000000523","DOI":"10.1097\/ACI.0000000000000523"},{"key":"62986","doi-asserted-by":"crossref","unstructured":"Mamikoglu B. Beef, pork, and milk allergy (cross reactivity with each other and pet allergies). Otolaryngol Head Neck Surg. 2005;133(4):534-537. doi:10.1016\/j.otohns.2005.07.016","DOI":"10.1016\/j.otohns.2005.07.016"},{"key":"62987","doi-asserted-by":"crossref","unstructured":"Macdougall JD, Thomas KO, Iweala OI. The Meat of the Matter: Understanding and Managing Alpha-Gal Syndrome. Immunotargets Ther. 2022;11:37-54. Published 2022 Sep 15. doi:10.2147\/ITT.S276872","DOI":"10.2147\/ITT.S276872"},{"key":"62988","doi-asserted-by":"crossref","unstructured":"Wong XL, Sebaratnam DF. Mammalian meat allergy. Int J Dermatol. 2018;57(12):1433-1436. doi:10.1111\/ijd.14208","DOI":"10.1111\/ijd.14208"}],"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1530\/2775","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/1530\/2775","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T14:29:13Z","timestamp":1759242553000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/1530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,9,30]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v72i3.1530","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"type":"electronic","value":"2448-9190"},{"type":"print","value":"0002-5151"}],"subject":[],"published":{"date-parts":[[2025,9,30]]}}}