{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:39:15Z","timestamp":1753889955720,"version":"3.41.2"},"reference-count":24,"publisher":"Mastology","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mastology"],"abstract":"<jats:p>Introduction: The objective of this study was to correlate the features of invasive breast carcinoma in 18F-FDG positron emission tomography\/computed tomography with histopathological results, findings from other imaging methods, and survival. Methods: This observational single-center study included patients who underwent staging 18F-FDG positron emission tomography\/ computed tomography between September 2012 and April 2019; the results were correlated with the findings of other imaging tests and anatomopathological results. Lesions were evaluated for their maximum standardized uptake value on positron emission tomography\/computed tomography performed in the prone position. Tumors were classified into three subtypes (luminal, HER2 and triple-negative) based on immunohistochemical analyses. Results: A total of 125 patients with a mean age of 52 years (24\u201390 years) were analyzed. The primary tumor showed an increased 18F-FDG concentration on positron emission tomography\/computed tomography in 122 (97.6%) patients, with a mean maximum standardized uptake value of 7.15 (1.0\u201332.9 range). The mean maximum standardized uptake value was higher in the triple-negative subtype (11.4; n=24) than in the luminal (6.2; n=89) and HER2 (5.0; n=9) subtypes (p&lt;0.01). Tumors with more aggressive histological and immunohistochemical characteristics showed higher maximum standardized uptake values. Patients with a standardized uptake value greater than 7 in the primary tumor or greater than 6.7 in the axillary lymph nodes had poor overall survival (p=0.03 and p&lt;0.01, respectively). Conclusions: Our study suggests that the maximum standardized uptake value obtained on positron emission tomography\/computed tomography in the prone position may correlate with the tumor immunophenotype and overall survival regardless of the treatments performed, and can be used as a prognostic biomarker in invasive breast carcinoma patients.<\/jats:p>","DOI":"10.29289\/2594539420210062","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T10:05:49Z","timestamp":1649239549000},"source":"Crossref","is-referenced-by-count":0,"title":["Prognostic role of 18F-FDG PET-CT in the prone position in the evaluation of invasive breast carcinoma"],"prefix":"10.29289","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9260-2505","authenticated-orcid":false,"given":"Carla Chizuru","family":"Tajima","sequence":"first","affiliation":[{"name":"A Benefic\u00eancia Portuguesa de S\u00e3o Paulo, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1608-6964","authenticated-orcid":false,"given":"Eduardo N\u00f3brega Pereira","family":"Lima","sequence":"additional","affiliation":[{"name":"AC Camargo Cancer Center, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9640-4573","authenticated-orcid":false,"given":"Ramon Andrade Bezerra de","family":"Mello","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7572-9371","authenticated-orcid":false,"given":"Elvira Ferreira","family":"Marques","sequence":"additional","affiliation":[{"name":"AC Camargo Cancer Center, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0192-9885","authenticated-orcid":false,"given":"Almir Galv\u00e3o Vieira","family":"Bitencourt","sequence":"additional","affiliation":[{"name":"AC Camargo Cancer Center, Brazil"}]}],"member":"11842","published-online":{"date-parts":[[2021]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Brazil. 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