{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T06:07:29Z","timestamp":1780380449384,"version":"3.54.1"},"reference-count":40,"publisher":"Society of Nuclear Medicine","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nucl Med"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.2967\/jnumed.109.074344","type":"journal-article","created":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T16:25:07Z","timestamp":1283358307000},"page":"1395-1403","source":"Crossref","is-referenced-by-count":50,"title":["A New Pyrimidine-Specific Reporter Gene: A Mutated Human Deoxycytidine Kinase Suitable for PET During Treatment with Acycloguanosine-Based Cytotoxic Drugs"],"prefix":"10.2967","volume":"51","author":[{"given":"Yury","family":"Likar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Zurita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantin","family":"Dobrenkov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa","family":"Shenker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangde","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Neschadim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Medin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Sadelain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hedvig","family":"Hricak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Ponomarev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1602","published-online":{"date-parts":[[2010,9,1]]},"reference":[{"key":"2021051712005076000_51.9.1395.1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/978-3-540-77496-9_12","article-title":"Molecular imaging of PET reporter gene expression","volume":"185\/2","author":"Min","year":"2008","journal-title":"Handb Exp Pharmacol."},{"key":"2021051712005076000_51.9.1395.2","first-page":"287","article-title":"Monitoring gene therapy with herpes simplex virus thymidine kinase in hepatoma cells: uptake of specific substrates","volume":"38","author":"Haberkorn","year":"1997","journal-title":"J Nucl Med."},{"key":"2021051712005076000_51.9.1395.3","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cgt.7700795"},{"key":"2021051712005076000_51.9.1395.4","doi-asserted-by":"publisher","DOI":"10.1038\/nbt805"},{"key":"2021051712005076000_51.9.1395.5","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.107.047324"},{"key":"2021051712005076000_51.9.1395.6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0337418100"},{"key":"2021051712005076000_51.9.1395.7","doi-asserted-by":"publisher","DOI":"10.1038\/ncponc1278"},{"key":"2021051712005076000_51.9.1395.8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.161091198"},{"key":"2021051712005076000_51.9.1395.9","doi-asserted-by":"publisher","DOI":"10.1038\/sj.neo.7900204"},{"key":"2021051712005076000_51.9.1395.10","doi-asserted-by":"publisher","DOI":"10.1016\/S1095-0397(01)00071-1"},{"key":"2021051712005076000_51.9.1395.11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-08-3503"},{"key":"2021051712005076000_51.9.1395.12","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-04-015230"},{"key":"2021051712005076000_51.9.1395.13","doi-asserted-by":"publisher","DOI":"10.1038\/nm0296-216"},{"key":"2021051712005076000_51.9.1395.14","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-009-1089-x"},{"key":"2021051712005076000_51.9.1395.15","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1162\/15353500200504193","article-title":"hNIS-IRES-eGFP dual reporter gene imaging","volume":"4","author":"Che","year":"2005","journal-title":"Mol Imaging."},{"key":"2021051712005076000_51.9.1395.16","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.106.037812"},{"key":"2021051712005076000_51.9.1395.17","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(90)90217-Z"},{"key":"2021051712005076000_51.9.1395.18","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3300877"},{"key":"2021051712005076000_51.9.1395.19","doi-asserted-by":"publisher","DOI":"10.1038\/nm1208"},{"key":"2021051712005076000_51.9.1395.20","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1148\/radiol.2211001784","article-title":"Human transferrin receptor gene as a marker gene for MR imaging","volume":"221","author":"Moore","year":"2001","journal-title":"Radiology."},{"key":"2021051712005076000_51.9.1395.21","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.106.036962"},{"key":"2021051712005076000_51.9.1395.22","doi-asserted-by":"publisher","DOI":"10.1016\/0163-7258(95)00015-9"},{"key":"2021051712005076000_51.9.1395.23","doi-asserted-by":"publisher","DOI":"10.1038\/nm1724"},{"key":"2021051712005076000_51.9.1395.24","doi-asserted-by":"publisher","DOI":"10.1038\/nsb942"},{"key":"2021051712005076000_51.9.1395.25","doi-asserted-by":"publisher","DOI":"10.1021\/bi800157e"},{"key":"2021051712005076000_51.9.1395.26","doi-asserted-by":"publisher","DOI":"10.1021\/bi802062w"},{"key":"2021051712005076000_51.9.1395.27","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S1476-5586(03)80056-8","article-title":"Cytoplasmically retargeted HSV1-tk\/GFP reporter gene mutants for optimization of noninvasive molecular-genetic imaging","volume":"5","author":"Ponomarev","year":"2003","journal-title":"Neoplasia."},{"issue":"suppl 1","key":"2021051712005076000_51.9.1395.28","first-page":"S212","article-title":"Novel lentiviral cell fate control gene therapy based on engineered variants of the human deoxycytidine kinase [abstract]","volume":"16","author":"Neschadim","year":"2008","journal-title":"Mol Ther."},{"key":"2021051712005076000_51.9.1395.29","doi-asserted-by":"publisher","DOI":"10.1038\/sj.neo.7900018"},{"key":"2021051712005076000_51.9.1395.30","first-page":"59","article-title":"Methods for the construction of retroviral vectors and the generation of high titer producers","volume":"7","author":"Rivi\u00e8re","year":"1997","journal-title":"Meth Mol Biol."},{"key":"2021051712005076000_51.9.1395.31","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0436"},{"key":"2021051712005076000_51.9.1395.32","first-page":"6126","article-title":"Imaging the expression of transfected genes in vivo","volume":"55","author":"Tjuvajev","year":"1995","journal-title":"Cancer Res."},{"key":"2021051712005076000_51.9.1395.33","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-8051(97)00160-1"},{"key":"2021051712005076000_51.9.1395.34","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-0842"},{"key":"2021051712005076000_51.9.1395.35","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21014"},{"key":"2021051712005076000_51.9.1395.36","doi-asserted-by":"publisher","DOI":"10.1038\/nm1676"},{"key":"2021051712005076000_51.9.1395.37","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.5.2.295"},{"key":"2021051712005076000_51.9.1395.38","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.1.2.283"},{"key":"2021051712005076000_51.9.1395.39","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2008.01.048"},{"key":"2021051712005076000_51.9.1395.40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.22.11941"}],"container-title":["Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.2967\/jnumed.109.074344","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T19:25:42Z","timestamp":1621279542000},"score":1,"resource":{"primary":{"URL":"http:\/\/jnm.snmjournals.org\/lookup\/doi\/10.2967\/jnumed.109.074344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":40,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2010,9,1]]},"published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.2967\/jnumed.109.074344"],"URL":"https:\/\/doi.org\/10.2967\/jnumed.109.074344","relation":{},"ISSN":["0161-5505","2159-662X"],"issn-type":[{"value":"0161-5505","type":"print"},{"value":"2159-662X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}