{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T00:16:01Z","timestamp":1793924161921,"version":"4.8.0"},"reference-count":24,"publisher":"Society of Nuclear Medicine","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nucl Med"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.2967\/jnumed.122.263948","type":"journal-article","created":{"date-parts":[[2022,8,11]],"date-time":"2022-08-11T22:00:15Z","timestamp":1660255215000},"page":"287-293","source":"Crossref","is-referenced-by-count":23,"title":["Investigating Tau and Amyloid Tracer Skull Binding in Studies of Alzheimer Disease"],"prefix":"10.2967","volume":"64","author":[{"given":"Shaney","family":"Flores","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles D.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aylin","family":"Dincer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah J.","family":"Keefe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole S.","family":"McKay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela M.","family":"Paulick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria Guzman","family":"Perez-Carrillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russ C.","family":"Hornbeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manu","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Vlassenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Nickels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean F.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhude","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan E.","family":"McConathy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tammie L.S.","family":"Benzinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian A.","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1602","published-online":{"date-parts":[[2022,8,11]]},"reference":[{"key":"2023031310500857000_64.2.287.1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaf2362"},{"key":"2023031310500857000_64.2.287.2","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.117.195248"},{"key":"2023031310500857000_64.2.287.3","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s40478-016-0315-6","article-title":"An autoradiographic evaluation of AV-1451 tau PET in dementia","volume":"4","author":"Lowe","year":"2016","journal-title":"Acta Neuropathol Commun."},{"key":"2023031310500857000_64.2.287.4","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.117.198960"},{"key":"2023031310500857000_64.2.287.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-019-04496-0"},{"key":"2023031310500857000_64.2.287.6","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3233\/JAD-122059","article-title":"Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807","volume":"34","author":"Chien","year":"2013","journal-title":"J Alzheimers Dis."},{"key":"2023031310500857000_64.2.287.7","doi-asserted-by":"crossref","first-page":"102708","DOI":"10.1016\/j.nicl.2021.102708","article-title":"Sex differences in off-target binding using tau positron emission tomography","volume":"31","author":"Smith","year":"2021","journal-title":"Neuroimage Clin."},{"key":"2023031310500857000_64.2.287.8","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.115.164822"},{"key":"2023031310500857000_64.2.287.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.01.057"},{"key":"2023031310500857000_64.2.287.10","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.107.048330"},{"key":"2023031310500857000_64.2.287.11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073377"},{"key":"2023031310500857000_64.2.287.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2018.12.008"},{"key":"2023031310500857000_64.2.287.13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.neuroimage.2017.07.050","article-title":"AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: defining a summary measure","volume":"161","author":"Mishra","year":"2017","journal-title":"Neuroimage."},{"key":"2023031310500857000_64.2.287.14","doi-asserted-by":"crossref","first-page":"289\u2013317","DOI":"10.32614\/RJ-2016-021","article-title":"Mclust 5: clustering, classification and density estimation using Gaussian finite mixture models","volume":"8","author":"Scrucca","year":"2016","journal-title":"R J."},{"key":"2023031310500857000_64.2.287.15","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(99)01466-3"},{"key":"2023031310500857000_64.2.287.16","unstructured":"Amyvid EU Summary of Product Characteristics. European Medicines Agency; 2013."},{"key":"2023031310500857000_64.2.287.17","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00414-010-0544-3","article-title":"Age and gender-dependent bone density changes of the human skull disclosed by high-resolution flat-panel computed tomography","volume":"125","author":"Schulte-Geers","year":"2011","journal-title":"Int J Legal Med."},{"key":"2023031310500857000_64.2.287.18","doi-asserted-by":"crossref","unstructured":"Kolabas ZI Kuemmerle LB Perneczky R .Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation. bioRxiv website. https:\/\/www.biorxiv.org\/content\/10.1101\/2021.12.24.473988v1. Published December 25, 2021. Accessed November 18, 2022.","DOI":"10.1101\/2021.12.24.473988"},{"key":"2023031310500857000_64.2.287.19","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1093\/brain\/awaa089","article-title":"Relationship between cortical iron and tau aggregation in Alzheimer\u2019s disease","volume":"143","author":"Spotorno","year":"2020","journal-title":"Brain."},{"key":"2023031310500857000_64.2.287.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.07.050"},{"key":"2023031310500857000_64.2.287.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2018.08.022"},{"key":"2023031310500857000_64.2.287.22","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1002\/ana.25878","article-title":"Sex mediates relationships between regional tau pathology and cognitive decline","volume":"88","author":"Buckley","year":"2020","journal-title":"Ann Neurol."},{"key":"2023031310500857000_64.2.287.23","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/WAD.0000000000000393","article-title":"Sex-related differences in tau positron emission tomography (PET) and the effects of hormone therapy (HT)","volume":"35","author":"Wisch","year":"2021","journal-title":"Alzheimer Dis Assoc Disord."},{"key":"2023031310500857000_64.2.287.24","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/ana.26382","article-title":"Menopause status moderates sex differences in tau burden: a Framingham PET study","volume":"92","author":"Buckley","year":"2022","journal-title":"Ann Neurol."}],"container-title":["Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.2967\/jnumed.122.263948","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T17:51:47Z","timestamp":1678729907000},"score":1,"resource":{"primary":{"URL":"http:\/\/jnm.snmjournals.org\/lookup\/doi\/10.2967\/jnumed.122.263948"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,11]]},"references-count":24,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2,1]]},"published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.2967\/jnumed.122.263948"],"URL":"https:\/\/doi.org\/10.2967\/jnumed.122.263948","relation":{},"ISSN":["0161-5505","2159-662X"],"issn-type":[{"value":"0161-5505","type":"print"},{"value":"2159-662X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,11]]}}}