{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:59:14Z","timestamp":1788544754391,"version":"build-2803163510"},"reference-count":33,"publisher":"Society of Nuclear Medicine","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nucl Med"],"accepted":{"date-parts":[[2024,12,2]]},"published-print":{"date-parts":[[2025,2]]},"DOI":"10.2967\/jnumed.124.268365","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T17:35:23Z","timestamp":1735839323000},"page":"286-292","source":"Crossref","is-referenced-by-count":7,"title":["Longitudinal Trajectory of Dopamine and Serotonin Transporters in Parkinson Disease"],"prefix":"10.2967","volume":"66","author":[{"given":"Yujin","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Hyeok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Kyeol","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Hoon","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han Soo","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chul Hyoung","family":"Lyoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1602","published-online":{"date-parts":[[2025,1,2]]},"reference":[{"key":"2025020306150624000_66.2.286.1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awt192"},{"key":"2025020306150624000_66.2.286.2","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2020.00026"},{"key":"2025020306150624000_66.2.286.3","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03802-y"},{"key":"2025020306150624000_66.2.286.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.03.012"},{"key":"2025020306150624000_66.2.286.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02900.x"},{"key":"2025020306150624000_66.2.286.6","doi-asserted-by":"crossref","first-page":"e76595","DOI":"10.1371\/journal.pone.0076595","article-title":"The nature of progression in Parkinson\u2019s disease: an application of non-linear, multivariate, longitudinal random effects modelling","volume":"8","author":"Kuramoto","year":"2013","journal-title":"PLoS One."},{"key":"2025020306150624000_66.2.286.7","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.64.3.314"},{"key":"2025020306150624000_66.2.286.8","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.3.378"},{"key":"2025020306150624000_66.2.286.9","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.parkreldis.2022.08.006","article-title":"Temporal trajectory model for dopaminergic input to the striatal subregions in Parkinson\u2019s disease","volume":"103","author":"Kim","year":"2022","journal-title":"Parkinsonism Relat Disord."},{"key":"2025020306150624000_66.2.286.10","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/114.5.2283"},{"key":"2025020306150624000_66.2.286.11","doi-asserted-by":"crossref","first-page":"103347","DOI":"10.1016\/j.nicl.2023.103347","article-title":"Longitudinal DAT changes measured with [18F]FE-PE2I PET in patients with Parkinson\u2019s disease: a validation study","volume":"37","author":"Kerstens","year":"2023","journal-title":"Neuroimage Clin."},{"key":"2025020306150624000_66.2.286.12","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600599"},{"key":"2025020306150624000_66.2.286.13","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2010.05.028"},{"key":"2025020306150624000_66.2.286.14","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5666-5"},{"key":"2025020306150624000_66.2.286.15","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv215"},{"key":"2025020306150624000_66.2.286.16","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.115.153734"},{"key":"2025020306150624000_66.2.286.17","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.parkreldis.2019.03.025","article-title":"Progressive loss of raphe nuclei serotonin transporter in early Parkinson\u2019s disease: a longitudinal 123I-FP-CIT SPECT study","volume":"77","author":"Pasquini","year":"2020","journal-title":"Parkinsonism Relat Disord."},{"key":"2025020306150624000_66.2.286.18","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26424"},{"key":"2025020306150624000_66.2.286.19","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25122"},{"key":"2025020306150624000_66.2.286.20","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.149.2.351"},{"key":"2025020306150624000_66.2.286.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.04.065"},{"key":"2025020306150624000_66.2.286.22","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.1.2"},{"key":"2025020306150624000_66.2.286.23","doi-asserted-by":"crossref","first-page":"948523","DOI":"10.3389\/fnins.2022.948523","article-title":"Post-mortem brain histological examination in the substantia nigra and subthalamic nucleus in Parkinson\u2019s disease following deep brain stimulation","volume":"16","author":"Mazumder","year":"2022","journal-title":"Front Neurosci."},{"key":"2025020306150624000_66.2.286.24","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30319-9"},{"key":"2025020306150624000_66.2.286.25","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awz296"},{"key":"2025020306150624000_66.2.286.26","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.8.1437"},{"key":"2025020306150624000_66.2.286.27","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1002\/mds.29220","article-title":"Serotonin transporter imaging in multiple system atrophy and Parkinson\u2019s disease","volume":"37","author":"Chou","year":"2022","journal-title":"Mov Disord."},{"key":"2025020306150624000_66.2.286.28","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30140-1"},{"key":"2025020306150624000_66.2.286.29","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1007\/s00259-020-04683-4","article-title":"High-resolution PET imaging reveals subtle impairment of the serotonin transporter in an early non-depressed Parkinson\u2019s disease cohort","volume":"47","author":"Fazio","year":"2020","journal-title":"Eur J Nucl Med Mol Imaging."},{"key":"2025020306150624000_66.2.286.30","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s13139-024-00840-x","article-title":"Imaging procedure and clinical studies of [18F] FP-CIT PET","volume":"58","author":"Sung","year":"2024","journal-title":"Nucl Med Mol Imaging."},{"key":"2025020306150624000_66.2.286.31","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s13139-014-0286-0","article-title":"The effect of SSRIs on the binding of 18F-FP-CIT in Parkinson patients: a retrospective case control study","volume":"48","author":"Seo","year":"2014","journal-title":"Nucl Med Mol Imaging."},{"key":"2025020306150624000_66.2.286.32","doi-asserted-by":"publisher","DOI":"10.1172\/JCI71640"},{"key":"2025020306150624000_66.2.286.33","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2007.03.016"}],"container-title":["Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.2967\/jnumed.124.268365","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T14:17:13Z","timestamp":1738592233000},"score":1,"resource":{"primary":{"URL":"http:\/\/jnm.snmjournals.org\/lookup\/doi\/10.2967\/jnumed.124.268365"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,2]]},"references-count":33,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2,3]]},"published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.2967\/jnumed.124.268365"],"URL":"https:\/\/doi.org\/10.2967\/jnumed.124.268365","relation":{},"ISSN":["0161-5505","2159-662X"],"issn-type":[{"value":"0161-5505","type":"print"},{"value":"2159-662X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,2]]}}}