{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:06:18Z","timestamp":1792760778814,"version":"4.5.0"},"reference-count":39,"publisher":"Society of Nuclear Medicine","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nucl Med"],"accepted":{"date-parts":[[2025,11,13]]},"published-print":{"date-parts":[[2026,3]]},"DOI":"10.2967\/jnumed.125.270958","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T16:50:24Z","timestamp":1765471824000},"page":"397-403","source":"Crossref","is-referenced-by-count":6,"title":["CD70-Targeted [\n                    <sup>18<\/sup>\n                    F]RCCB6 Immuno-PET\/CT for Diagnosing Clear Cell Renal Cell Carcinoma Metastases: A Prospective Study"],"prefix":"10.2967","volume":"67","author":[{"given":"Cheng","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianghua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianyun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongsheng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuxian","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihui","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijun","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1602","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"2026030205300690000_67.3.397.1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdz056"},{"key":"2026030205300690000_67.3.397.2","doi-asserted-by":"crossref","first-page":"17009","DOI":"10.1038\/nrdp.2017.9","article-title":"Renal cell carcinoma","volume":"3","author":"Hsieh","year":"2017","journal-title":"Nat Rev Dis Primers."},{"key":"2026030205300690000_67.3.397.3","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1080\/14728214.2016.1244263","article-title":"Emerging growth factor receptor antagonists for the treatment of renal cell carcinoma","volume":"21","author":"Zahoor","year":"2016","journal-title":"Expert Opin Emerg Drugs."},{"key":"2026030205300690000_67.3.397.4","doi-asserted-by":"crossref","first-page":"e2021869","DOI":"10.1001\/jamanetworkopen.2020.21869","article-title":"Evaluation of clear cell, papillary, and chromophobe renal cell carcinoma metastasis sites and association with survival","volume":"4","author":"Dudani","year":"2021","journal-title":"JAMA. Netw Open."},{"key":"2026030205300690000_67.3.397.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2017.06.060"},{"key":"2026030205300690000_67.3.397.6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1601333"},{"key":"2026030205300690000_67.3.397.7","first-page":"645","article-title":"Surgical intervention for pulmonary metastases","volume":"109","author":"Pfannschmidt","year":"2012","journal-title":"Dtsch Arztebl Int."},{"key":"2026030205300690000_67.3.397.8","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.8381"},{"key":"2026030205300690000_67.3.397.9","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/s41585-024-00962-z","article-title":"Molecular imaging of renal cell carcinomas: ready for prime time","volume":"22","author":"Wu","year":"2025","journal-title":"Nat Rev Urol."},{"key":"2026030205300690000_67.3.397.10","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.eururo.2022.01.040","article-title":"Novel imaging methods for renal mass characterization: a collaborative review","volume":"81","author":"Roussel","year":"2022","journal-title":"Eur Urol."},{"key":"2026030205300690000_67.3.397.11","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1038\/s41585-024-00876-w","article-title":"Von Hippel-Lindau protein signalling in clear cell renal cell carcinoma","volume":"21","author":"Liao","year":"2024","journal-title":"Nat Rev Urol."},{"key":"2026030205300690000_67.3.397.12","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i2.155"},{"key":"2026030205300690000_67.3.397.13","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.semcancer.2022.01.001","article-title":"Carbonic anhydrase IX: a tumor acidification switch in heterogeneity and chemokine regulation","volume":"86","author":"Queen","year":"2022","journal-title":"Semin Cancer Biol."},{"key":"2026030205300690000_67.3.397.14","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-021-02215-y"},{"key":"2026030205300690000_67.3.397.15","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.124.268509"},{"key":"2026030205300690000_67.3.397.16","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.clgc.2023.12.003","article-title":"CD70 is consistently expressed in primary and metastatic clear cell renal cell carcinoma","volume":"22","author":"Huang","year":"2024","journal-title":"Clin Genitourin Cancer."},{"key":"2026030205300690000_67.3.397.17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00738"},{"key":"2026030205300690000_67.3.397.18","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.122.263907"},{"key":"2026030205300690000_67.3.397.19","doi-asserted-by":"crossref","unstructured":"Shi B Zhou X Zhou J . CD70-targeted radiotheranostics: now and future. Semin Nucl Med. September 18, 2025 [Epub ahead of print].","DOI":"10.1053\/j.semnuclmed.2025.08.001"},{"key":"2026030205300690000_67.3.397.20","doi-asserted-by":"crossref","first-page":"100671","DOI":"10.1016\/j.medj.2025.100671","article-title":"CD70-targeted cancer theranostics: progress and challenges","volume":"6","author":"Wei","year":"2025","journal-title":"Med."},{"key":"2026030205300690000_67.3.397.21","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1007\/s00259-024-06672-3","article-title":"ImmunoPET\/CT imaging of clear cell renal cell carcinoma with [18F]RCCB6: a first-in-human study","volume":"51","author":"Wu","year":"2024","journal-title":"Eur J Nucl Med Mol Imaging."},{"key":"2026030205300690000_67.3.397.22","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.eururo.2024.06.020","article-title":"[18F]RCCB6 immuno-positron emission tomography\/computed tomography for postoperative surveillance in clear cell renal cell carcinoma: a pilot clinical study","volume":"86","author":"Wu","year":"2024","journal-title":"Eur Urol."},{"key":"2026030205300690000_67.3.397.23","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1007\/s00259-024-07001-4","article-title":"[18F]RCCB6 immunoPET\/CT detects primary clear cell renal cell carcinoma","volume":"52","author":"Wu","year":"2025","journal-title":"Eur J Nucl Med Mol Imaging."},{"key":"2026030205300690000_67.3.397.24","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.119.230565"},{"key":"2026030205300690000_67.3.397.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.modpat.2023.100398"},{"key":"2026030205300690000_67.3.397.26","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1182\/blood.2024025536","article-title":"Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR T cells","volume":"146","author":"Kasap","year":"2025","journal-title":"Blood."},{"key":"2026030205300690000_67.3.397.27","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(24)00508-4"},{"key":"2026030205300690000_67.3.397.28","doi-asserted-by":"crossref","first-page":"101889","DOI":"10.1016\/j.xcrm.2024.101889","article-title":"CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive T cells","volume":"6","author":"Wang","year":"2025","journal-title":"Cell Rep Med."},{"key":"2026030205300690000_67.3.397.29","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.Cd-24-0102"},{"key":"2026030205300690000_67.3.397.30","doi-asserted-by":"crossref","first-page":"102321","DOI":"10.1016\/j.xcrm.2025.102321","article-title":"Multimodal targeting of metastatic renal cell carcinoma via CD70-directed allogeneic CAR-NKT cells","volume":"6","author":"Li","year":"2025","journal-title":"Cell Rep Med."},{"key":"2026030205300690000_67.3.397.31","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1002\/cncr.31912","article-title":"A phase 1 trial of SGN-CD70A in patients with CD70-positive, metastatic renal cell carcinoma","volume":"125","author":"Pal","year":"2019","journal-title":"Cancer."},{"key":"2026030205300690000_67.3.397.32","doi-asserted-by":"crossref","first-page":"e70400","DOI":"10.1002\/ctm2.70400","article-title":"CD70: an emerging target for integrated cancer diagnosis and therapy","volume":"15","author":"Hu","year":"2025","journal-title":"Clin Transl Med."},{"key":"2026030205300690000_67.3.397.33","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/s00259-023-06454-3","article-title":"ImmunoPET imaging of Trop2 expression in solid tumors with nanobody tracers","volume":"51","author":"Huang","year":"2024","journal-title":"Eur J Nucl Med Mol Imaging."},{"key":"2026030205300690000_67.3.397.34","doi-asserted-by":"crossref","unstructured":"Zhang Y Cao M Wu Y . Preclinical development of novel PD-L1 tracers and first-in-human study of [68Ga]Ga-NOTA-RW102 in patients with lung cancers. J Immunother Cancer. 2024;12:e008794.","DOI":"10.1136\/jitc-2024-008794"},{"key":"2026030205300690000_67.3.397.35","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr362"},{"key":"2026030205300690000_67.3.397.36","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.eururo.2024.10.013","article-title":"Re: [89Zr]Zr-girentuximab for PET-CT imaging of clear-cell renal cell carcinoma: a prospective, open-label, multicentre, phase 3 trial","volume":"87","author":"Campi","year":"2025","journal-title":"Eur Urol."},{"key":"2026030205300690000_67.3.397.37","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.eururo.2024.03.028","article-title":"Re: First-in-human safety, imaging, and dosimetry of a carbonic anhydrase IX-targeting peptide, [68Ga]Ga-DPI-4452, in patients with clear cell renal cell carcinoma","volume":"86","author":"Thomson","year":"2024","journal-title":"Eur Urol."},{"key":"2026030205300690000_67.3.397.38","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.123.266309"},{"key":"2026030205300690000_67.3.397.39","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1007\/s00259-024-06801-y","article-title":"Diagnostic efficacy of [68Ga]Ga-NY104 PET\/CT to identify clear cell renal cell carcinoma","volume":"51","author":"Zhu","year":"2024","journal-title":"Eur J Nucl Med Mol Imaging."}],"container-title":["Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.2967\/jnumed.125.270958","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T13:30:58Z","timestamp":1772458258000},"score":1,"resource":{"primary":{"URL":"http:\/\/jnm.snmjournals.org\/lookup\/doi\/10.2967\/jnumed.125.270958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,11]]},"references-count":39,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,3,2]]},"published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.2967\/jnumed.125.270958"],"URL":"https:\/\/doi.org\/10.2967\/jnumed.125.270958","relation":{},"ISSN":["0161-5505","2159-662X"],"issn-type":[{"value":"0161-5505","type":"print"},{"value":"2159-662X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,11]]}}}