{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:30:49Z","timestamp":1783632649307,"version":"3.55.0"},"reference-count":19,"publisher":"American Mosquito Control Association","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12]]},"abstract":"ABSTRACT<\/jats:title>\n The present research aimed to evaluate the larvicidal activity of several recently discovered natural repellents formulated in lotions against larvae of Aedes aegypti<\/jats:italic>. We used a modified larval bioassay method by the World Health Organization standards in evaluating larval mortality at 24-, 48-, and 72-h exposure. Among the test repellents, 2-undecanone showed 100% mortality of Ae. aegypti<\/jats:italic> larvae, followed by catnip oil, capric acid, coconut oil fatty acids, methyl caprate, methyl laurate, and coconut oil methyl esters. The repellent, 2-undecanone showed median lethal concentration (LC50<\/jats:sub>) values of 73.07, 26.45, and 15.68 ppm at 24-, 48-, and 72-h exposure, respectively. Larvicidal activity varied among the other repellents tested.<\/jats:p>","DOI":"10.2987\/20-6916.1","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T10:14:24Z","timestamp":1613729664000},"page":"227-232","source":"Crossref","is-referenced-by-count":2,"title":["Larvicididal Activity of Natural Repellents Against the Dengue Vector, Aedes aegypti"],"prefix":"10.2987","volume":"36","author":[{"given":"Shougang","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Blore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui-De","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Whitney A.","family":"Qualls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Cermak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Wei","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1569","reference":[{"key":"i8756-971X-36-4-227-AlAbri1","series-title":"Int J Infect Dis","first-page":"97","article-title":"Control of the 2018\u20132019 dengue fever outbreak in Oman: a country previously without local transmission","volume":"90","author":"Al-Abri","year":"2019","unstructured":"Al-Abri\n SS,\n \n \n Kurup\n PJ,\n \n \n Al Manji\n A,\n \n \n Al Kindi\n H,\n \n \n Al Wahaibi\n A,\n \n \n Al Jardani\n A,\n \n \n Mahmoud\n OA,\n \n \n Al Balushi\n L,\n \n \n Al Rawahi\n B,\n \n \n Al Fahdi\n F,\n \n \n Al Siyabi\n H,\n \n \n Al Balushi\n Z,\n \n \n Al Mahrooqi\n S,\n \n \n Al Manji\n A,\n \n \n Al Sharji\n A,\n \n \n Al Harthi\n K,\n \n \n Al Abri\n B,\n \n \n Al-Raidan\n A,\n \n \n Al Bahri\n Z,\n \n \n Al-Mukhaini\n S,\n \n \n Amin\n M,\n \n \n Prasanna\n AR,\n \n \n Petersen\n E,\n \n \n Al Ajmi\n F.\n \n \n 2019.\n\t\t\t\t\tControl of the 2018\u20132019 dengue fever outbreak in Oman: a country previously without local transmission.\n\t\t\t\t\tInt J Infect Dis90:\n\t\t\t\t\t97\u2013\n\t\t\t\t\t103."},{"key":"i8756-971X-36-4-227-AmeliaYap1","series-title":"Parasit Vectors","first-page":"332","article-title":"Pyrethroid resistance in the dengue vector Aedes aegypti in Southeast Asia: present situation and prospects for management","volume":"11","author":"Amelia-Yap","year":"2018","unstructured":"Amelia-Yap\n ZH,\n \n \n Chen\n CD,\n \n \n Sofian-Azirun\n M,\n \n \n Low\n VL.\n \n \n 2018.\n\t\t\t\t\tPyrethroid resistance in the dengue vector Aedes aegypti in Southeast Asia: present situation and prospects for management.\n\t\t\t\t\tParasit Vectors11:\n\t\t\t\t\t332\u2013\n\t\t\t\t\t348."},{"key":"i8756-971X-36-4-227-Bernier1","series-title":"J Med Entomol","first-page":"306","article-title":"Comparison of contact and spatial repellency of catnip oil and N, N-diethyl-3-methylbenzamide (deet) against mosquitoes","volume":"42","author":"Bernier","year":"2005","unstructured":"Bernier\n UR,\n \n \n Furman\n KD,\n \n \n Kline\n DL,\n \n \n Allan\n SA,\n \n \n Barnard\n DR.\n \n \n 2005.\n\t\t\t\t\tComparison of contact and spatial repellency of catnip oil and N, N-diethyl-3-methylbenzamide (deet) against mosquitoes.\n\t\t\t\t\tJ Med Entomol42:\n\t\t\t\t\t306\u2013\n\t\t\t\t\t311."},{"key":"i8756-971X-36-4-227-Dusfour1","series-title":"PLoS Negl Trop Dis","first-page":"e0007615","article-title":"Management of insecticide resistance in the major Aedes vectors of arboviruses: advances and challenges","volume":"13","author":"Dusfour","year":"2019","unstructured":"Dusfour\n I,\n \n \n Vontas\n J,\n \n \n David\n JP,\n \n \n Weetman\n D,\n \n \n Fonseca\n DM,\n \n \n Corbel\n V,\n \n \n Raghavendra\n K,\n \n \n Coulibaly\n MB,\n \n \n Martins\n AJ,\n \n \n Kasai\n S,\n \n \n Chandre\n F.\n \n \n 2019.\n\t\t\t\t\tManagement of insecticide resistance in the major Aedes vectors of arboviruses: advances and challenges.\n\t\t\t\t\tPLoS Negl Trop Dis13:\n\t\t\t\t\te0007615."},{"key":"i8756-971X-36-4-227-Foley1","series-title":"J Am Mosq Control Assoc","first-page":"477","article-title":"Laboratory evaluation of methylated coconut oil as a larvicide for Anopheles farauti and Culex annulirostris","volume":"21","author":"Foley","year":"2005","unstructured":"Foley\n DH,\n \n \n Frances\n SP.\n \n \n 2005.\n\t\t\t\t\tLaboratory evaluation of methylated coconut oil as a larvicide for Anopheles farauti and Culex annulirostris.\n\t\t\t\t\tJ Am Mosq Control Assoc21:\n\t\t\t\t\t477\u2013\n\t\t\t\t\t479."},{"key":"i8756-971X-36-4-227-Ghosh1","series-title":"Indian J Med Res","first-page":"581","article-title":"Plant extracts as potential mosquito larvicides","volume":"135","author":"Ghosh","year":"2012","unstructured":"Ghosh\n A,\n \n \n Chowdhury\n N,\n \n \n Chandra\n G.\n \n \n 2012.\n\t\t\t\t\tPlant extracts as potential mosquito larvicides.\n\t\t\t\t\tIndian J Med Res135:\n\t\t\t\t\t581\u2013\n\t\t\t\t\t598."},{"key":"i8756-971X-36-4-227-Grant1","series-title":"PLoS One","first-page":"e21785","article-title":"Functional characterization of the octenol receptor neuron on the maxillary palps of the yellow fever mosquito, Aedes aegypti","volume":"6","author":"Grant","year":"2011","unstructured":"Grant\n AJ,\n \n \n Dickens\n JC.\n \n \n 2011.\n\t\t\t\t\tFunctional characterization of the octenol receptor neuron on the maxillary palps of the yellow fever mosquito, Aedes aegypti.\n\t\t\t\t\tPLoS One6:\n\t\t\t\t\te21785."},{"key":"i8756-971X-36-4-227-Liu1","series-title":"Parasit Vectors","first-page":"561","article-title":"The expanding pattern of Aedes aegypti in southern Yunnan, China: insights from microsatellite and mitochondrial DNA markers","volume":"12","author":"Liu","year":"2019","unstructured":"Liu\n P,\n \n \n Lu\n L,\n \n \n Jiang\n J,\n \n \n Guo\n Y,\n \n \n Yang\n M,\n \n \n Liu\n Q.\n \n \n 2019.\n\t\t\t\t\tThe expanding pattern of Aedes aegypti in southern Yunnan, China: insights from microsatellite and mitochondrial DNA markers.\n\t\t\t\t\tParasit Vectors12:\n\t\t\t\t\t561\u2013\n\t\t\t\t\t572."},{"key":"i8756-971X-36-4-227-Martin1","series-title":"Appl Environ Microbiol","first-page":"e01202","article-title":"Mosquito-borne viruses and insect-specific viruses revealed in field-collected mosquitoes by a monitoring tool adapted from a microbial detection array","volume":"85","author":"Martin","year":"2019","unstructured":"Martin\n E,\n \n \n Borucki\n MK,\n \n \n Thissen\n J,\n \n \n Garcia-Luna\n S,\n \n \n Hwang\n M,\n \n \n Wise de Valdez\n M.\n \n \n 2019.\n\t\t\t\t\tMosquito-borne viruses and insect-specific viruses revealed in field-collected mosquitoes by a monitoring tool adapted from a microbial detection array.\n\t\t\t\t\tAppl Environ Microbiol85:\n\t\t\t\t\te01202\u2013\n\t\t\t\t\t01219"},{"key":"i8756-971X-36-4-227-Pavela1","series-title":"Acta Trop","first-page":"236","article-title":"Plant extracts for developing mosquito larvicides: from laboratory to the field, with insights on the modes of action","volume":"193","author":"Pavela","year":"2019","unstructured":"Pavela\n R,\n \n \n Maggi\n F,\n \n \n Iannarelli\n R,\n \n \n Benelli\n G.\n \n \n 2019.\n\t\t\t\t\tPlant extracts for developing mosquito larvicides: from laboratory to the field, with insights on the modes of action.\n\t\t\t\t\tActa Trop193:\n\t\t\t\t\t236\u2013\n\t\t\t\t\t271."},{"key":"i8756-971X-36-4-227-PerezLopez1","series-title":"Pak J Pharm Sci","first-page":"1911","article-title":"Essential oils from Zanthoxylum fagara Wild Lime, Ruta chalepensis L. and Thymus vulgaris L.: composition and activity against Aedes aegypti larvae","volume":"28","author":"P\u00e9rez L\u00f3pez","year":"2015","unstructured":"P\u00e9rez L\u00f3pez\n LA,\n \n \n de la Torre\n YC,\n \n \n Cirio\n AT,\n \n \n de Torres\n NW,\n \n \n Flores Su\u00e1rez\n AE,\n \n \n Aranda\n RS.\n \n \n 2015.\n\t\t\t\t\tEssential oils from Zanthoxylum fagara Wild Lime, Ruta chalepensis L. and Thymus vulgaris L.: composition and activity against Aedes aegypti larvae.\n\t\t\t\t\tPak J Pharm Sci28:\n\t\t\t\t\t1911\u2013\n\t\t\t\t\t1915."},{"key":"i8756-971X-36-4-227-Polsomboon1","series-title":"J Am Mosq Control Assoc","first-page":"513","article-title":"Behavioral responses of catnip (Nepeta cataria) by two species of mosquitoes, Aedes aegypti and Anopheles harrisoni, in Thailand","volume":"24","author":"Polsomboon","year":"2008","unstructured":"Polsomboon\n S,\n \n \n Grieco\n JP,\n \n \n Achee\n NL,\n \n \n Chauhan\n KR,\n \n \n Tanasinchayakul\n S,\n \n \n Pothikasikorn\n J,\n \n \n Chareonviriyaphap\n T.\n \n \n 2008.\n\t\t\t\t\tBehavioral responses of catnip (Nepeta cataria) by two species of mosquitoes, Aedes aegypti and Anopheles harrisoni, in Thailand.\n\t\t\t\t\tJ Am Mosq Control Assoc24:\n\t\t\t\t\t513\u2013\n\t\t\t\t\t519."},{"key":"i8756-971X-36-4-227-Reichert1","series-title":"Sci Rep","first-page":"1524","article-title":"Repellency assessment of Nepeta cataria essential oils and isolated nepetalactones on Aedes aegypti","volume":"9","author":"Reichert","year":"2019","unstructured":"Reichert\n W,\n \n \n Ejercito\n J,\n \n \n Guda\n T,\n \n \n Dong\n X,\n \n \n Wu\n Q,\n \n \n Ray\n A,\n \n \n Simon\n JE.\n \n \n 2019.\n\t\t\t\t\tRepellency assessment of Nepeta cataria essential oils and isolated nepetalactones on Aedes aegypti.\n\t\t\t\t\tSci Rep9:\n\t\t\t\t\t1524\u2013\n\t\t\t\t\t1532."},{"key":"i8756-971X-36-4-227-Roh1","series-title":"Pest Manage Sci","first-page":"405","article-title":"Spatial repellency, antifeedant activity and toxicity of three medium chain fatty acids and their methyl esters of coconut fatty acid against stable flies","volume":"76","author":"Roh","year":"2020","unstructured":"Roh\n GH,\n \n \n Zhou\n XJ,\n \n \n Wang\n YS,\n \n \n Cermak\n SC,\n \n \n Kenar\n JA,\n \n \n Lehmann\n A,\n \n \n Han\n BY,\n \n \n Taylor\n DB,\n \n \n Zeng\n XP,\n \n \n Park\n CG,\n \n \n Brewer\n GJ,\n \n \n Zhu\n JJ.\n \n \n 2020.\n\t\t\t\t\tSpatial repellency, antifeedant activity and toxicity of three medium chain fatty acids and their methyl esters of coconut fatty acid against stable flies.\n\t\t\t\t\tPest Manage Sci76:\n\t\t\t\t\t405\u2013\n\t\t\t\t\t414."},{"key":"i8756-971X-36-4-227-Sathantriphop1","series-title":"J Vector Ecol","first-page":"318","article-title":"The effects of plant essential oils on escape response and mortality rate of Aedes aegypti and Anopheles minimus","volume":"40","author":"Sathantriphop","year":"2015","unstructured":"Sathantriphop\n S,\n \n \n Achee\n NL,\n \n \n Sanguanpong\n U,\n \n \n Chareonviriyaphap\n T.\n \n \n 2015.\n\t\t\t\t\tThe effects of plant essential oils on escape response and mortality rate of Aedes aegypti and Anopheles minimus.\n\t\t\t\t\tJ Vector Ecol40:\n\t\t\t\t\t318\u2013\n\t\t\t\t\t326."},{"key":"i8756-971X-36-4-227-WHO1","series-title":"Guidelines for laboratory and field testing of mosquito larvicides","year":"2005","unstructured":"WHO [World Health Organization].\n 2005.\n\t\t\t\t\tGuidelines for laboratory and field testing of mosquito larvicides.\n\t\t\t\t\tGeneva, Switzerland:\n\t\t\t\t\tWorld Health Organization."},{"key":"i8756-971X-36-4-227-WittingBissinger1","series-title":"J Med Entomol","first-page":"891","article-title":"Novel arthropod repellent, BioUD, is an efficacious alternative to deet","volume":"45","author":"Witting-Bissinger","year":"2008","unstructured":"Witting-Bissinger\n BE,\n \n \n Stumpf\n CF,\n \n \n Donohue\n KV,\n \n \n Apperson\n CS,\n \n \n Roe\n RM.\n \n \n 2008.\n\t\t\t\t\tNovel arthropod repellent, BioUD, is an efficacious alternative to deet.\n\t\t\t\t\tJ Med Entomol45:\n\t\t\t\t\t891\u2013\n\t\t\t\t\t898."},{"key":"i8756-971X-36-4-227-Zhu2","series-title":"Sci Rep","first-page":"14053","article-title":"Better than DEET repellent compounds derived from coconut oil","volume":"8","author":"Zhu","year":"2018","unstructured":"Zhu\n JW,\n \n \n Cermak\n SC,\n \n \n Kenar\n JA,\n \n \n Brewer\n G,\n \n \n Haynes\n KF,\n \n \n Boxler\n D,\n \n \n Baker\n PD,\n \n \n Wang\n D,\n \n \n Wang\n C,\n \n \n Li\n AY,\n \n \n Xue\n RD,\n \n \n Shen\n Y,\n \n \n Wang\n F,\n \n \n Agramonte\n NM,\n \n \n Bernier\n UR,\n \n \n de Oliveira Filho\n JG,\n \n \n Borges\n LMF,\n \n \n Friesen\n K,\n \n \n Taylor\n DB.\n \n \n 2018.\n\t\t\t\t\tBetter than DEET repellent compounds derived from coconut oil.\n\t\t\t\t\tSci Rep8:\n\t\t\t\t\t14053."},{"key":"i8756-971X-36-4-227-Zhu1","series-title":"J Am Mosq Control Assoc","first-page":"515","article-title":"Adult repellency and larvicidal activity of five plant essential oils against mosquitoes","volume":"22","author":"Zhu","year":"2006","unstructured":"Zhu\n JW,\n \n \n Zeng\n X,\n \n \n Ma\n Y,\n \n \n Liu\n T,\n \n \n Qian\n K,\n \n \n Han\n Y,\n \n \n Xue\n S,\n \n \n Tucker\n B,\n \n \n Schultz\n G,\n \n \n Coats\n J,\n \n \n Rowley\n W,\n \n \n Zhang\n A.\n \n \n 2006.\n\t\t\t\t\tAdult repellency and larvicidal activity of five plant essential oils against mosquitoes.\n\t\t\t\t\tJ Am Mosq Control Assoc22:\n\t\t\t\t\t515\u2013\n\t\t\t\t\t522."}],"container-title":["Journal of the American Mosquito Control Association"],"original-title":[],"link":[{"URL":"https:\/\/jamca.kglmeridian.com\/view\/journals\/moco\/36\/4\/article-p227.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jamca\/article-pdf\/36\/4\/227\/2774457\/i8756-971x-36-4-227.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jamca.kglmeridian.com\/downloadpdf\/journals\/moco\/36\/4\/article-p227.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jamca.kglmeridian.com\/downloadpdf\/journals\/moco\/36\/4\/article-p227.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:40:23Z","timestamp":1747356023000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamca.kglmeridian.com\/view\/journals\/moco\/36\/4\/article-p227.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":19,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.2987\/20-6916.1","relation":{},"ISSN":["8756-971X"],"issn-type":[{"value":"8756-971X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]}}}