{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:04:25Z","timestamp":1783901065885,"version":"3.55.0"},"reference-count":0,"publisher":"GSC Online Press","issue":"2","content-domain":{"domain":["www.gsconlinepress.com"],"crossmark-restriction":false},"short-container-title":["GSC Adv. Res. Rev."],"abstract":"<jats:p>Vitamin D deficiency affects canines and humans alike. Athletes are a particularly high-risk group. Further research regarding optimal intake and supplementation is needed to establish the parameters of vitamin D status in both humans and canines and to create a physiologically-relevant definition for vitamin D sufficiency. The objectives of this study were to (1) compare 25-OHD (25-hydroxy vitamin D) levels in sled dogs before and after receiving a diet supplemented with wild Alaskan salmon and (2) correlate biomarkers associated with vitamin D metabolism to 25-OHD levels in sled dogs. Plasma samples from 14 working sled dogs between 10 months and 7 years of age were collected before and after a 4-week supplementation with \u00bb0.45 kg of salmon\/day. Samples were analyzed using enzyme-linked immunosorbent assays (ELISA) for parathyroid hormone and vitamin D binding protein (DBP); 25-OHD levels were measured via radioimmunoassay. 25-OHD and DBP in sled dogs significantly increased after a 4-week supplementation with salmon (P=0.0011 and 0.0367, respectively). Additional variations in 25-OHD were observed when separated by sex (P=0.0404) and age (P&lt;0.0001). 57% of the dogs were deficient prior to the salmon supplementation and 14% at the completion of the study. Wild Alaskan salmon is one of the few food sources that provide appreciable amounts of vitamin D. A 4-week salmon supplementation in sled dogs was sufficient to improve 25-OHD concentrations in most sled dogs in this study. Confounding factors such as age and sex affect circulating 25-OHD levels.<\/jats:p>","DOI":"10.30574\/gscarr.2024.18.2.0036","type":"journal-article","created":{"date-parts":[[2024,2,24]],"date-time":"2024-02-24T23:58:40Z","timestamp":1708819120000},"page":"395-401","update-policy":"https:\/\/doi.org\/10.30574\/gscarr.ourcrossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Wild Alaskan salmon supplementation increases 25-OHD levels in sled dogs"],"prefix":"10.30574","volume":"18","author":[{"family":"Kali Ann Striker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Scott Painter Jerome","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Scott Painter Jerome","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Mari H\u00f8e-Raitto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Laura Kay Falkenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Lawrence Kevin Duffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Kriya Lee Dunlap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"12033","published-online":{"date-parts":[[2024,2,28]]},"container-title":["GSC Advanced Research and Reviews"],"original-title":[],"link":[{"URL":"https:\/\/gsconlinepress.com\/journals\/gscarr\/content\/wild-alaskan-salmon-supplementation-increases-25-ohd-levels-sled-dogs","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T23:04:34Z","timestamp":1783897474000},"score":1,"resource":{"primary":{"URL":"https:\/\/gscarr.gsconlinepress.com\/node\/938"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,28]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2,28]]}},"URL":"https:\/\/doi.org\/10.30574\/gscarr.2024.18.2.0036","relation":{},"ISSN":["2582-4597"],"issn-type":[{"value":"2582-4597","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,28]]}}}