{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:55:24Z","timestamp":1775094924035,"version":"3.50.1"},"reference-count":43,"publisher":"American Association for Laboratory Animal Science","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>Lymphatic filariasis is a mosquito-borne parasitic infection affecting an estimated 51.4 million people. <jats:italic>Brugia malayi<\/jats:italic> and <jats:italic>Brugia pahangi<\/jats:italic> are used in research because common nonprimate research species such as Mongolian gerbils (<jats:italic>Meriones unguiculatus<\/jats:italic>), cats (<jats:italic>Felis catus<\/jats:italic>), and dogs (<jats:italic>Canis familiaris<\/jats:italic>) can maintain the life cycle of these species of filarial nematodes. Although overall care and management of animals infected with <jats:italic>Brugia<\/jats:italic> spp. is relatively straightforward, there are some unique challenges and special considerations that must be addressed when managing a research colony infected with these parasites. In this review, we discuss our experience, share insight into biosafety and clinical management, and describe the expected clinical signs associated with <jats:italic>Brugia<\/jats:italic> infection in gerbils, cats, and dogs.<\/jats:p>","DOI":"10.30802\/aalas-cm-24-034","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T01:08:01Z","timestamp":1719450481000},"page":"142-147","source":"Crossref","is-referenced-by-count":3,"title":["An Overview of Management Considerations for Mongolian Gerbils (Meriones unguiculatus), Cats (Felis catus), and Dogs (Canis familiaris) as Hosts for Brugia Infection"],"prefix":"10.30802","volume":"74","author":[{"given":"Catherine A","family":"Chambers","sequence":"first","affiliation":[{"name":"Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia;"},{"name":"University Research Animal Resources, Office of Research, University of Georgia, Athens, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher C","family":"Evans","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia;"},{"name":"Filariasis Research Reagent Resource Center, Department of Infectious Diseases, University of Georgia, Athens, Georgia; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianni A","family":"Campellone","sequence":"additional","affiliation":[{"name":"Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia;"},{"name":"University Research Animal Resources, Office of Research, University of Georgia, Athens, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary A","family":"McCrackin","sequence":"additional","affiliation":[{"name":"Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia;"},{"name":"University Research Animal Resources, Office of Research, University of Georgia, Athens, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew R","family":"Moorhead","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia;"},{"name":"Filariasis Research Reagent Resource Center, Department of Infectious Diseases, University of Georgia, Athens, Georgia; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leanne C","family":"Alworth","sequence":"additional","affiliation":[{"name":"Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia;"},{"name":"Office of Animal Care and Use, Office of Research, University of Georgia, Athens, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"12258","reference":[{"key":"bib1","series-title":"Int J Parasitol","first-page":"677","article-title":"A simple method for isolation of Brugia pahangi and Brugia malayi microfilariae","volume":"4","author":"AhHS","year":"1974","unstructured":"AhHS, McCallJW, ThompsonPE. 1974. 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