{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T02:05:49Z","timestamp":1780365949143,"version":"3.54.1"},"reference-count":56,"publisher":"American Association for Laboratory Animal Science","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Some mice demonstrate excessive food-grinding behaviors in which food pellets are broken down into crumbs (orts). This is considered abnormal behavior and is undesirable in a research environment, as it is thought to potentially be a stereotypic behavior suggestive of a negative welfare state in these animals. Further, food grinding often necessitates more frequent food and bedding changes. Research outcomes may also be affected if investigators do not exclude food losses due to grinding when measuring food consumption. We hypothesized some mice may excessively grind food in part to expend energy and access to a running wheel would contribute to a reduction in food grinding. Total daily food usage (the combined weight of food consumption and ort production) was measured for 40 d in CD-1 mice that exhibited food grinding. Median daily food usage was compared 10 d before, 20 d during, and 10 d after access to a running wheel. Additional cages of similar food-grinding mice that did not have access to a running wheel were monitored during the same period for comparison. A significant reduction in food usage was observed in 8 out of the 20 d in which mice had access to a running wheel compared with controls (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). This reduction was significantly less than the median daily food usage before and after the running wheels were available (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.01). Food usage significantly increased sharply in the 3 d following removal of the running wheel compared with controls during the same period (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). A positive correlation between relative humidity and median daily food usage was observed (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). Despite fluctuations in relative humidity, providing a running wheel effectively reduced excessive food-grinding behavior.\n                  <\/jats:p>","DOI":"10.30802\/aalas-jaalas-24-040","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T21:05:40Z","timestamp":1723669540000},"page":"504-512","source":"Crossref","is-referenced-by-count":2,"title":["Voluntary Wheel Running as an Effective Intervention in the Management of Excessive Food Usage in CD-1 Mice (Mus musculus)"],"prefix":"10.30802","volume":"63","author":[{"given":"Alexis M E","family":"Skurnack","sequence":"first","affiliation":[{"name":"Division of Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn P","family":"Lane","sequence":"additional","affiliation":[{"name":"Division of Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma;"},{"name":"Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori","family":"Garman","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy L","family":"Burke","sequence":"additional","affiliation":[{"name":"Office of Animal Welfare Assurance, Vice President for Research, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy R","family":"Williams","sequence":"additional","affiliation":[{"name":"Division of Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma;"},{"name":"Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeline L","family":"Budda","sequence":"additional","affiliation":[{"name":"Office of Animal Welfare Assurance, Vice President for Research, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; and"},{"name":"Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"12258","reference":[{"key":"bib1","series-title":"Behav Brain Res","first-page":"43","article-title":"Effects of exercise and enrichment on behaviour in CD-1 mice","volume":"342","author":"Aujnarain AB","year":"2018","unstructured":"Aujnarain AB, Luo OD, Taylor N, Lai JKY, Foster JA. 2018. Effects of exercise and enrichment on behaviour in CD-1 mice. Behav Brain Res 342:43\u201350."},{"key":"bib2","series-title":"Front Vet Sci","first-page":"1207332","article-title":"Structural enrichment for laboratory mice: Exploring the effects of novelty and complexity","volume":"10","author":"Bohn L","year":"2023","unstructured":"Bohn L, Bierbaum L, Kastner N, von Kortzfleisch VT, Kaiser S, Sachser N, Richter SH. 2023. Structural enrichment for laboratory mice: Exploring the effects of novelty and complexity. Front Vet Sci 10:1207332."},{"key":"bib3","series-title":"Sci Rep","first-page":"1791","article-title":"Digestibility of crude nutrients and minerals in C57Bl\/6J and CD1 mice fed a pelleted lab rodent diet","volume":"14","author":"Boswald LF","year":"2024","unstructured":"Boswald LF, Matzek D, Popper B. 2024. Digestibility of crude nutrients and minerals in C57Bl\/6J and CD1 mice fed a pelleted lab rodent diet. Sci Rep 14:1791."},{"key":"bib4","series-title":"Lab Anim","first-page":"298","article-title":"The extent and function of \u2018food grinding\u2019 in the laboratory mouse (Mus musculus)","volume":"44","author":"Cameron KM","year":"2010","unstructured":"Cameron KM, Speakman JR. 2010. The extent and function of \u2018food grinding\u2019 in the laboratory mouse (Mus musculus). Lab Anim 44:298\u2013304."},{"key":"bib5","series-title":"J Exp Biol","first-page":"242","article-title":"Nonshivering thermogenesis and its adequate measurement in metabolic studies","volume":"214","author":"Cannon B","year":"2011","unstructured":"Cannon B, Nedergaard J. 2011. Nonshivering thermogenesis and its adequate measurement in metabolic studies. J Exp Biol 214:242\u2013253."},{"key":"bib6","series-title":"Physiol Behav","first-page":"86","article-title":"Effects of voluntary exercise on spontaneous physical activity and food consumption in mice: Results from an artificial selection experiment","volume":"149","author":"Copes LE","year":"2015","unstructured":"Copes LE, Schutz H, Dlugosz EM, Acosta W, Chappell MA, Garland T Jr. 2015. Effects of voluntary exercise on spontaneous physical activity and food consumption in mice: Results from an artificial selection experiment. Physiol Behav 149:86\u201394."},{"key":"bib7","series-title":"PLoS One","first-page":"e0291347","article-title":"Daily replacement of very high-fat diet stabilizes food intake and improves mouse welfare by ensuring food quality","volume":"18","author":"Cordeira J","year":"2023","unstructured":"Cordeira J. 2023. Daily replacement of very high-fat diet stabilizes food intake and improves mouse welfare by ensuring food quality. PLoS One 18:e0291347."},{"key":"bib8","series-title":"Animals (Basel)","first-page":"3424","article-title":"Effect of food restriction on food grinding in Brandt\u2019s voles","volume":"13","author":"Dai X","year":"2023","unstructured":"Dai X, Han YX, Shen QY, Tang H, Cheng LZ, Yang FP, Wei WH, Yang SM. 2023. Effect of food restriction on food grinding in Brandt\u2019s voles. Animals (Basel) 13:3424."},{"key":"bib9","series-title":"Physiol Behav","first-page":"130","article-title":"A review of seasonal\/circannual effects of laboratory rodent behavior","volume":"119","author":"Ferguson SA","year":"2013","unstructured":"Ferguson SA, Maier KL. 2013. A review of seasonal\/circannual effects of laboratory rodent behavior. Physiol Behav 119:130\u2013136."},{"key":"bib10","series-title":"Lab Anim","first-page":"241","article-title":"Influence of diet pellet hardness and particle size on food utilization by mice, rats and hamsters","volume":"11","author":"Ford DJ","year":"1977","unstructured":"Ford DJ. 1977. Influence of diet pellet hardness and particle size on food utilization by mice, rats and hamsters. Lab Anim 11:241\u2013246."},{"key":"bib11","series-title":"ILAR J","first-page":"106","article-title":"Stereotypies and other abnormal repetitive behaviors: Potential impact on validity, reliability, and replicability of scientific outcomes","volume":"46","author":"Garner JP","year":"2005","unstructured":"Garner JP. 2005. Stereotypies and other abnormal repetitive behaviors: Potential impact on validity, reliability, and replicability of scientific outcomes. ILAR J 46:106\u2013117."},{"key":"bib12","series-title":"Physiol Behav","first-page":"55","article-title":"The mouse thermoregulatory system: Its impact on translating biomedical data to humans","volume":"179","author":"Gordon CJ","year":"2017","unstructured":"Gordon CJ. 2017. The mouse thermoregulatory system: Its impact on translating biomedical data to humans. Physiol Behav 179:55\u201366."},{"key":"bib13","series-title":"PLoS One","first-page":"e0261876","article-title":"Evaluation of different types of enrichment\u2014Their usage and effect on home cage behavior in female mice","volume":"16","author":"Hobbiesiefken U","year":"2021","unstructured":"Hobbiesiefken U, Mieske P, Lewejohann L, Diederich K. 2021. Evaluation of different types of enrichment\u2014Their usage and effect on home cage behavior in female mice. PLoS One 16:e0261876."},{"key":"bib14","series-title":"Guide for the care and use of laboratory animals","year":"2011","unstructured":"Institute for Laboratory Animal Research. 2011. Guide for the care and use of laboratory animals, 8th ed. Washington (DC): National Academies Press."},{"key":"bib15","series-title":"Physiol Behav","first-page":"375","article-title":"Food wasting by house mice: Variation among individuals, families, and genetic lines","volume":"80","author":"Koteja P","year":"2003","unstructured":"Koteja P, Carter PA, Swallow JG, Garland T Jr. 2003. Food wasting by house mice: Variation among individuals, families, and genetic lines. Physiol Behav 80:375\u2013383."},{"key":"bib16","series-title":"Braz J Med Biol Res","first-page":"e7830","article-title":"Voluntary wheel running: Patterns and physiological effects in mice","volume":"52","author":"Manzanares G","year":"2018","unstructured":"Manzanares G, Brito-da-Silva G, Gandra PG. 2018. Voluntary wheel running: Patterns and physiological effects in mice. Braz J Med Biol Res 52:e7830."},{"key":"bib17","series-title":"Proc Natl Acad Sci USA","first-page":"6127","article-title":"\u201cControl\u201d laboratory rodents are metabolically morbid: Why it matters","volume":"107","author":"Martin B","year":"2010","unstructured":"Martin B, Ji S, Maudsley S, Mattson MP. 2010. \u201cControl\u201d laboratory rodents are metabolically morbid: Why it matters. Proc Natl Acad Sci USA 107:6127\u20136133."},{"key":"bib18","series-title":"Proc Natl Acad Sci USA","first-page":"12550","article-title":"Metabolic rate and environmental productivity: Well-provisioned animals evolved to run and idle fast","volume":"98","author":"Mueller P","year":"2001","unstructured":"Mueller P, Diamond J. 2001. Metabolic rate and environmental productivity: Well-provisioned animals evolved to run and idle fast. Proc Natl Acad Sci USA 98:12550\u201312554."},{"key":"bib19","series-title":"Nutrient requirements of laboratory animals","year":"1995","unstructured":"National Research Council Subcommittee on Laboratory Animal Nutrition. 1995. Nutrient requirements of laboratory animals, 4th revised ed. Washington (DC): National Academies Press."},{"key":"bib20","article-title":"What is the heat index?","unstructured":"National Weather Service. [Internet]. What is the heat index? Available at: https:\/\/www.weather.gov\/ama\/heatindex. Accessed 24 May 2024."},{"key":"bib21","article-title":"Climate of Oklahoma","year":"2024","unstructured":"Oklahoma Climatological Survey. [Internet]. 2024. Climate of Oklahoma. Available at: https:\/\/climate.ok.gov\/index.php\/site\/page\/climate_of_oklahoma. Accessed 24 May 2024."},{"key":"bib22","series-title":"Comp Biochem Physiol A Physiol","first-page":"119","article-title":"Food sorting by collard lemming (Dicrostonyx groenlandicus) and prairie voles (Microtus ochrogaster): A cautionary note for digestibility studies","volume":"116","author":"Peterson J","year":"1997","unstructured":"Peterson J, Wunder BA. 1997. Food sorting by collard lemming (Dicrostonyx groenlandicus) and prairie voles (Microtus ochrogaster): A cautionary note for digestibility studies. Comp Biochem Physiol A Physiol 116:119\u2013124."},{"key":"bib23","series-title":"Lab Anim","first-page":"312","article-title":"Can seeds help mice with the daily grind?","volume":"47","author":"Pritchett-Corning KR","year":"2013","unstructured":"Pritchett-Corning KR, Keefe R, Garner JP, Gaskill BN. 2013. Can seeds help mice with the daily grind? Lab Anim 47:312\u2013315."},{"key":"bib24","series-title":"Horm Behav","first-page":"104556","article-title":"Housing conditions modulate spontaneous physical activity, feeding behavior, aerobic running capacity and adiposity in C57BL\/6J mice","volume":"115","author":"Scariot PPM","year":"2019","unstructured":"Scariot PPM, Manchado-Gobatto FB, Prolla TA, Masselli Dos Reis IG, Gobatto CA. 2019. Housing conditions modulate spontaneous physical activity, feeding behavior, aerobic running capacity and adiposity in C57BL\/6J mice. Horm Behav 115:104556."},{"key":"bib25","series-title":"Nat Methods","first-page":"57","article-title":"A guide to analysis of mouse energy metabolism","volume":"9","author":"Tschop MH","year":"2011","unstructured":"Tschop MH, Speakman JR, Arch JR, Auwerx J, Bruning JC, Chan L, Eckel RH, et al. 2011. A guide to analysis of mouse energy metabolism. Nat Methods 9:57\u201363."},{"key":"bib26","series-title":"J Cell Biol","first-page":"893","article-title":"Big mammals have big (or slow) cells","volume":"176","author":"Wells WA","year":"2007","unstructured":"Wells WA. 2007. Big mammals have big (or slow) cells. J Cell Biol 176:893."},{"key":"bib27","series-title":"Int J Hyg Environ Health","first-page":"376","article-title":"Indoor air humidity, air quality, and health\u2014An overview","volume":"221","author":"Wolkoff P","year":"2018","unstructured":"Wolkoff P. 2018. Indoor air humidity, air quality, and health\u2014An overview. Int J Hyg Environ Health 221:376\u2013390."},{"key":"bib28","series-title":"J Appl Behav Anal","first-page":"529","article-title":"A retrospective analysis of stereotypy: Applicability of the behavioral subtyping model","volume":"55","author":"Wunderlich KL","year":"2022","unstructured":"Wunderlich KL, Hemstreet R, Best L. 2022. A retrospective analysis of stereotypy: Applicability of the behavioral subtyping model. J Appl Behav Anal 55:529\u2013546."},{"key":"bib1","series-title":"Behav Brain Res","first-page":"43","article-title":"Effects of exercise and enrichment on behaviour in CD-1 mice","volume":"342","author":"Aujnarain AB","year":"2018","unstructured":"Aujnarain AB, Luo OD, Taylor N, Lai JKY, Foster JA. 2018. Effects of exercise and enrichment on behaviour in CD-1 mice. Behav Brain Res 342:43\u201350."},{"key":"bib2","series-title":"Front Vet Sci","first-page":"1207332","article-title":"Structural enrichment for laboratory mice: Exploring the effects of novelty and complexity","volume":"10","author":"Bohn L","year":"2023","unstructured":"Bohn L, Bierbaum L, Kastner N, von Kortzfleisch VT, Kaiser S, Sachser N, Richter SH. 2023. Structural enrichment for laboratory mice: Exploring the effects of novelty and complexity. Front Vet Sci 10:1207332."},{"key":"bib3","series-title":"Sci Rep","first-page":"1791","article-title":"Digestibility of crude nutrients and minerals in C57Bl\/6J and CD1 mice fed a pelleted lab rodent diet","volume":"14","author":"Boswald LF","year":"2024","unstructured":"Boswald LF, Matzek D, Popper B. 2024. Digestibility of crude nutrients and minerals in C57Bl\/6J and CD1 mice fed a pelleted lab rodent diet. Sci Rep 14:1791."},{"key":"bib4","series-title":"Lab Anim","first-page":"298","article-title":"The extent and function of \u2018food grinding\u2019 in the laboratory mouse (Mus musculus)","volume":"44","author":"Cameron KM","year":"2010","unstructured":"Cameron KM, Speakman JR. 2010. The extent and function of \u2018food grinding\u2019 in the laboratory mouse (Mus musculus). Lab Anim 44:298\u2013304."},{"key":"bib5","series-title":"J Exp Biol","first-page":"242","article-title":"Nonshivering thermogenesis and its adequate measurement in metabolic studies","volume":"214","author":"Cannon B","year":"2011","unstructured":"Cannon B, Nedergaard J. 2011. Nonshivering thermogenesis and its adequate measurement in metabolic studies. J Exp Biol 214:242\u2013253."},{"key":"bib6","series-title":"Physiol Behav","first-page":"86","article-title":"Effects of voluntary exercise on spontaneous physical activity and food consumption in mice: Results from an artificial selection experiment","volume":"149","author":"Copes LE","year":"2015","unstructured":"Copes LE, Schutz H, Dlugosz EM, Acosta W, Chappell MA, Garland T Jr. 2015. Effects of voluntary exercise on spontaneous physical activity and food consumption in mice: Results from an artificial selection experiment. Physiol Behav 149:86\u201394."},{"key":"bib7","series-title":"PLoS One","first-page":"e0291347","article-title":"Daily replacement of very high-fat diet stabilizes food intake and improves mouse welfare by ensuring food quality","volume":"18","author":"Cordeira J","year":"2023","unstructured":"Cordeira J. 2023. Daily replacement of very high-fat diet stabilizes food intake and improves mouse welfare by ensuring food quality. PLoS One 18:e0291347."},{"key":"bib8","series-title":"Animals (Basel)","first-page":"3424","article-title":"Effect of food restriction on food grinding in Brandt\u2019s voles","volume":"13","author":"Dai X","year":"2023","unstructured":"Dai X, Han YX, Shen QY, Tang H, Cheng LZ, Yang FP, Wei WH, Yang SM. 2023. Effect of food restriction on food grinding in Brandt\u2019s voles. Animals (Basel) 13:3424."},{"key":"bib9","series-title":"Physiol Behav","first-page":"130","article-title":"A review of seasonal\/circannual effects of laboratory rodent behavior","volume":"119","author":"Ferguson SA","year":"2013","unstructured":"Ferguson SA, Maier KL. 2013. A review of seasonal\/circannual effects of laboratory rodent behavior. Physiol Behav 119:130\u2013136."},{"key":"bib10","series-title":"Lab Anim","first-page":"241","article-title":"Influence of diet pellet hardness and particle size on food utilization by mice, rats and hamsters","volume":"11","author":"Ford DJ","year":"1977","unstructured":"Ford DJ. 1977. Influence of diet pellet hardness and particle size on food utilization by mice, rats and hamsters. Lab Anim 11:241\u2013246."},{"key":"bib11","series-title":"ILAR J","first-page":"106","article-title":"Stereotypies and other abnormal repetitive behaviors: Potential impact on validity, reliability, and replicability of scientific outcomes","volume":"46","author":"Garner JP","year":"2005","unstructured":"Garner JP. 2005. Stereotypies and other abnormal repetitive behaviors: Potential impact on validity, reliability, and replicability of scientific outcomes. ILAR J 46:106\u2013117."},{"key":"bib12","series-title":"Physiol Behav","first-page":"55","article-title":"The mouse thermoregulatory system: Its impact on translating biomedical data to humans","volume":"179","author":"Gordon CJ","year":"2017","unstructured":"Gordon CJ. 2017. The mouse thermoregulatory system: Its impact on translating biomedical data to humans. Physiol Behav 179:55\u201366."},{"key":"bib13","series-title":"PLoS One","first-page":"e0261876","article-title":"Evaluation of different types of enrichment\u2014Their usage and effect on home cage behavior in female mice","volume":"16","author":"Hobbiesiefken U","year":"2021","unstructured":"Hobbiesiefken U, Mieske P, Lewejohann L, Diederich K. 2021. Evaluation of different types of enrichment\u2014Their usage and effect on home cage behavior in female mice. PLoS One 16:e0261876."},{"key":"bib14","series-title":"Guide for the care and use of laboratory animals","year":"2011","unstructured":"Institute for Laboratory Animal Research. 2011. Guide for the care and use of laboratory animals, 8th ed. Washington (DC): National Academies Press."},{"key":"bib15","series-title":"Physiol Behav","first-page":"375","article-title":"Food wasting by house mice: Variation among individuals, families, and genetic lines","volume":"80","author":"Koteja P","year":"2003","unstructured":"Koteja P, Carter PA, Swallow JG, Garland T Jr. 2003. Food wasting by house mice: Variation among individuals, families, and genetic lines. Physiol Behav 80:375\u2013383."},{"key":"bib16","series-title":"Braz J Med Biol Res","first-page":"e7830","article-title":"Voluntary wheel running: Patterns and physiological effects in mice","volume":"52","author":"Manzanares G","year":"2018","unstructured":"Manzanares G, Brito-da-Silva G, Gandra PG. 2018. Voluntary wheel running: Patterns and physiological effects in mice. Braz J Med Biol Res 52:e7830."},{"key":"bib17","series-title":"Proc Natl Acad Sci USA","first-page":"6127","article-title":"\u201cControl\u201d laboratory rodents are metabolically morbid: Why it matters","volume":"107","author":"Martin B","year":"2010","unstructured":"Martin B, Ji S, Maudsley S, Mattson MP. 2010. \u201cControl\u201d laboratory rodents are metabolically morbid: Why it matters. Proc Natl Acad Sci USA 107:6127\u20136133."},{"key":"bib18","series-title":"Proc Natl Acad Sci USA","first-page":"12550","article-title":"Metabolic rate and environmental productivity: Well-provisioned animals evolved to run and idle fast","volume":"98","author":"Mueller P","year":"2001","unstructured":"Mueller P, Diamond J. 2001. Metabolic rate and environmental productivity: Well-provisioned animals evolved to run and idle fast. Proc Natl Acad Sci USA 98:12550\u201312554."},{"key":"bib19","series-title":"Nutrient requirements of laboratory animals","year":"1995","unstructured":"National Research Council Subcommittee on Laboratory Animal Nutrition. 1995. Nutrient requirements of laboratory animals, 4th revised ed. Washington (DC): National Academies Press."},{"key":"bib20","article-title":"What is the heat index?","unstructured":"National Weather Service. [Internet]. What is the heat index? Available at: https:\/\/www.weather.gov\/ama\/heatindex. Accessed 24 May 2024."},{"key":"bib21","article-title":"Climate of Oklahoma","year":"2024","unstructured":"Oklahoma Climatological Survey. [Internet]. 2024. Climate of Oklahoma. Available at: https:\/\/climate.ok.gov\/index.php\/site\/page\/climate_of_oklahoma. Accessed 24 May 2024."},{"key":"bib22","series-title":"Comp Biochem Physiol A Physiol","first-page":"119","article-title":"Food sorting by collard lemming (Dicrostonyx groenlandicus) and prairie voles (Microtus ochrogaster): A cautionary note for digestibility studies","volume":"116","author":"Peterson J","year":"1997","unstructured":"Peterson J, Wunder BA. 1997. Food sorting by collard lemming (Dicrostonyx groenlandicus) and prairie voles (Microtus ochrogaster): A cautionary note for digestibility studies. Comp Biochem Physiol A Physiol 116:119\u2013124."},{"key":"bib23","series-title":"Lab Anim","first-page":"312","article-title":"Can seeds help mice with the daily grind?","volume":"47","author":"Pritchett-Corning KR","year":"2013","unstructured":"Pritchett-Corning KR, Keefe R, Garner JP, Gaskill BN. 2013. Can seeds help mice with the daily grind? Lab Anim 47:312\u2013315."},{"key":"bib24","series-title":"Horm Behav","first-page":"104556","article-title":"Housing conditions modulate spontaneous physical activity, feeding behavior, aerobic running capacity and adiposity in C57BL\/6J mice","volume":"115","author":"Scariot PPM","year":"2019","unstructured":"Scariot PPM, Manchado-Gobatto FB, Prolla TA, Masselli Dos Reis IG, Gobatto CA. 2019. Housing conditions modulate spontaneous physical activity, feeding behavior, aerobic running capacity and adiposity in C57BL\/6J mice. Horm Behav 115:104556."},{"key":"bib25","series-title":"Nat Methods","first-page":"57","article-title":"A guide to analysis of mouse energy metabolism","volume":"9","author":"Tschop MH","year":"2011","unstructured":"Tschop MH, Speakman JR, Arch JR, Auwerx J, Bruning JC, Chan L, Eckel RH, et al. 2011. A guide to analysis of mouse energy metabolism. Nat Methods 9:57\u201363."},{"key":"bib26","series-title":"J Cell Biol","first-page":"893","article-title":"Big mammals have big (or slow) cells","volume":"176","author":"Wells WA","year":"2007","unstructured":"Wells WA. 2007. Big mammals have big (or slow) cells. J Cell Biol 176:893."},{"key":"bib27","series-title":"Int J Hyg Environ Health","first-page":"376","article-title":"Indoor air humidity, air quality, and health\u2014An overview","volume":"221","author":"Wolkoff P","year":"2018","unstructured":"Wolkoff P. 2018. Indoor air humidity, air quality, and health\u2014An overview. Int J Hyg Environ Health 221:376\u2013390."},{"key":"bib28","series-title":"J Appl Behav Anal","first-page":"529","article-title":"A retrospective analysis of stereotypy: Applicability of the behavioral subtyping model","volume":"55","author":"Wunderlich KL","year":"2022","unstructured":"Wunderlich KL, Hemstreet R, Best L. 2022. A retrospective analysis of stereotypy: Applicability of the behavioral subtyping model. J Appl Behav Anal 55:529\u2013546."}],"container-title":["Journal of the American Association for Laboratory Animal Science"],"original-title":[],"link":[{"URL":"https:\/\/aalas.kglmeridian.com\/view\/journals\/72010024\/63\/5\/article-p504.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aalas.kglmeridian.com\/downloadpdf\/journals\/72010024\/63\/5\/article-p504.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/aalas.kglmeridian.com\/downloadpdf\/journals\/72010024\/63\/5\/article-p504.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:42:22Z","timestamp":1780364542000},"score":1,"resource":{"primary":{"URL":"https:\/\/aalas.kglmeridian.com\/view\/journals\/72010024\/63\/5\/article-p504.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":56,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.30802\/aalas-jaalas-24-040","relation":{},"ISSN":["1559-6109"],"issn-type":[{"value":"1559-6109","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]}}}