{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T08:51:09Z","timestamp":1776329469819,"version":"3.50.1"},"reference-count":0,"publisher":"Universidad Nacional de C\u00f3rdoba","issue":"2","license":[{"start":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T00:00:00Z","timestamp":1588723200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Fac Cien Med Univ Nac Cordoba"],"abstract":"<jats:p>Introduction\r\nThe use of local references or standard for neonatal studies still requires their validation through indicators of morbidity and mortality. Objective: evaluate the performance of the INTERGROWTH-21st Project (IG-21) standard and a commonly used Argentinian reference (Urquia) by examining the differences in the frequency of growth phenotypes, and the associated neonatal morbidity and mortality.\r\nMethods: Retrospective cohort study of all singleton live-births from Sarda Maternity Hospital (Buenos Aires, Argentina) between 33 and 42 gestational age, using information obtained from a Perinatal Surveillance System (Agustina) dataset between 1996-2001 (n = 25948). Phenotypes small- and large-for-gestational age, stunting and waisting and a composite of neonatal morbidity\/mortality (CNMM) were contrasted between the IG-21 standard and Urquia reference.\r\nResults: the Urquia 3rd centile value was lower than IG-21 before 37 weeks, but then it surpassed IG-21 until term. Among Sarda , 2.3%, 5.9% and 8.9 were &lt;3rd, &lt;10th and &gt;97th centile, respectively, under the IG-21 standard, while 3.7%, 10.1% and 8.4% were &lt;3rd, &lt;10th and &gt;97th centile, respectively, under the Urquia reference. Stunting and waisting were 16.1% and 0.9%, respectively under IG-21. The IG-21 detection rates of CNMM showed that 28.5%, 19.6% and 8.5% occurred among weight&lt;3rd,&lt;10th and &gt;97th centile, respectively, while 21.8%, 14.2% and 8.0%\u00a0 occurred among &lt;3rd, &lt;10th and &gt;97th centile under the Urquia criteria. Newborn weight &lt;3rd,&lt;10th and &gt;97th\u00a0 centile under IG-21 showed higher neonatal CNMM risk compared with Urquia reference.\r\nConclusions: The IG-21 standard identified a higher risk of neonatal morbidity and mortality than the Urquia reference.<\/jats:p>","DOI":"10.31053\/1853.0605.v77.n2.28064","type":"journal-article","created":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T10:57:30Z","timestamp":1592564250000},"page":"86-93","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the INTERGROWTH-21st project newborn standard for neonatal phenotypes and neonatal morbidity and mortality"],"prefix":"10.31053","volume":"77","author":[{"given":"Carlos","family":"Grandi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6095-7080","authenticated-orcid":false,"given":"Mariana","family":"Del Pino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1019-3654","authenticated-orcid":false,"given":"Davi","family":"Casale Aragon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2933-6125","authenticated-orcid":false,"given":"Livia","family":"Dos Santos Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2677-5600","authenticated-orcid":false,"given":"Viviane","family":"Cunha Cardoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"12333","published-online":{"date-parts":[[2020,5,6]]},"container-title":["Revista de la Facultad de Ciencias M\u00e9dicas de C\u00f3rdoba"],"original-title":[],"link":[{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/28064\/29617","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/28064\/29868","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/28064\/29868","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T10:57:30Z","timestamp":1592564250000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/view\/28064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,6]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,5,20]]}},"URL":"https:\/\/doi.org\/10.31053\/1853.0605.v77.n2.28064","relation":{},"ISSN":["1853-0605","0014-6722"],"issn-type":[{"value":"1853-0605","type":"electronic"},{"value":"0014-6722","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5,6]]}}}