{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T08:49:42Z","timestamp":1776329382109,"version":"3.50.1"},"reference-count":0,"publisher":"Universidad Nacional de C\u00f3rdoba","issue":"3","license":[{"start":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T00:00:00Z","timestamp":1663286400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Fac Cien Med Univ Nac Cordoba"],"abstract":"<jats:p>Introducci\u00f3n: La colestasis extrahep\u00e1tica producida por opi\u00e1ceos es una entidad sumamente infrecuente de la cual solo se registran reportes de casos en la literatura. M\u00e9todos: Se presenta el caso cl\u00ednico de una paciente que desarroll\u00f3 dolor abdominal y colestasis luego del consumo prolongado de morfina a altas dosis, tratada por cirug\u00eda laparosc\u00f3pica. Resultados: La paciente evoluciona favorablemente en el postoperatorio sin bilirragia y es dada de alta al quinto d\u00eda con valores de bilirrubina dentro de los par\u00e1metros normales. Conclusi\u00f3n: El s\u00edndrome de disfunci\u00f3n del esf\u00ednter de Oddi secundario a consumo por tiempo prolongado de opioides es una entidad muy infrecuente. Sin embargo, debe sospecharse ante cuadros de colestasis extrahep\u00e1ticas en los que no se observe litiasis ni tumores y en pacientes con consumo de opi\u00e1ceos a altas dosis por tiempo prolongado ya sea por adicci\u00f3n o por tratamiento del dolor cr\u00f3nico.<\/jats:p>","DOI":"10.31053\/1853.0605.v79.n3.33738","type":"journal-article","created":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T12:29:21Z","timestamp":1663676961000},"page":"277-279","source":"Crossref","is-referenced-by-count":1,"title":["Una causa infrecuente de colestasis extrahep\u00e1tica: colestasis inducida por morfina"],"prefix":"10.31053","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5755-0367","authenticated-orcid":false,"given":"Carlos","family":"Canullan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Cristina","family":"Du Plessis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8283-4268","authenticated-orcid":false,"given":"Pablo","family":"Merchan del Hierro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8283-4268","authenticated-orcid":false,"given":"Bernabe","family":"Quesada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2575-4656","authenticated-orcid":false,"given":"Enrique","family":"Petracchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"12333","published-online":{"date-parts":[[2022,9,16]]},"container-title":["Revista de la Facultad de Ciencias M\u00e9dicas de C\u00f3rdoba"],"original-title":[],"link":[{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/33738\/38800","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/33738\/38800","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T12:29:21Z","timestamp":1663676961000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/view\/33738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,16]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,9,16]]}},"URL":"https:\/\/doi.org\/10.31053\/1853.0605.v79.n3.33738","relation":{},"ISSN":["1853-0605","0014-6722"],"issn-type":[{"value":"1853-0605","type":"electronic"},{"value":"0014-6722","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9,16]]}}}