{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T08:49:45Z","timestamp":1776329385275,"version":"3.50.1"},"reference-count":0,"publisher":"Universidad Nacional de C\u00f3rdoba","issue":"2","license":[{"start":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T00:00:00Z","timestamp":1688083200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Fac Cien Med Univ Nac Cordoba"],"abstract":"<jats:p>Los tumores neuroendocrinos (TNE) primarios de la v\u00eda biliar son extremadamente raros y representan s\u00f3lo el 0.2-2% de todos los TNE gastrointestinales. Dentro del sistema biliar, la v\u00eda biliar principal es el sitio m\u00e1s afectado. Hombre de 28 a\u00f1os con cuadro de 6 meses de evoluci\u00f3n caracterizado por ictericia intermitente, prurito y coluria. Se realiz\u00f3 colangiopancreatoresonancia magn\u00e9tica nuclear, PET-TC y ultrasonido endosc\u00f3pico que concluyeron neoplasia neuroendocrina bien diferenciada. Se realiz\u00f3 resecci\u00f3n completa de la v\u00eda biliar principal con linfadenectom\u00eda del ped\u00edculo hep\u00e1tico con hepaticoyeyunoanastomosis en Y de Roux, sin complicaciones. El paciente curs\u00f3 adecuada evoluci\u00f3n y se encuentra libre de enfermedad. Los tumores neuroendocrinos primarios de la v\u00eda biliar son extremadamente raros, present\u00e1ndose cl\u00ednica y radiol\u00f3gicamente como lesiones similares al colangiocarcinoma perihiliar lo que dificulta el diagn\u00f3stico preoperatorio. Est\u00e1 indicado su tratamiento quir\u00fargico radical. Suelen ser bien diferenciados, siendo el ant\u00edgeno Ki-67 un marcador pron\u00f3stico confiable.<\/jats:p>","DOI":"10.31053\/1853.0605.v80.n2.40368","type":"journal-article","created":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T13:39:05Z","timestamp":1688477945000},"page":"141-144","source":"Crossref","is-referenced-by-count":0,"title":["Tumor neuroendocrino primario del conducto hep\u00e1tico com\u00fan"],"prefix":"10.31053","volume":"80","author":[{"given":"Rodrigo Antonio","family":"Gasque","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noelia","family":"Zaietta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Luj\u00e1n","family":"Del Bueno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julieta","family":"Saenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magal\u00ed","family":"Chahdi Beltrame","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio Gast\u00f3n","family":"Qui\u00f1onez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Juan","family":"Mattera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"12333","published-online":{"date-parts":[[2023,6,30]]},"container-title":["Revista de la Facultad de Ciencias M\u00e9dicas de C\u00f3rdoba"],"original-title":[],"link":[{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/40368\/41731","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/40368\/41192","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/40368\/41731","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T13:39:06Z","timestamp":1688477946000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/view\/40368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,6,30]]}},"URL":"https:\/\/doi.org\/10.31053\/1853.0605.v80.n2.40368","relation":{},"ISSN":["1853-0605","0014-6722"],"issn-type":[{"value":"1853-0605","type":"electronic"},{"value":"0014-6722","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6,30]]}}}