{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T08:51:05Z","timestamp":1776329465915,"version":"3.50.1"},"reference-count":26,"publisher":"Universidad Nacional de C\u00f3rdoba","issue":"3","license":[{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Fac Cien Med Univ Nac Cordoba"],"abstract":"<jats:p>Introduction: Liver cirrhosis is a global public health problem, increasing the risk of hepatocellular carcinoma (HCC), a highly aggressive cancer. Early diagnosis through imaging studies is crucial for timely treatment.\r\nObjective: To describe the clinical and imaging characteristics of patients with cirrhosis and HCC at a tertiary hospital in C\u00f3rdoba, Argentina.\r\nMethods: A retrospective analytical study reviewed the medical records of patients with cirrhosis and\/or HCC who underwent computed tomography (CT) and\/or magnetic resonance imaging (MRI) between 2017 and 2023.\r\nResults: A total of 221 cirrhotic patients were included, 142 (64.3%) of whom were male, with a median: interquartile range 25-75% (n IQR) age of 60: 54-66 years. The etiologies were: alcoholic (30.3%), non-alcoholic steatohepatitis (NASH) (26.2%), hepatitis B (21.7%), hepatitis C (12.2%), and others (9.5%). HCC was diagnosed in 42 (19%) patients. CT was performed on all patients, and MRI on 22 (52.4%). Among patients with HCC, NASH was the most common cause (38.1%). LI-RADS criteria classified 30 (71.4%) patients as LI-RADS-5, while 12 (28.6%) progressed from lower categories. During an 18-month follow-up, 22 (9.95%) cirrhotic patients died.\r\nConclusions: Alcoholic cirrhosis was the leading cause, and HCC was diagnosed in 19% of patients. CT was performed in all HCC patients, and MRI in half. Both modalities demonstrated HCC characteristics in more than 95% of cases. The 18-month mortality was 9.95% in cirrhotic patients and 16% in patients with HCC.<\/jats:p>","DOI":"10.31053\/1853.0605.v82.n3.46375","type":"journal-article","created":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T18:18:04Z","timestamp":1759169884000},"page":"484-504","source":"Crossref","is-referenced-by-count":0,"title":["Caracter\u00edsticas cl\u00ednicas y de imagen en pacientes con cirrosis y carcinoma hepatocelular en un hospital de tercer nivel de C\u00f3rdoba","Clinical and Imaging Features in Patients with Cirrhosis and Hepatocellular Carcinoma at a Tertiary Hospital in C\u00f3rdoba","Caracter\u00edsticas cl\u00ednicas e de imagem em pacientes com cirrose e carcinoma hepatocelular em um hospital terci\u00e1rio de C\u00f3rdoba"],"prefix":"10.31053","volume":"82","author":[{"given":"Virginia","family":"Oliva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Mui\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Orozco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuel Jos\u00e9","family":"Saad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"12333","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. 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