{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T17:24:07Z","timestamp":1783099447978,"version":"3.54.6"},"reference-count":31,"publisher":"Universidad Nacional de C\u00f3rdoba","issue":"2","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Fac Cien Med Univ Nac Cordoba"],"abstract":"<jats:p>Analizar y correlacionar los s\u00edntomas subjetivos de somnolencia diurna, depresi\u00f3n, ansiedad antes y despu\u00e9s del tratamiento con CPAP. Se realiz\u00f3 un estudio retrospectivo, observacional, longitudinal. Se extrajo datos de cuestionarios completados en 3 oportunidades. El primer cuestionario, debi\u00f3 ser entregado en el momento de realizarse una PSG nocturna con oximetr\u00eda diagn\u00f3stica. El segundo y tercero al realizarse PSG nocturna con oximetr\u00eda con titulaci\u00f3n con Auto-CPAP Se utiliz\u00f3 la Escala de Somnolencia de Epworth, Escala de Autoreporte de Ansiedad y el Inventario de Depresi\u00f3n de Beck. Resultados: Encontramos disminuci\u00f3n significativa en la Escala de Somnolencia de Ewporth a lo largo de los a\u00f1os, pero no encontramos diferencias en la Escala para ansiedad p=0,45 y ni para depresi\u00f3n p=0,52. Conclusi\u00f3n: El an\u00e1lisis de trastornos del \u00e1nimo y somnolencia diurna en pacientes en seguimiento por uso de CPAP demostr\u00f3 que la somnolencia diurna se redujo con el uso del dispositivo, pero no fue as\u00ed con los marcadores de trastornos del humor. Los m\u00e9dicos deben ser conscientes de nuestros hallazgos para comprender la magnitud del beneficio que se puede obtener de la terapia con CPAP sobre la somnolencia y ayudar en la toma de decisiones en la atenci\u00f3n m\u00e9dica.<\/jats:p>","DOI":"10.31053\/1853.0605.v83.n2.50007","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:03:01Z","timestamp":1782846181000},"page":"e50007","source":"Crossref","is-referenced-by-count":0,"title":["Evoluci\u00f3n de somnolencia y de los s\u00edntomas afectivos en pacientes con apnea obstructiva del sue\u00f1o tratados con presi\u00f3n positiva continua sobre la v\u00eda a\u00e9rea","Evolu\u00e7\u00e3o da sonol\u00eancia e sintomas afetivos em pacientes com apneia obstrutiva do sono tratados com Press\u00e3o Positiva Cont\u00ednua nas Vias A\u00e9reas","Evolution of daytime sleepiness and affective symptoms in patients with obstructive sleep apnea treated with Continuous Positive Airway Pressure"],"prefix":"10.31053","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3977-2457","authenticated-orcid":false,"given":"Stella Maris","family":"Valiensi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agust\u00edn","family":"Folgueira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"12333","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. Brodie KD, Goldberg AN. Obstructive Sleep Apnea: A Surgeon's Perspective. Med Clin North Am. 2021 Sep;105(5):885-900. doi: 10.1016\/j.mcna.2021.05.010.","DOI":"10.1016\/j.mcna.2021.05.010"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2. Dragonieri S, Bikov A. Obstructive Sleep Apnea: A View from the Back Door. Medicina (Kaunas). 2020 Apr 25;56(5):208. doi: 10.3390\/medicina56050208.","DOI":"10.3390\/medicina56050208"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Peces-Barba Romero G, L\u00f3pez-Campos Bodineau JL, Mediano O, Vaquero P, R\u00edos Cort\u00e9s AT. Gu\u00eda SEPAR de las terapias respiratorias domiciliarias, 2020. Open Respir Arch. 2020;2(1):32-62. doi: 10.1016\/j.opresp.2020.01.004.","DOI":"10.1016\/j.opresp.2020.01.004"},{"key":"ref3","unstructured":"4. Hobzova M, Prasko J, Vanek J, Ociskova M, Genzor S, Holubova M, Grambal A, Latalova K. Depression and obstructive sleep apnea. Neuro Endocrinol Lett. 2017 Oct;38(5):343-352."},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Chiner E, Arriero JM, Signes-Costa J, Marco J, Fuentes I. Validaci\u00f3n de la versi\u00f3n espa\u00f1ola del test de somnolencia Epworth en pacientes con s\u00edndrome de apnea de sue\u00f1o. Arch Bronconeumol. 1999 Oct;35(9):422-7. doi: 10.1016\/s0300-2896(15)30037-5.","DOI":"10.1016\/S0300-2896(15)30037-5"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991 Dec;14(6):540-5. doi: 10.1093\/sleep\/14.6.540.","DOI":"10.1093\/sleep\/14.6.540"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7. Dunstan DA, Scott N. Norms for Zung's Self-rating Anxiety Scale. BMC Psychiatry. 2020 Feb 28;20(1):90. doi: 10.1186\/s12888-019-2427-6.","DOI":"10.1186\/s12888-019-2427-6"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"8. Zung WW. A rating instrument for anxiety disorders. Psychosomatics. 1971 Nov-Dec;12(6):371-9. doi: 10.1016\/S0033-3182(71)71479-0.","DOI":"10.1016\/S0033-3182(71)71479-0"},{"key":"ref8","unstructured":"9. Brenlla ME, Rodr\u00edguez CM. Adaptaci\u00f3n argentina del Inventario de Depresi\u00f3n de Beck (BDI-II). Buenos Aires: Paid\u00f3s; 2006."},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10. Penley JA, Wiebe JS, Nwosu A. Psychometric properties of the Spanish Beck Depression Inventory-II in a medical sample. Psychol Assess. 2003 Dec;15(4):569-77. doi: 10.1037\/1040-3590.15.4.569.","DOI":"10.1037\/1040-3590.15.4.569"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"11. Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ, Nunez CM, Patel SR, Penzel T, P\u00e9pin JL, Peppard PE, Sinha S, Tufik S, Valentine K, Malhotra A. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med. 2019 Aug;7(8):687-698. doi: 10.1016\/S2213-2600(19)30198-5.","DOI":"10.1016\/S2213-2600(19)30198-5"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"12. Jordan AS, McSharry DG, Malhotra A. Adult obstructive sleep apnoea. Lancet. 2014 Feb 22;383(9918):736-47. doi: 10.1016\/S0140-6736(13)60734-5.","DOI":"10.1016\/S0140-6736(13)60734-5"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13. Macey PM, Woo MA, Kumar R, Cross RL, Harper RM. Relationship between obstructive sleep apnea severity and sleep, depression and anxiety symptoms in newly-diagnosed patients. PLoS One. 2010 Apr 16;5(4):e10211. doi: 10.1371\/journal.pone.0010211.","DOI":"10.1371\/journal.pone.0010211"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"14. Sharafkhaneh A, Giray N, Richardson P, Young T, Hirshkowitz M. Association of psychiatric disorders and sleep apnea in a large cohort. Sleep. 2005 Nov;28(11):1405-11. doi: 10.1093\/sleep\/28.11.1405.","DOI":"10.1093\/sleep\/28.11.1405"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"15. Bardwell WA, Ancoli-Israel S, Dimsdale JE. Types of coping strategies are associated with increased depressive symptoms in patients with obstructive sleep apnea. Sleep. 2001 Dec 15;24(8):905-9. doi: 10.1093\/sleep\/24.8.905.","DOI":"10.1093\/sleep\/24.8.905"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16. Jean-Louis G, Zizi F, Clark LT, Brown CD, McFarlane SI. Obstructive sleep apnea and cardiovascular disease: role of the metabolic syndrome and its components. J Clin Sleep Med. 2008 Jun 15;4(3):261-72.","DOI":"10.5664\/jcsm.27191"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"17. Campos-Rodr\u00edguez F, Reina-Gonz\u00e1lez A, Reyes-N\u00fa\u00f1ez N, Beiztegui-Sillero A, Almeida-Gonz\u00e1lez C, Pe\u00f1a-Gri\u00f1\u00e1n N. Caracter\u00edsticas cardiovasculares y cl\u00ednicas de los pacientes con apneas obstructivas del sue\u00f1o sin somnolencia diurna excesiva. Arch Bronconeumol. 2010 Nov;46(11):594-9. doi: 10.1016\/j.arbres.2010.07.011.","DOI":"10.1016\/j.arbres.2010.07.011"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"18. Pepperell JC, Ramdassingh-Dow S, Crosthwaite N, Mullins R, Jenkinson C, Stradling JR, Davies RJ. Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial. Lancet. 2002 Jan 19;359(9302):204-10. doi: 10.1016\/S0140-6736(02)07445-7.","DOI":"10.1016\/S0140-6736(02)07445-7"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"19. Punjabi NM, Caffo BS, Goodwin JL, Gottlieb DJ, Newman AB, O'Connor GT, Rapoport DM, Redline S, Resnick HE, Robbins JA, Shahar E, Unruh ML, Samet JM. Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med. 2009 Aug;6(8):e1000132. doi: 10.1371\/journal.pmed.1000132.","DOI":"10.1371\/journal.pmed.1000132"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"20. Benjafield AV, Pepin JL, Cistulli PA, Wimms A, Lavergne F, Sert Kuniyoshi FH, Munson SH, Schuler B, Reddy Badikol S, Wolfe KC, Willes L, Kelly C, Kendzerska T, Johnson DA, Heinzer R, Lee CH, Malhotra A; medXcloud Group. Positive airway pressure therapy and all-cause and cardiovascular mortality in people with obstructive sleep apnoea: a systematic review and meta-analysis of randomised controlled trials and confounder-adjusted, non-randomised controlled studies. Lancet Respir Med. 2025 May;13(5):403-413. doi: 10.1016\/S2213-2600(25)00002-5.","DOI":"10.1016\/S2213-2600(25)00002-5"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"21. Patil SP, Billings ME, Bourjeily G, Collop NA, Gottlieb DJ, Johnson KG, Kimoff RJ, Pack AI. Long-term health outcomes for patients with obstructive sleep apnea: placing the Agency for Healthcare Research and Quality report in context-a multisociety commentary. J Clin Sleep Med. 2024 Jan 1;20(1):135-149. doi: 10.5664\/jcsm.10832.","DOI":"10.5664\/jcsm.10832"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"22. Gay P, Weaver T, Loube D, Iber C; Positive Airway Pressure Task Force; Standards of Practice Committee; American Academy of Sleep Medicine. Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults. Sleep. 2006 Mar;29(3):381-401. doi: 10.1093\/sleep\/29.3.381.","DOI":"10.1093\/sleep\/29.3.381"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"23. Sawyer AM, Gooneratne NS, Marcus CL, Ofer D, Richards KC, Weaver TE. A systematic review of CPAP adherence across age groups: clinical and empiric insights for developing CPAP adherence interventions. Sleep Med Rev. 2011 Dec;15(6):343-56. doi: 10.1016\/j.smrv.2011.01.003.","DOI":"10.1016\/j.smrv.2011.01.003"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"24. Stuck BA, Leitzbach S, Maurer JT. Effects of continuous positive airway pressure on apnea-hypopnea index in obstructive sleep apnea based on long-term compliance. Sleep Breath. 2012 Jun;16(2):467-71. doi: 10.1007\/s11325-011-0527-8.","DOI":"10.1007\/s11325-011-0527-8"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"25. Means MK, Lichstein KL, Edinger JD, Taylor DJ, Durrence HH, Husain AM, Aguillard RN, Radtke RA. Changes in depressive symptoms after continuous positive airway pressure treatment for obstructive sleep apnea. Sleep Breath. 2003 Mar;7(1):31-42. doi: 10.1007\/s11325-003-0031-x.","DOI":"10.1007\/s11325-003-0031-x"},{"key":"ref25","unstructured":"26. Feng J, Chen BY, Chiang AA. Significance of depression in obstructive sleep apnea patients and the relationship between the comorbidity and continuous positive airway pressure treatment. Chin Med J (Engl). 2010 Jun;123(12):1596-602."},{"key":"ref26","doi-asserted-by":"publisher","unstructured":"27. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993 Apr 29;328(17):1230-5. doi: 10.1056\/NEJM199304293281704.","DOI":"10.1056\/NEJM199304293281704"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"28. Corcho-Mej\u00eda DC, Vel\u00e1squez-Su\u00e1rez JM, Escobar-C\u00f3rdoba F. Apnea obstructiva del sue\u00f1o y trastornos psiqui\u00e1tricos. Rev. Chil. neuro-psiquiatr. 2012 Dic;50(4):265-272. doi: 10.4067\/S0717-92272012000400009.","DOI":"10.4067\/S0717-92272012000400009"},{"key":"ref28","doi-asserted-by":"publisher","unstructured":"29. Gupta MA, Simpson FC. Obstructive sleep apnea and psychiatric disorders: a systematic review. J Clin Sleep Med. 2015 Jan 15;11(2):165-75. doi: 10.5664\/jcsm.4466.","DOI":"10.5664\/jcsm.4466"},{"key":"ref29","doi-asserted-by":"publisher","unstructured":"30. Vanek J, Prasko J, Genzor S, Ociskova M, Kantor K, Holubova M, Slepecky M, Nesnidal V, Kolek A, Sova M. Obstructive sleep apnea, depression and cognitive impairment. Sleep Med. 2020 Aug;72:50-58. doi: 10.1016\/j.sleep.2020.03.017.","DOI":"10.1016\/j.sleep.2020.03.017"},{"key":"ref30","doi-asserted-by":"publisher","unstructured":"31. Balk EM, Adam GP, Cao W, Bhuma MR, D'Ambrosio C, Trikalinos TA. Long-term effects on clinical event, mental health, and related outcomes of CPAP for obstructive sleep apnea: a systematic review. J Clin Sleep Med. 2024 Jun 1;20(6):895-909. doi: 10.5664\/jcsm.11030.","DOI":"10.5664\/jcsm.11030"}],"container-title":["Revista de la Facultad de Ciencias M\u00e9dicas de C\u00f3rdoba"],"original-title":[],"link":[{"URL":"http:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/50007\/53609","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/50007\/53610","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/download\/50007\/53610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T17:07:37Z","timestamp":1783098457000},"score":1,"resource":{"primary":{"URL":"http:\/\/revistas.unc.edu.ar\/index.php\/med\/article\/view\/50007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,22]]},"references-count":31,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,6,30]]}},"URL":"https:\/\/doi.org\/10.31053\/1853.0605.v83.n2.50007","relation":{},"ISSN":["1853-0605","0014-6722"],"issn-type":[{"value":"1853-0605","type":"electronic"},{"value":"0014-6722","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,22]]}}}