{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T13:16:59Z","timestamp":1783430219753,"version":"3.54.6"},"reference-count":77,"publisher":"IMR Press","issue":"3","license":[{"start":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T00:00:00Z","timestamp":1782604800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Alpha Psychiatry"],"abstract":"<jats:p>Background: Scalp acupuncture and brain stimulation techniques, such as transcranial electrical stimulation, have shown promise in the management of mental disorders. However, the identification of precise stimulation targets remains a critical bottleneck. Pinpointing brain regions associated with mental disorders is essential for optimizing the efficacy of these scalp-based therapies. Methods: Using Neurosynth Compose, we performed large-scale coordinate-based meta-analyses to identify potential targets for nine mental disorders: schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, obsessive-compulsive disorder, post-traumatic stress disorder, insomnia, autism spectrum disorder, and attention deficit hyperactivity disorder. The identified brain clusters were projected onto the scalp surface and spatially integrated with standard acupoints, and the electroencephalography (EEG) 10\u201320 system to define accessible intervention sites. Results: The analyses successfully delineated scalp targets for each of the nine investigated disorders. These findings largely corroborated existing clinical protocols while also suggesting novel regions as potential therapeutic targets. The results revealed both disorder-specific targets and cortical areas implicated across multiple psychiatric conditions. Notably, the dorsolateral and ventrolateral prefrontal cortices, middle temporal gyrus, and inferior parietal lobule emerged as critical overlapping targets, offering potential avenues for scalp acupuncture and brain stimulation in comorbid mental disorders. Conclusions: We propose refined, evidence-based protocols for scalp acupuncture and brain stimulation. These findings may advance precision-targeted neuromodulation strategies and support the development of novel therapeutic approaches in psychiatric care.<\/jats:p>","DOI":"10.31083\/ap45940","type":"journal-article","created":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:42:51Z","timestamp":1783428171000},"source":"Crossref","is-referenced-by-count":0,"title":["Potential Targets for Scalp Acupuncture and Brain Stimulation in Mental Disorders: Evidence From Large-Scale Meta-Analyses"],"prefix":"10.31083","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9403-9805","authenticated-orcid":true,"given":"Yuanyuan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuefeng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binlong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Acupuncture, Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences, 100053 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyi","family":"Yu","sequence":"additional","affiliation":[{"name":"Acupuncture-Moxibustion and Tuina School, Chengdu University of Traditional Chinese Medicine, 611137 Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine, Capital Medical University, 100069 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Cao","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Beijing University of Chinese Medicine, 100029 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyuan","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2744-6067","authenticated-orcid":true,"given":"Jian","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2026,6,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Zheng Y, Qin Z, Tsoi B, Shen J, Zhang ZJ. 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