{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:25:53Z","timestamp":1785882353464,"version":"3.56.0"},"reference-count":20,"publisher":"IMR Press","issue":"2","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"General Research Project of Zhejiang Provincial Education Department","award":["Y202454726"],"award-info":[{"award-number":["Y202454726"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br. J. Hosp. Med. (Lond)"],"abstract":"<jats:p>Aims\/Background: Young and middle-aged patients undergoing maintenance hemodialysis (MHD) experience significant physical impairment and psychological stress, resulting in reduced levels of subjective well-being. Therefore, this study aimed to assess the subjective well-being of this population and to identify its influencing factors, thereby informing the clinical development of targeted nursing strategies. Methods: Clinical data were collected from 220 young and middle-aged MHD patients at the Blood Purification Center of the Second Affiliated Hospital, Zhejiang University School of Medicine between April 2024 and April 2025. General demographic and clinical characteristics, along with scores from relevant assessment scales, were collected. The factors influencing subjective well-being were analyzed in this patient cohort. Results: The mean General Well-Being (GWB) scale score among these patients was 62.44 \u00b1 3.12. Statistically significant differences were observed across education level, per capita monthly family income, self-care ability, self-management ability, symptom distress, financial burden to the family, and social support (p &lt; 0.05). Multiple linear regression analysis indicated that education, per capita monthly family income, self-care ability, self-management ability, symptom distress, financial burden on the family, and social support were significant predictors of subjective well-being among young and middle-aged MHD patients (p &lt; 0.05). Conclusion: The subjective well-being of young and middle-aged MHD patients remains at a moderate level and is influenced by factors such as education level, per capita monthly family income, self-care ability, self-management ability, symptom distress, financial burden on the family, and social support. Nursing care interventions should be designed and implemented based on these factors to improve the overall well-being of this patient group.<\/jats:p>","DOI":"10.31083\/bjhm50724","type":"journal-article","created":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T13:29:12Z","timestamp":1772285352000},"source":"Crossref","is-referenced-by-count":1,"title":["Analysis of Factors Influencing Subjective Well-Being in Young and Middle-Aged Patients Undergoing Maintenance Hemodialysis"],"prefix":"10.31083","volume":"87","author":[{"given":"Muying","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009 Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bibi","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009 Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009 Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Wan J, Lin J, Wang W, Fu L, Zhang W, Liu J, et al. Relationship between Dialysate Bicarbonate Concentration and All-Cause Mortality in Hemodialysis Patients. Kidney & Blood Pressure Research. 2023; 48: 460\u2013467.","DOI":"10.1159\/000531267"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Gu Q, Wu TF, Chen JF. Evidence-based practice of dietary management in maintenance hemodialysis patients. Chinese Journal of Nursing. 2021; 56: 1485\u20131489.  (In Chinese)","DOI":"10.3761\/j.issn.0254-1769.2021.10.007"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Huang B, Lai B, Xu L, Wang Y, Cao Y, Yan P, et al. Low employment and low willingness of being reemployed in Chinese working-age maintained hemodialysis patients. Renal Failure. 2017; 39: 607\u2013612.","DOI":"10.1080\/0886022X.2017.1361834"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Zhang L, Zhao MH, Zuo L, Wang Y, Yu F, Zhang H, et al. China Kidney Disease Network (CK-NET) 2016 Annual Data Report. 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Complementary Therapies in Clinical Practice. 2023; 53: 101793.","DOI":"10.1016\/j.ctcp.2023.101793"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Weisbord SD, Fried LF, Arnold RM, Rotondi AJ, Fine MJ, Levenson DJ, et al. Development of a symptom assessment instrument for chronic hemodialysis patients: the Dialysis Symptom Index. Journal of Pain and Symptom Management. 2004; 27: 226\u2013240.","DOI":"10.1016\/j.jpainsymman.2003.07.004"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Wen J, Fang Y, Su Z, Cai J, Chen Z. Mental health and its influencing factors of maintenance hemodialysis patients: a semi-structured interview study. BMC Psychology. 2023; 11: 84.","DOI":"10.1186\/s40359-023-01109-2"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Pretto CR, Rosa MBCD, Dezordi CM, Benetti SAW, Colet CDF, Stumm EMF. Depression and chronic renal patients on hemodialysis: associated factors. Revista Brasileira De Enfermagem. 2020; 73: e20190167.  (In Portuguese, English)","DOI":"10.1590\/0034-7167-2019-0167"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"Ma Y, Yu H, Sun H, Li M, Li L, Qin M. Economic burden of maintenance hemodialysis patients\u2019 families in Nanchong and its influencing factors. Annals of Palliative Medicine. 2020; 9: 3877\u20133884.","DOI":"10.21037\/apm-20-1787"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"Hao J, Wang Y, Wang Y, Zhang J, Gao J, Kang L, et al. Analysis of influencing factors on quality of life in patients with chronic kidney disease undergoing maintenance haemodialysis. Heliyon. 2024; 10: e25817.","DOI":"10.1016\/j.heliyon.2024.e25817"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"Peng M, Cai X, Wang Q, Li Z, Cao R, Guan B, et al. Effects of Visualized Health Education Based on Health Belief Model on Self-Management of Patients Undergoing Maintenance Hemodialysis. 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