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AI has demonstrated considerable success in screening and diagnosis of a range of cancer types, including breast, colorectal, and skin cancer, but challenges with specificity and false-positive rates remain. Within radiology and histopathology, AI shows promise in identifying cancers and augmenting clinician performance. Natural language processing and AI-driven clinical documentation tools can expedite diagnosis by reducing administrative burden and extracting clinically meaningful data from unstructured records. Additionally, AI models using unimodal and multimodal data can improve patient prognostication and risk stratification. Despite these advances, challenges relating to deployment, bias, interpretability, accountability and real-world efficacy persist. Prospective validation and careful implementation are required to ensure safe, equitable, and effective adoption of AI in cancer diagnostics.<\/jats:p>","DOI":"10.31083\/bjhm51300","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T07:59:43Z","timestamp":1785398383000},"source":"Crossref","is-referenced-by-count":0,"title":["The Use of Artificial Intelligence in Cancer Diagnosis"],"prefix":"10.31083","volume":"87","author":[{"given":"Arka","family":"Banerjee","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, SE1 7EH London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6167-9879","authenticated-orcid":true,"given":"Daphne Theresa","family":"Chia","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6060-1487","authenticated-orcid":true,"given":"Kai Yuen","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Tiwari A, Mishra S, Kuo TR. 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