{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:39:39Z","timestamp":1753889979275,"version":"3.41.2"},"reference-count":15,"publisher":"IMR Press","issue":"6","license":[{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"PHARMA-HUB T4-AN-04 Project","award":["N\u00b0E63C22001680001"],"award-info":[{"award-number":["N\u00b0E63C22001680001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Integr. Neurosci."],"DOI":"10.31083\/j.jin2306115","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T09:26:52Z","timestamp":1718357212000},"source":"Crossref","is-referenced-by-count":2,"title":["A Hundred Faces for a Unique Disorder: Hereditary Spastic Paraplegia"],"prefix":"10.31083","volume":"23","author":[{"given":"Piero","family":"Pavone","sequence":"first","affiliation":[{"name":"Section of Pediatrics and Child Neuropsychiatry, Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaele","family":"Falsaperla","sequence":"first","affiliation":[{"name":"General Pediatrics, Pediatric Acute and Emergency Unit, \u201cPoliclinico-San Marco\" University Hospital, University of Catania, 95124 Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agata","family":"Polizzi","sequence":"first","affiliation":[{"name":"Department of Educational Science, University of Catania, 95124 Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2024,6,13]]},"reference":[{"key":"ref1","unstructured":"Opal P, Ajroud-Driss S. Hereditary spastic paraplegia. UpTodate Wolters Kluwer. Available at: https:\/\/medilib.ir\/uptodate\/show\/14152 (Accessed: 10 Jan 2024)."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Martinello C, Panza E, Orlacchio A. Hereditary spastic paraplegias proteome: common pathways and pathogenetic mechanisms. Expert Review of Proteomics. 2023; 20: 171\u2013188.","DOI":"10.1080\/14789450.2023.2260952"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Fink JK. The hereditary spastic paraplegias. Handbook of Clinical Neurology. 2023; 196: 59\u201388.","DOI":"10.1016\/B978-0-323-98817-9.00022-3"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Elsayed LEO, Eltazi IZ, Ahmed AE, Stevanin G. Insights into Clinical, Genetic, and Pathological Aspects of Hereditary Spastic Paraplegias: A Comprehensive Overview. Frontiers in Molecular Biosciences. 2021; 8: 690899.","DOI":"10.3389\/fmolb.2021.690899"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Str\u00fcmpell A. Beitrage zur Pathologie des R\u00fcckenmarks. Archiv f\u00fcr Psychiatrie und Nervenkrankheiten. 1880; 10: 676\u2013717.","DOI":"10.1007\/BF02224539"},{"key":"ref6","unstructured":"Lorrain M. Contribution \u00e0 l\u2019\u00e9tude de la Parapl\u00e9gie Spasmodique Familiale. Hachette Livre: Paris, France. 2016."},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Meyyazhagan A, Orlacchio A. Hereditary Spastic Paraplegia: An Update. International Journal of Molecular Sciences. 2022; 23: 1697.","DOI":"10.3390\/ijms23031697"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"McDermott C, White K, Bushby K, Shaw P. Hereditary spastic paraparesis: a review of new developments. Journal of Neurology, Neurosurgery, and Psychiatry. 2000; 69: 150\u2013160.","DOI":"10.1136\/jnnp.69.2.150"},{"key":"ref9","unstructured":"Hedera P. Hereditary Spastic Paraplegia Overview. GeneReviews\u00ae [Internet]. 2021; 2: 11."},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Harding AE. Hereditary \u201cpure\u201d spastic paraplegia: a clinical and genetic study of 22 families. Journal of Neurology, Neurosurgery, and Psychiatry. 1981; 44: 871\u2013883.","DOI":"10.1136\/jnnp.44.10.871"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"McLeod JG, Morgan JA, Reye C. Electrophysiological studies in familial spastic paraplegia. Journal of Neurology, Neurosurgery, and Psychiatry. 1977; 40: 611\u2013615.","DOI":"10.1136\/jnnp.40.6.611"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Karle KN, Sch\u00fcle R, Klebe S, Otto S, Frischholz C, Liepelt-Scarfone I, et al. Electrophysiological characterisation of motor and sensory tracts in patients with hereditary spastic paraplegia (HSP). Orphanet Journal of Rare Diseases. 2013; 8: 158.","DOI":"10.1186\/1750-1172-8-158"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Kilic MA, Yildiz EP, Deniz A, Coskun O, Kurekci F, Avci R, et al. A Retrospective Review of 18 Patients With Childhood-Onset Hereditary Spastic Paraplegia, Nine With Novel Variants. Pediatric Neurology. 2024; 152: 189\u2013195.","DOI":"10.1016\/j.pediatrneurol.2024.01.005"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Maccora S, Torrente A, Di Stefano V, Lupica A, Iacono S, Pilati L, et al. Non-pharmacological treatment of hereditary spastic paraplegia: a systematic review. Neurological Sciences. 2024; 45: 963\u2013976.","DOI":"10.1007\/s10072-023-07200-1"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Selcuk Muhtaroglu F, Belgen Kaygisiz B, Usar Incirli S, Kahraman T. Dalfampridine as a promising agent in the management of hereditary spastic paraplegia: A triple-blinded, randomized, placebo-controlled pilot trial. Journal of Clinical Neuroscience. 2023; 117: 136\u2013142.","DOI":"10.1016\/j.jocn.2023.09.026"}],"container-title":["Journal of Integrative Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.imrpress.com\/journal\/JIN\/23\/6\/10.31083\/j.jin2306115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T16:34:23Z","timestamp":1732725263000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/JIN\/23\/6\/10.31083\/j.jin2306115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,13]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024]]}},"alternative-id":["S0219-6352(24)00746-0"],"URL":"https:\/\/doi.org\/10.31083\/j.jin2306115","relation":{},"ISSN":["0219-6352","1757-448X"],"issn-type":[{"type":"print","value":"0219-6352"},{"type":"electronic","value":"1757-448X"}],"subject":[],"published":{"date-parts":[[2024,6,13]]},"article-number":"115"}}