{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T21:29:38Z","timestamp":1790976578888,"version":"4.1.0"},"reference-count":108,"publisher":"IMR Press","issue":"2","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Cardiovasc. Med."],"abstract":"<jats:p>Global diabetes mellitus prevalence is increasing. Metabolic disorders, such as type 2 diabetes, are associated with abnormal cardiac electrophysiology and increased risk of arrhythmias. Patients with both diabetes types (1 and 2) suffer from sudden cardac death (SCD) as a leading cause of mortality. Cardiovascular death is defined as death attributable to cardiovascular disease (CVD) occurring shortly within the symptom onset. This usually arises from life-threatening ventricular tachyarrhythmias that lead to hemodynamic instability, and subsequent shock and death. A variety of pathways have been suggested that link hypoglycaemia to the development of adverse cardiovascular outcomes, including blood coagulation abnormalities, inflammation, endothelial dysfunction and sympathoadrenal responses. We propose a four-step framework for the optimisation of SCD risk factors in diabetic patients, to include: raising awareness to influence health behaviour, provision of screening programs, use of technology within educational programs to improve patient engagement and effective provision of diabetic community teams.<\/jats:p>","DOI":"10.31083\/j.rcm2202038","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T05:11:38Z","timestamp":1625461898000},"source":"Crossref","is-referenced-by-count":19,"title":["Clinical overview of diabetes mellitus as a risk factor for cardiovascular death"],"prefix":"10.31083","volume":"22","author":[{"given":"Eyad","family":"Abuelgasim","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Imperial College London, SW7 2BX London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suleyman","family":"Shah","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Imperial College London, SW7 2BX London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biyaser","family":"Abuelgasim","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Imperial College London, SW7 2BX London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikita","family":"Soni","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Imperial College London, SW7 2BX London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashvin","family":"Thomas","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Imperial College London, SW7 2BX London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Elgasim","sequence":"first","affiliation":[{"name":"University Hospital of Birmingham, B15 2TH Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer","family":"Harky","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, L14 3PE Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"ref1","unstructured":"NCD Risk Factor Collaboration (NCD-RisC). 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