{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:37:16Z","timestamp":1771331836145,"version":"3.50.1"},"reference-count":79,"publisher":"IMR Press","issue":"2","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Cardiovasc. Med."],"abstract":"<jats:p>There has been an apparent association between the risks of complications with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with a history of existing chronic respiratory diseases during the pandemic of coronavirus disease 2019 (COVID-19). SARS-CoV-2 poses a severe risk in cardiopulmonary management. Moreover, chronic respiratory diseases may further amplify the risk of morbidity and mortality among the afflicted population in the pandemic era. The present review outlines the importance of pulmonary rehabilitation (PR) in persons with chronic respiratory diseases (Chronic obstructive pulmonary disease (COPD) and Asthma) during the COVID-19 era. In this context, amongst the population with a pre-existing pulmonary diagnosis who have contracted SARS-CoV-2, following initial medical management and acute recovery, exercise-based pulmonary rehabilitation (PR) may play a crucial role in long-term management and recovery. The energy conservation techniques will play a pragmatic role in PR of mild to moderate severity cases to counter post-COVID-19 fatigue. Moreover, there is also an urgent need to effectively address post-COVID-19 anxiety and depression, affecting the PR delivery system.<\/jats:p>","DOI":"10.31083\/j.rcm2202039","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T05:11:38Z","timestamp":1625461898000},"source":"Crossref","is-referenced-by-count":23,"title":["Revisiting pulmonary rehabilitation during COVID-19 pandemic: a narrative review"],"prefix":"10.31083","volume":"22","author":[{"given":"Snehil","family":"Dixit","sequence":"first","affiliation":[{"name":"Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, 61421 Abha, Kingdom of Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Audrey","family":"Borghi-Silva","sequence":"first","affiliation":[{"name":"Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of Sao Carlos, 13565-905 Sao Carlos, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalyana Chakravarthy","family":"Bairapareddy","sequence":"first","affiliation":[{"name":"College of Health sciences, University of Sharjah, 27272 Sharjah, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Leung JM, Yang CX, Tam A, Shaipanich T, Hackett T, Singhera GK, et al. ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19. European Respiratory Journal. 2020; 55: 2000688.","DOI":"10.1183\/13993003.00688-2020"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Lippi G, Henry BM. Chronic obstructive pulmonary disease is associated with severe coronavirus disease 2019 (COVID-19): COPD and COVID-19. Respiratory Medicine. 2020; 16.","DOI":"10.1016\/j.rmed.2020.105941"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Blumenthal D, Fowler EJ, Abrams M, Collins SR. COVID-19\u2014implications for the health care system. New England Journal of Medicine. 2020; 383: 1483\u20131488.","DOI":"10.1056\/NEJMsb2021088"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Zayet S, Kadiane-Oussou NJ, Lepiller Q, Zahra H, Royer P, Toko L, et al. Clinical features of COVID-19 and influenza: a comparative study on Nord Franche-Comte cluster. Microbes and Infection. 2020; 22: 481\u2013488.","DOI":"10.1016\/j.micinf.2020.05.016"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. Journal of Autoimmunity. 2020; 109: 102433.","DOI":"10.1016\/j.jaut.2020.102433"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Engelkes M, de Ridder MA, Svensson E, Berencsi K, Prieto-Alhambra D, Lapi F, et al. Multinational cohort study of mortality in patients with asthma and severe asthma. Respiratory Medicine. 2020; 165: 105919.","DOI":"10.1016\/j.rmed.2020.105919"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Wu F, Zhou Y, Wang Z, Xie M, Shi Z, Tang Z, et al. Clinical characteristics of COVID-19 infection in chronic obstructive pulmonary disease: a multicenter, retrospective, observational study. Journal of Thoracic Disease. 2020; 12: 1811\u20131823.","DOI":"10.21037\/jtd-20-1914"},{"key":"ref8","unstructured":"2021. Available at: https:\/\/goldcopd.org\/wp-content\/uploads\/2020\/11\/GOLD-REPORT-2021-v1.1-25Nov20_WMV.pdf (Accessed: 4 April 2021)."},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Chang MC, Park Y, Kim B, Park D. Risk factors for disease progression in COVID-19 patients. BMC Infectious Diseases. 2020; 20: 445.","DOI":"10.1186\/s12879-020-05144-x"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Grasselli G, Greco M, Zanella A, Albano G, Antonelli M, Bellani G, et al. Risk factors associated with mortality among patients with COVID-19 in intensive care units in Lombardy, Italy. JAMA Internal Medicine. 2020; 108: 1345\u20131355.","DOI":"10.1001\/jamainternmed.2020.3539"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Celli B, Fabbri LM. Urgent need of a management plan for survivors of COVID-19. European Respiratory Journal. 2020; 55: 2000764.","DOI":"10.1183\/13993003.00764-2020"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Kurtai\u015f Ayt\u00fcr Y. Pulmonary rehabilitation principles in SARS-CoV-2 infection (COVID-19): a guideline for the acute and subacute rehabilitation. Turkish Journal of Physical Medicine and Rehabilitation. 2020; 66: 104\u2013120.","DOI":"10.5606\/tftrd.2020.6444"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Anastasio F, Barbuto S, Scarnecchia E, Cosma P, Fugagnoli A, Rossi G, et al. Medium-term impact of COVID-19 on pulmonary function, functional capacity and quality of life. European Respiratory Journal. 2021. (in press)","DOI":"10.1183\/13993003.04015-2020"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Spagnolo P, Balestro E, Aliberti S, Cocconcelli E, Biondini D, Casa GD, et al. Pulmonary fibrosis secondary to COVID-19: a call to arms? The Lancet Respiratory Medicine. 2020; 8: 750\u2013752.","DOI":"10.1016\/S2213-2600(20)30222-8"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Satia I, Cusack R, Greene JM, O\u2019Byrne PM, Killian KJ, Johnston N. Prevalence and contribution of respiratory viruses in the community to rates of emergency department visits and hospitalizations with respiratory tract infections, chronic obstructive pulmonary disease and Asthma. PLoS ONE. 2020; 15: e0228544.","DOI":"10.1371\/journal.pone.0228544"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Adamopoulos S, Parissis J, Karatzas D, Kroupis C, Georgiadis M, Karavolias G, et al. Physical training modulates proinflammatory cytokines and the soluble Fas\/soluble Fas ligand system in patients with chronic heart failure. Journal of the American College of Cardiology. 2002; 39: 653\u2013663.","DOI":"10.1016\/S0735-1097(01)01795-8"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Wang TJ, Chau B, Lui M, Lam G, Lin N, Humbert S. Physical medicine and rehabilitation and pulmonary rehabilitation for COVID-19. American Journal of Physical Medicine & Rehabilitation. 2020; 99: 769\u2013774.","DOI":"10.1097\/PHM.0000000000001505"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Salisbury H. Helen Salisbury: when will we be well again? British Medical Journal. 2020; 369: 32248536.","DOI":"10.1136\/bmj.m2490"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Zhao Q, Meng M, Kumar R, Wu Y, Huang J, Lian N, et al. The impact of COPD and smoking history on the severity of COVID\u201019: a systemic review and meta\u2010analysis. Journal of Medical Virology. 2020; 92: 1915\u20131921.","DOI":"10.1002\/jmv.25889"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Grasselli G, Tonetti T, Protti A, Langer T, Girardis M, Bellani G, et al. Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study. The Lancet Respiratory Medicine. 2020; 8: 1201\u20131208.","DOI":"10.1016\/S2213-2600(20)30370-2"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Spruit MA, Vercoulen JH, Sprangers MAG, Wouters EFM. Fatigue in COPD: an important yet ignored symptom. The Lancet. Respiratory Medicine. 2017; 5: 542\u2013544.","DOI":"10.1016\/S2213-2600(17)30158-3"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Marques A, J\u00e1come C, Rebelo P, Paix\u00e3o C, Oliveira A, Cruz J, et al. Improving access to community-based pulmonary rehabilitation: 3R protocol for real-world settings with cost-benefit analysis. BMC Public Health. 2019; 19: 676.","DOI":"10.1186\/s12889-019-7045-1"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Zampogna E, Zappa M, Spanevello A, Visca D. Pulmonary rehabilitation and asthma. Frontiers in Pharmacology. 2020; 11: 1\u20136.","DOI":"10.3389\/fphar.2020.00542"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Goodman-Casanova JM, Dura-Perez E, Guzman-Parra J, Cuesta-Vargas A, Mayoral-Cleries F. Telehealth home support during COVID-19 confinement for community-dwelling older adults with mild cognitive impairment or mild dementia: survey study. Journal of Medical Internet Research. 2020; 22: e19434.","DOI":"10.2196\/19434"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Dew A, Bulkeley K, Veitch C, Bundy A, Gallego G, Lincoln M, et al. Addressing the barriers to accessing therapy services in rural and remote areas. Disability and Rehabilitation. 2013; 35: 1564\u20131570.","DOI":"10.3109\/09638288.2012.720346"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Blackstock FC, Evans RA. Rehabilitation in lung diseases: \u2018Education\u2019 component of pulmonary rehabilitation. Respirology. 2019; 24: 863\u2013870.","DOI":"10.1111\/resp.13582"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Jaywant A, Vanderlind WM, Boas SJ, Dickerman AL. Behavioral interventions in acute COVID-19 recovery: a new opportunity for integrated care. General Hospital Psychiatry. 2020; 69: 113\u2013114.","DOI":"10.1016\/j.genhosppsych.2020.07.001"},{"key":"ref28","unstructured":"Askey R. Exploring the benefits of a psychoeducation session for patients with chronic obstructive pulmonary disease (COPD) and co-morbid depression and\/or anxiety. Mental Health. 2020."},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Aldcroft SA, Taylor NF, Blackstock FC, O\u2019Halloran PD. Psychoeducational rehabilitation for health behavior change in coronary artery disease. Journal of Cardiopulmonary Rehabilitation and Prevention. 2011; 31: 273\u2013281.","DOI":"10.1097\/HCR.0b013e318220a7c9"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Folgering H, van Herwaarden C. Pulmonary rehabilitation in asthma and COPD, physiological basics. Respiratory Medicine. 1993; 87: 41\u201344.","DOI":"10.1016\/S0954-6111(06)80353-7"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Strategy G, Obstructive C, Disease P. GOLD (Global Initiative for Chronic Obstructive Lung Disease) 2017. Pneumologie. 2017; 71: 9\u201314.","DOI":"10.1055\/s-0042-121903"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Palange P, Ward SA, Carlsen K, Casaburi R, Gallagher CG, Gosselink R, et al. Recommendations on the use of exercise testing in clinical practice. European Respiratory Journal. 2007; 29: 185\u2013209.","DOI":"10.1183\/09031936.00046906"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Pedersen BK, Steensberg A, Schjerling P. Exercise and interleukin-6. Current Opinion in Hematology. 2001; 8: 137\u2013141.","DOI":"10.1097\/00062752-200105000-00002"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Dixit S. Can moderate intensity aerobic exercise be an effective and valuable therapy in preventing and controlling the pandemic of COVID-19? Medical Hypotheses. 2020; 143: 109854.","DOI":"10.1016\/j.mehy.2020.109854"},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"Spruit MA, Burtin C, De Boever P, Langer D, Vogiatzis I, Wouters EFM, et al. COPD and exercise: does it make a difference? Breathe. 2016; 12: e38\u2013e49.","DOI":"10.1183\/20734735.003916"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Bernard S, Ribeiro F, Maltais F, Saey D. Prescribing exercise training in pulmonary rehabilitation: a clinical experience. Revista Portuguesa de Pneumologia. 2014; 20: 92\u2013100.","DOI":"10.1016\/j.rppneu.2013.10.005"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Lee AL, Holland AE. Time to adapt exercise training regimens in pulmonary rehabilitation\u2014a review of the literature. International Journal of Chronic Obstructive Pulmonary Disease. 2014; 9: 1275\u20131288.","DOI":"10.2147\/COPD.S54925"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"Garcia S, Rocha M, Pinto P, M F Lopes A, B\u00e1rbara C. Inspiratory muscle training in COPD patients. Revista Portuguesa de Pneumologia. 2008; 14: 177\u2013194.","DOI":"10.1016\/S2173-5115(08)70253-7"},{"key":"ref39","doi-asserted-by":"crossref","unstructured":"Daabis R, Hassan M, Zidan M. Endurance and strength training in pulmonary rehabilitation for COPD patients. Egyptian Journal of Chest Diseases and Tuberculosis. 2017; 66: 231\u2013236.","DOI":"10.1016\/j.ejcdt.2016.07.003"},{"key":"ref40","doi-asserted-by":"crossref","unstructured":"Vogiatzis I. Strategies of muscle training in very severe COPD patients. The European Respiratory Journal. 2011; 38: 971\u2013975.","DOI":"10.1183\/09031936.00075011"},{"key":"ref41","doi-asserted-by":"crossref","unstructured":"Dechman G, Aceron R, Beauchamp M, Bhutani M, Bourbeau J, Brooks D, et al. Delivering pulmonary rehabilitation during the COVID-19 pandemic: a Canadian Thoracic Society position statement. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 2020; 4: 232\u2013235.","DOI":"10.1080\/24745332.2020.1828683"},{"key":"ref42","doi-asserted-by":"publisher","unstructured":"Gautam AP, Arena R, Dixit S, Borghi\u2010Silva A. Pulmonary rehabilitation in COVID-19 pandemic era: The need for a revised approach. 2020. Available at: https:\/\/onlinelibrary.wiley.com\/doi\/ (Accessed: 3 April 2021).","DOI":"10.1111\/resp.13946"},{"key":"ref43","doi-asserted-by":"crossref","unstructured":"Dhont S, Derom E, Van Braeckel E, Depuydt P, Lambrecht BN. The pathophysiology of \u2018happy\u2019 hypoxemia in COVID-19. Respiratory Research. 2020; 21: 198.","DOI":"10.1186\/s12931-020-01462-5"},{"key":"ref44","doi-asserted-by":"crossref","unstructured":"Gosselink R, De Vos J, van den Heuvel SP, Segers J, Decramer M, Kwakkel G. Impact of inspiratory muscle training in patients with COPD: what is the evidence? The European Respiratory Journal. 2011; 37: 416\u2013425.","DOI":"10.1183\/09031936.00031810"},{"key":"ref45","doi-asserted-by":"crossref","unstructured":"Langer D, Ciavaglia C, Faisal A, Webb KA, Neder JA, Gosselink R, et al. Inspiratory muscle training reduces diaphragm activation and dyspnea during exercise in COPD. Journal of Applied Physiology. 2018; 125: 381\u2013392.","DOI":"10.1152\/japplphysiol.01078.2017"},{"key":"ref46","doi-asserted-by":"crossref","unstructured":"Mota S, G\u00fcell R, Barreiro E, Solanes I, Ram\u00edrez-Sarmiento A, Orozco-Levi M, et al. Clinical outcomes of expiratory muscle training in severe COPD patients. Respiratory Medicine. 2007; 101: 516\u2013524.","DOI":"10.1016\/j.rmed.2006.06.024"},{"key":"ref47","doi-asserted-by":"crossref","unstructured":"Komorowski M, Aberegg SK. Using applied lung physiology to understand COVID-19 patterns. British Journal of Anaesthesia. 2020; 125: 250\u2013253.","DOI":"10.1016\/j.bja.2020.05.019"},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"\u00c1lvarez-Herms J, Juli\u00e0-S\u00e1nchez S, Corbi F, Odriozola-Mart\u00ednez A, Burtscher M. Putative role of respiratory muscle training to improve endurance performance in hypoxia: a review. Frontiers in Physiology. 2019; 9: 1970.","DOI":"10.3389\/fphys.2018.01970"},{"key":"ref49","unstructured":"Hristara-Papadopoulou A, Tsanakas J, Diomou G, Papadopoulou O. Current devices of respiratory physiotherapy. Hippokratia. 2008; 12: 211\u2013220."},{"key":"ref50","doi-asserted-by":"crossref","unstructured":"Westerdahl E, Osadnik C, Emtner M. Airway clearance techniques for patients with acute exacerbations of chronic obstructive pulmonary disease: Physical therapy practice in Sweden. Chronic Respiratory Disease. 2019; 16: 147997311985586.","DOI":"10.1177\/1479973119855868"},{"key":"ref51","doi-asserted-by":"crossref","unstructured":"Ernst E. Breathing techniques\u2014adjunctive treatment modalities for asthma? A systematic review. The European Respiratory Journal. 2000; 15: 969\u2013972.","DOI":"10.1183\/09031936.00.15596900"},{"key":"ref52","doi-asserted-by":"crossref","unstructured":"Osadnik CR, McDonald CF, Jones AP, Holland AE. Airway clearance techniques for chronic obstructive pulmonary disease. The Cochrane Database of Systematic Reviews. 2012; CD008328.","DOI":"10.1002\/14651858.CD008328.pub2"},{"key":"ref53","doi-asserted-by":"crossref","unstructured":"Osadnik CR, McDonald CF, Holland AE. Airway clearance techniques in acute exacerbations of COPD: a survey of Australian physiotherapy practice. Physiotherapy. 2013; 99: 101\u2013106.","DOI":"10.1016\/j.physio.2012.01.002"},{"key":"ref54","doi-asserted-by":"crossref","unstructured":"Popkin BM, Du S, Green WD, Beck MA, Algaith T, Herbst CH, et al. Individuals with obesity and COVID\u201019: a global perspective on the epidemiology and biological relationships. Obesity Reviews. 2020; 21: e13128.","DOI":"10.1111\/obr.13128"},{"key":"ref55","doi-asserted-by":"crossref","unstructured":"O\u2019Neill K, O\u2019Donnell AE, Bradley JM. Airway clearance, mucoactive therapies and pulmonary rehabilitation in bronchiectasis. Respirology. 2019; 24: 227\u2013237.","DOI":"10.1111\/resp.13459"},{"key":"ref56","doi-asserted-by":"crossref","unstructured":"Yu S, Guo A, Zhang X. Effects of self-management education on quality of life of patients with chronic obstructive pulmonary disease. International Journal of Nursing Sciences. 2014; 1: 53\u201357.","DOI":"10.1016\/j.ijnss.2014.02.014"},{"key":"ref57","doi-asserted-by":"crossref","unstructured":"Newham JJ, Presseau J, Heslop-Marshall K, Russell S, Ogunbayo OJ, Netts P, et al. Features of self-management interventions for people with COPD associated with improved health-related quality of life and reduced emergency department visits a systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease. 2017; 12: 1705\u20131720.","DOI":"10.2147\/COPD.S133317"},{"key":"ref58","doi-asserted-by":"crossref","unstructured":"Lapp CW, John JF. Managing COVID-19 post viral fatigue syndrome. Fatigue: Biomedicine, Health & Behavior. 2021; 9: 1\u20138.","DOI":"10.1080\/21641846.2021.1890347"},{"key":"ref59","doi-asserted-by":"crossref","unstructured":"Gaber T. Assessment and management of post\u2010COVID fatigue. Progress in Neurology and Psychiatry. 2021; 25: 36\u201339.","DOI":"10.1002\/pnp.698"},{"key":"ref60","doi-asserted-by":"crossref","unstructured":"Barker-Davies RM, O\u2019Sullivan O, Senaratne KPP, Baker P, Cranley M, Dharm-Datta S, et al. The Stanford Hall consensus statement for post-COVID-19 rehabilitation. British Journal of Sports Medicine. 2020; 54: 949\u2013959.","DOI":"10.1136\/bjsports-2020-102596"},{"key":"ref61","doi-asserted-by":"crossref","unstructured":"Greenhalgh T, Knight M, A\u2019Court C, Buxton M, Husain L. Management of post-acute COVID-19 in primary care. British Medical Journal. 2020; 370.","DOI":"10.1136\/bmj.m3026"},{"key":"ref62","doi-asserted-by":"crossref","unstructured":"Tang X, Du R, Wang R, Cao T, Guan L, Yang C, et al. Comparison of hospitalized patients with ARDS caused by COVID-19 and H1N1. Chest. 2020; 158: 195\u2013205.","DOI":"10.1016\/j.chest.2020.03.032"},{"key":"ref63","doi-asserted-by":"crossref","unstructured":"Islam MF, Cotler J, Jason LA. Post-viral fatigue and COVID-19: lessons from past epidemics. Fatigue: Biomedicine, Health & Behavior. 2020; 8: 61\u201369.","DOI":"10.1080\/21641846.2020.1778227"},{"key":"ref64","doi-asserted-by":"crossref","unstructured":"Wing\u00e5rdh A, G\u00f6ransson C, Larsson S, Slinde F, Vanfleteren LGW. Effectiveness of energy conservation techniques in patients with COPD. Respiration. 2020; 99: 409\u2013416.","DOI":"10.1159\/000506816"},{"key":"ref65","doi-asserted-by":"crossref","unstructured":"Velloso M, Jardim JR. Functionality of patients with chronic obstructive pulmonary disease: energy conservation techniques. Jornal Brasileiro de Pneumologia. 2006; 32: 580\u2013586.","DOI":"10.1590\/S1806-37132006000600017"},{"key":"ref66","doi-asserted-by":"crossref","unstructured":"Wagner PD. Ventilation-perfusion matching during exercise. Chest. 1992; 101: 192S\u2013198S.","DOI":"10.1378\/chest.101.5.192S"},{"key":"ref67","doi-asserted-by":"crossref","unstructured":"Rodr\u00edguez-Roisin R, Drakulovic M, Rodr\u00edguez DA, Roca J, Barber\u00e0 JA, Wagner PD. Ventilation-perfusion imbalance and chronic obstructive pulmonary disease staging severity. Journal of Applied Physiology. 2009; 106: 1902\u20131908.","DOI":"10.1152\/japplphysiol.00085.2009"},{"key":"ref68","doi-asserted-by":"crossref","unstructured":"Broadbent E, Garrett J, Jepsen N, Li Ogilvie V, Ahn HS, Robinson H, et al. Using robots at home to support patients with chronic obstructive pulmonary disease: pilot randomized controlled trial. Journal of Medical Internet Research. 2018; 20: e45.","DOI":"10.2196\/jmir.8640"},{"key":"ref69","doi-asserted-by":"crossref","unstructured":"Tay SS, Neo EJ, Tan MM, Tan PL. Post-Critical Care COVID-19 Patient benefits from a robotic patient-guided suspension system for pulmonary rehabilitation. Annals of the Academy of Medicine, Singapore. 2020; 49: 401\u2013404.","DOI":"10.47102\/Annals-acadmedsg.2020165"},{"key":"ref70","unstructured":"States M. Criteria for releasing COVID-19 patients from isolation. World Health Organization. 2020; 1\u20135."},{"key":"ref71","doi-asserted-by":"crossref","unstructured":"Thomas P, Baldwin C, Bissett B, Boden I, Gosselink R, Granger CL, et al. Physiotherapy management for COVID-19 in the acute hospital setting: Recommendations to guide clinical practice. Pneumonia. 2020; 33: 32\u201335.","DOI":"10.1016\/j.jphys.2020.03.011"},{"key":"ref72","unstructured":"PAHO-WHO. Rehabilitation considerations during the outbreak COVID-19. 2020. Available at: www.paho.org\/coronavirus (Accessed: 1 April 2021)."},{"key":"ref73","unstructured":". WHO. Coronavirus disease 2019 (COVID-19) Situation Report \u2013 73. Available at: https:\/\/www.who.int\/docs\/default-source\/coronaviruse\/situation-reports\/20200402-sitrep-73-covid-19.pdf?sfvrsn=5ae25bc7_6 (Accessed: 2 April 2021)."},{"key":"ref74","doi-asserted-by":"crossref","unstructured":"Dimitrov S, Hulteng E, Hong S. Inflammation and exercise: inhibition of monocytic intracellular TNF production by acute exercise via \u03b22-adrenergic activation. Brain, Behavior, and Immunity. 2016; 61: 60\u201368.","DOI":"10.1016\/j.bbi.2016.12.017"},{"key":"ref75","doi-asserted-by":"crossref","unstructured":"Algahtani FD, Hassan SUN, Alsaif B, Zrieq R. Assessment of the quality of life during COVID-19 pandemic: A cross-sectional survey from the kingdom of Saudi Arabia. International Journal of Environmental Research and Public Health. 2021; 18: 1\u201312.","DOI":"10.3390\/ijerph18030847"},{"key":"ref76","doi-asserted-by":"crossref","unstructured":"Paneroni M, Colombo F, Papalia A, Colitta A, Borghi G, Saleri M, et al. Is telerehabilitation a safe and viable option for patients with COPD? A Feasibility Study. Chronic Obstructive Pulmonary Disease. 2015; 12: 217\u2013225.","DOI":"10.3109\/15412555.2014.933794"},{"key":"ref77","doi-asserted-by":"crossref","unstructured":"Cox NS, Mcdonald CF, Hill CJ, O\u2019Halloran P, Alison JA, Zanaboni P, et al. Telerehabilitation for chronic respiratory disease. Cochrane Database of Systematic Reviews. 2018; 2018: CD013040.","DOI":"10.1002\/14651858.CD013040"},{"key":"ref78","doi-asserted-by":"crossref","unstructured":"Salawu A, Green A, Crooks MG, Brixey N, Ross DH, Sivan M. A proposal for multidisciplinary tele-rehabilitation in the assessment and rehabilitation of COVID-19 survivors. International Journal of Environmental Research and Public Health. 2020; 17: 1\u201313.","DOI":"10.3390\/ijerph17134890"},{"key":"ref79","doi-asserted-by":"crossref","unstructured":"Rutkowski S. Management challenges in chronic obstructive pulmonary disease in the COVID-19 pandemic\u202f: telehealth and virtual reality. 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