{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T18:07:24Z","timestamp":1760551644950,"version":"3.41.2"},"reference-count":105,"publisher":"IMR Press","issue":"2","license":[{"start":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T00:00:00Z","timestamp":1645401600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Cardiovasc. Med."],"abstract":"<jats:p>Patients with acute myocardial infarction (MI) complicated by cardiogenic shock (CS) have poor prognosis. Over the last two decades, there has been some improvement in mortality rates associated with CS. Initial measures to stabilise patients should follow a shock protocol, including therapies such as volume expansion, inotropes\/vasopressors, and early coronary revascularisation. The use of mechanical circulatory support (MCS) devices demonstrated better haemodynamic and metabolic profiles for patients with CS. However, these benefits have not been consistently translated into significant reductions in cardiovascular adverse events. This review aims to discuss emerging concepts related to CS including an update on its classification and pathophysiology. The focus is on recent evidence regarding the use of MCS and the timing of initiating in patients with CS.<\/jats:p>","DOI":"10.31083\/j.rcm2302071","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T01:40:01Z","timestamp":1645753201000},"source":"Crossref","is-referenced-by-count":11,"title":["Mechanical circulatory support in acute myocardial infarction complicated by cardiogenic shock"],"prefix":"10.31083","volume":"23","author":[{"given":"Ayman","family":"Al-atta","sequence":"first","affiliation":[{"name":"Department of Cardiology, Freeman Hospital, NE7 7DN Newcastle upon Tyne, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Zaidan","sequence":"first","affiliation":[{"name":"Cardiology Department,Henry Ford Hospital, Detroit, MI 48202, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Abdalwahab","sequence":"first","affiliation":[{"name":"Department of Cardiology, Freeman Hospital, NE7 7DN Newcastle upon Tyne, UK"},{"name":"Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, 31527 Gharbia Governorate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amjad Ghazal","family":"Asswad","sequence":"first","affiliation":[{"name":"Department of Cardiology, Freeman Hospital, NE7 7DN Newcastle upon Tyne, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohaned","family":"Egred","sequence":"first","affiliation":[{"name":"Department of Cardiology, Freeman Hospital, NE7 7DN Newcastle upon Tyne, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azfar","family":"Zaman","sequence":"first","affiliation":[{"name":"Department of Cardiology, Freeman Hospital, NE7 7DN Newcastle upon Tyne, UK"},{"name":"Translational and Clinical Research Institute, Newcastle University, NE1 7RU Newcastle, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Alkhalil","sequence":"first","affiliation":[{"name":"Department of Cardiology, Freeman Hospital, NE7 7DN Newcastle upon Tyne, UK"},{"name":"Translational and Clinical Research Institute, Newcastle University, NE1 7RU Newcastle, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2022,2,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"van Diepen S, Katz JN, Albert NM, Henry TD, Jacobs AK, Kapur NK, et al. 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