{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T08:11:12Z","timestamp":1794039072376,"version":"4.8.0"},"reference-count":19,"publisher":"IMR Press","issue":"7","license":[{"start":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T00:00:00Z","timestamp":1656028800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Cardiovasc. Med."],"abstract":"<jats:p>Objective: Acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) remains associated with a high rate of mortality and disabling morbidity. Coronary artery bypass grafting (CABG) is seldom considered in this setting due to the fear of peri-operative complications. Here, we analysed the outcome of CS patients undergoing CABG within 48 hours after diagnosed with AMI. Methods: A single-center, retrospective data analysis was performed in 220 AMI patients with CS that underwent CABG within 48 hours between 01\/2001 and 01\/2018. Results: 141 patients were diagnosed with ST-elevation myocardial infarction (STEMI), 79 with non-STEMI (NSTEMI). Median age was 67 (60; 72) for STEMI, and 68 (60.8; 75.0) years for NSTEMI patients (p = 0.190). 52.5% of STEMI patients and 39.2% of NSTEMI patients had suffered from cardiac arrest (CA) pre-operatively (p = 0.049). Coronary 3-vessel disease was present in most patients (78.0% STEMI vs 83.5% NSTEMI; p = 0.381). Percutaneous coronary interventions (PCI) were performed in 32.6% STEMI and 27.8% NSTEMI patients (p = 0.543) prior to surgery. Time from diagnosis to surgery was shorter in STEMI patients (3.92 (2.67; 5.98) vs 7.50 (4.78; 16.74) hours; p &lt; 0.001). A complete revascularization was achieved in 82.3% of STEMI and 73.4% of NSTEMI cases (p = 0.116). Post-operative low cardiac output occurred in 14.2% of STEMI vs 8.9% of NSTEMI patients (p = 0.289). The rate of cerebrovascular injury\u2013including hypoxic brain damage was 12.1% for STEMI and 10.1% among NSTEMI patients. (p = 0.825). 30-day mortality was 32.6% after STEMI vs 31.6% in NSTEMI cases (p = 0.285). Conclusions: In contrast to the discouraging data concerning the role of PCI in AMI patients with CS and complex coronary artery disease, CABG may represent a treatment option worth considering.<\/jats:p>","DOI":"10.31083\/j.rcm2307237","type":"journal-article","created":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T09:09:30Z","timestamp":1656061770000},"source":"Crossref","is-referenced-by-count":8,"title":["Coronary Artery Bypass Grafting in Patients with Acute Myocardial Infarction and Cardiogenic Shock"],"prefix":"10.31083","volume":"23","author":[{"given":"Christina","family":"Grothusen","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"},{"name":"Medizinische Klinik I, St. Johannes Hospital Dortmund, 44137 Dortmund, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Friedrich","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulysses","family":"Ulbricht","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jette","family":"Meinert","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Attmann","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Huenges","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Borzikowsky","sequence":"first","affiliation":[{"name":"Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assad","family":"Haneya","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Schoettler","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Cremer","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2022,6,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Thiele H, Akin I, Sandri M, Fuernau G, de Waha S, Meyer-Saraei R, et al. PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock. New England Journal of Medicine. 2017; 377: 2419\u20132432.","DOI":"10.1056\/NEJMoa1710261"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"O\u2019Neill WW, Schreiber T, Wohns DH, Rihal C, Naidu SS, Civitello AB, et al. The Current Use of Impella 2.5 in Acute Myocardial Infarction Complicated by Cardiogenic Shock: Results from the USpella Registry. Journal of Interventional Cardiology. 2014; 27: 1\u201311.","DOI":"10.1111\/joic.12080"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Lawler PR, Silver DA, Scirica BM, Couper GS, Weinhouse GL, Camp PC. Extracorporeal Membrane Oxygenation in Adults with Cardiogenic Shock. Circulation. 2015; 131: 676\u2013680.","DOI":"10.1161\/CIRCULATIONAHA.114.006647"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Collet JP, Thiele H, Barbato E, Bauersachs J, Dendale P, Edvardsen T, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal. 2021; 42: 1289\u20131367.","DOI":"10.1093\/eurheartj\/ehaa909"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. European Heart Journal. 2017; 70: 1082.","DOI":"10.1016\/j.rec.2017.11.010"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Neumann F-J, Sousa-Uva M, Ahlsson A, Alfonso F, Banning AP, Benedetto U, et al. 2018 ESC\/EACTS Guidelines on myocardial revascularization. European Heart Journal. 2019; 40: 87\u2013165.","DOI":"10.1093\/eurheartj\/ehy855"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Hochman JS, Sleeper LA, Webb JG, Sanborn TA, White HD, Talley JD, et al. Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock. New England Journal of Medicine. 1999; 341: 625\u2013634.","DOI":"10.1056\/NEJM199908263410901"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Davierwala PM, Leontyev S, Verevkin A, Rastan AJ, Mohr M, Bakhtiary F, et al. Temporal Trends in Predictors of Early and Late Mortality after Emergency Coronary Artery Bypass Grafting for Cardiogenic Shock Complicating Acute Myocardial Infarction. Circulation. 2016; 134: 1224\u20131237.","DOI":"10.1161\/CIRCULATIONAHA.115.021092"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Acharya D, Gulack BC, Loyaga-Rendon RY, Davies JE, He X, Brennan JM, et al. Clinical Characteristics and Outcomes of Patients with Myocardial Infarction and Cardiogenic Shock Undergoing Coronary Artery Bypass Surgery: Data from the Society of Thoracic Surgeons National Database. The Annals of Thoracic Surgery. 2016; 101: 558\u2013566.","DOI":"10.1016\/j.athoracsur.2015.10.051"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Grothusen C, Friedrich C, Loehr J, Meinert J, Ohnewald E, Ulbricht U, et al. Outcome of Stable Patients with Acute Myocardial Infarction and Coronary Artery Bypass Surgery within 48 Hours: a Single\u2010Center, Retrospective Experience. Journal of the American Heart Association. 2017; 6: e005498.","DOI":"10.1161\/JAHA.117.005498"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"White HD, Assmann SF, Sanborn TA, Jacobs AK, Webb JG, Sleeper LA, et al. Comparison of Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting after Acute Myocardial Infarction Complicated by Cardiogenic Shock. Circulation. 2005; 112: 1992\u20132001.","DOI":"10.1161\/CIRCULATIONAHA.105.540948"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Hawranek M, Gierlotka M, Pres D, Zembala M, G\u0105sior M. Nonroutine Use of Intra-Aortic Balloon Pump in Cardiogenic Shock Complicating Myocardial Infarction with Successful and Unsuccessful Primary Percutaneous Coronary Intervention. JACC: Cardiovascular Interventions. 2018; 11: 1885\u20131893.","DOI":"10.1016\/j.jcin.2018.07.030"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Zheng F, Sheinberg R, Yee M, Ono M, Zheng Y, Hogue CW. Cerebral near-Infrared Spectroscopy Monitoring and Neurologic Outcomes in Adult Cardiac Surgery Patients. Anesthesia & Analgesia. 2013; 116: 663\u2013676.","DOI":"10.1213\/ANE.0b013e318277a255"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Mariscalco G, Biancari F, Juvonen T, Zanobini M, Cottini M, Banach M, et al. Red blood cell transfusion is a determinant of neurological complications after cardiac surgery. Interactive Cardiovascular and Thoracic Surgery. 2015; 20: 166\u2013171.","DOI":"10.1093\/icvts\/ivu360"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Mehaffey JH, Schubert SA, Gelvin MG, Charles EJ, Hawkins RB, Johnston LE, et al. A New Intraoperative Protocol for Reducing Perioperative Transfusions in Cardiac Surgery. The Annals of Thoracic Surgery. 2017; 104: 176\u2013181.","DOI":"10.1016\/j.athoracsur.2016.10.032"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Whiting D, DiNardo JA. TEG and ROTEM: Technology and clinical applications. American Journal of Hematology. 2014; 89: 228\u2013232.","DOI":"10.1002\/ajh.23599"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Gasche Y, Hassager C, et al. Targeted temperature management at 33 degrees C versus 36 degrees C after cardiac arrest. The New England Journal of Medicine. 2013; 369: 2197\u20132206.","DOI":"10.1056\/NEJMoa1310519"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Callaway CW, Schmicker RH, Brown SP, Albrich JM, Andrusiek DL, Aufderheide TP, et al. Early coronary angiography and induced hypothermia are associated with survival and functional recovery after out-of-hospital cardiac arrest. Resuscitation. 2014; 85: 657\u2013663.","DOI":"10.1016\/j.resuscitation.2013.12.028"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, et al. Treatment of Comatose Survivors of out-of-Hospital Cardiac Arrest with Induced Hypothermia. The New England Journal of Medicine. 2002; 346: 557\u2013563.","DOI":"10.1056\/NEJMoa003289"}],"container-title":["Reviews in Cardiovascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.imrpress.com\/journal\/RCM\/23\/7\/10.31083\/j.rcm2307237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T17:57:56Z","timestamp":1732730276000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/RCM\/23\/7\/10.31083\/j.rcm2307237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,24]]},"references-count":19,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022]]}},"alternative-id":["S1530-6550(22)00606-8"],"URL":"https:\/\/doi.org\/10.31083\/j.rcm2307237","relation":{},"ISSN":["1530-6550","2153-8174"],"issn-type":[{"value":"1530-6550","type":"print"},{"value":"2153-8174","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,24]]},"article-number":"237"}}