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Cardiovasc. Med."],"abstract":"<jats:p>Background: To determine the impacts of aortic occlusion duration \u226590 minutes on short- and long-term survival in patients with infectious endocarditis (IE). Methods: We retrospectively reviewed patients who underwent surgical treatment for IE at our hospital. Results: In the present study, 368 patients had an aortic occlusion duration \u226590 minutes (45.2%). Aortic occlusion length \u226590 minutes was associated with in-hospital mortality. A duration from symptom onset to operation \u22651 month, vegetation diameter \u226510 mm, cardiopulmonary bypass (CPB) time \u2265180 minutes, preoperative left ventricular end-diastolic diameter (LVEDD) \u226552 mm, preoperative aortic regurgitation \u22654 cm2, and preoperative mitral regurgitation (MR) \u22658 cm2 were associated with an aortic occlusion duration \u226590 minutes. Aortic occlusion duration \u226590 minutes was also significantly associated with 1- and 5-year mortality after cardiac operation and was also a significant risk factor for long-term survival. Cox proportional hazards regression for all-cause mortality identified symptom-to-operation interval \u22651 month, vegetation size \u226510 mm, aortic occlusion duration \u226590 minutes, and red blood cell transfusion volume \u22652 units as associated with all-cause mortality. There was a significant positive correlation between CPB duration and aortic occlusion duration. A CPB duration &gt;120.5 minutes had 74.5% sensitivity and 61.9% specificity for diagnosing an aortic occlusion duration \u226590 minutes. Conclusions: In our investigation, an aortic occlusion duration \u226590 minutes in patients with infectious endocarditis was a significant risk factor for both short- and long-term mortality.<\/jats:p>","DOI":"10.31083\/rcm47654","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T10:31:43Z","timestamp":1785407503000},"source":"Crossref","is-referenced-by-count":0,"title":["Impacts of Aortic Occlusion Duration \u226590 Minutes on Short- and Long-Term Outcomes in Infectious Endocarditis"],"prefix":"10.31083","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6876-1701","authenticated-orcid":true,"given":"Jing-bin","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, The People\u2019s Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, 530000 Nanning, Guangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine, 530000 Nanning, Guangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-chao","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, The People\u2019s Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, 530000 Nanning, Guangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao-ke","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, The People\u2019s Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, 530000 Nanning, Guangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Pettersson GB, Hussain ST. 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