{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:58:26Z","timestamp":1790697506753,"version":"4.1.0"},"reference-count":31,"publisher":"IMR Press","issue":"9","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Cardiovasc. Med."],"abstract":"<jats:p>Geriatric femoral neck fractures are associated with high mortality. Early surgery within 48 hours improves survival, whereas delayed arthroplasty is associated with a 41% increase in mortality. Multimorbidity in this population often prolongs preoperative optimization, thereby exacerbating perioperative risk. Current evidence indicates that 5%\u201310% of patients with hip fractures have concomitant severe aortic stenosis (AS), which independently increases the risk of anesthesia-related complications. Perioperative acute myocardial infarction further increases mortality risk, making cardiac management a critical challenge. The advent of transcatheter aortic valve replacement (TAVR) has revolutionized care paradigms. Nonetheless, this situation requires multidisciplinary consensus on optimizing the fracture-to-surgery interval, antithrombotic bridging strategies, and concomitant coronary revascularization. Here, we present a case of single-stage aorta-coronary computed tomography angiography (CTA), percutaneous coronary intervention (PCI), and TAVR in an octogenarian with femoral neck fracture, severe AS, and non-ST-elevation myocardial infarction (NSTEMI). This pioneering case is accompanied by a systematic review of contemporary management strategies.<\/jats:p>","DOI":"10.31083\/rcm50145","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:57:11Z","timestamp":1790693831000},"source":"Crossref","is-referenced-by-count":0,"title":["Single-Stage Computed Tomography Angiography, Percutaneous Coronary Intervention, and Transcatheter Aortic Valve Replacement in an Octogenarian With Femoral Neck Fracture, Non-ST-Elevation Myocardial Infarction, and Severe Aortic Stenosis: A Case Report and Literature Review of Multidisciplinary Approaches"],"prefix":"10.31083","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2871-5115","authenticated-orcid":true,"given":"Ming","family":"Zhang","sequence":"first","affiliation":[{"name":"Senior Department of Cardiology, The First Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7471-890X","authenticated-orcid":true,"given":"Xietian","family":"Pan","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Yang","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The First Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1375-4760","authenticated-orcid":true,"given":"Yang","family":"Mu","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Jiang","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Chen","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0915-5681","authenticated-orcid":true,"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2610-695X","authenticated-orcid":true,"given":"Lin","family":"Wang","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8052-9099","authenticated-orcid":true,"given":"Jiayue","family":"Li","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0007-845X","authenticated-orcid":true,"given":"Jing","family":"Liu","sequence":"additional","affiliation":[{"name":"Senior Department of Anesthesiology, The First Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2503-4445","authenticated-orcid":true,"given":"Zhuo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Senior Department of Orthopedics, The First Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1054-1198","authenticated-orcid":true,"given":"Changfu","family":"Liu","sequence":"additional","affiliation":[{"name":"Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, 100853 Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Brauer CA, Coca-Perraillon M, Cutler DM, Rosen AB. 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Shamrock Lumbar Plexus Block for Hip Hemiarthroplasty in a High Risk Elderly Patient with Hip Fracture. Journal of Long-Term Effects of Medical Implants. 2022; 32: 73\u201376.","DOI":"10.1615\/JLongTermEffMedImplants.2021039397"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"\u00c7a\u011f\u0131ran Z, Vahabi A, \u00d6zg\u00fcl KK, Aljasim O, Karaman S, \u00d6zkay\u0131n N, et al. Unilateral Spinal Anesthesia in Hip Fracture Surgery for Geriatric Patients With High Cardiovascular Risk due to Aortic Stenosis is Safe and Effective. Geriatric Orthopaedic Surgery & Rehabilitation. 2024; 15: 21514593241280908.","DOI":"10.1177\/21514593241280908"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Mitsuta Y, Okamura Y, Miyamoto Y, Tanahira D. Simultaneous transcatheter aortic valve implantation and femoral osteosynthesis: a case report. 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Clinical Chemistry and Laboratory Medicine. 2013; 51: 713\u2013727.","DOI":"10.1515\/cclm-2012-0849"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"R\u0103dulescu M, Necula BR, Mironescu SA, Roman MD, Schuh A, Necula RD. Is the Timing of Surgery a Sufficient Predictive Factor for Outcomes in Patients with Proximal Femur Fractures? A Systematic Review. Journal of Personalized Medicine. 2024; 14: 773.","DOI":"10.3390\/jpm14070773"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"Terr\u00e9 JA, Torrado J, George I, Harari R, Cox-Alomar PR, Villablanca PA, et al. Aortic Stenosis Management in Patients With Acute Hip Fracture. JACC. Advances. 2024; 3: 100912.","DOI":"10.1016\/j.jacadv.2024.100912"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"Sennerby U, Melhus H, Gedeborg R, Byberg L, Garmo H, Ahlbom A, et al. Cardiovascular diseases and risk of hip fracture. 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Perioperative risk of major non-cardiac surgery in patients with severe aortic stenosis: a reappraisal in contemporary practice. European Heart Journal. 2014; 35: 2372\u20132381.","DOI":"10.1093\/eurheartj\/ehu044"},{"key":"ref28","doi-asserted-by":"publisher","unstructured":"Sorrentino R, Santoro C, Bardi L, Rigolin V, Gentile F. Non-cardiac surgery in patients with valvular heart disease. Heart. 2022; 108: 1171\u20131178.","DOI":"10.1136\/heartjnl-2021-319160"},{"key":"ref29","doi-asserted-by":"publisher","unstructured":"Ahmed T, Safdar A. The Management Dilemma: Concomitant Acute Hip Fracture and Severe Asymptomatic Aortic Stenosis. Cureus. 2020; 12: e7527.","DOI":"10.7759\/cureus.7527"},{"key":"ref30","doi-asserted-by":"publisher","unstructured":"Collet JP, Thiele H, Barbato E, Barth\u00e9l\u00e9my O, Bauersachs J, Bhatt DL, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal. 2021; 42: 1289\u20131367.","DOI":"10.1093\/eurheartj\/ehaa575"},{"key":"ref31","doi-asserted-by":"publisher","unstructured":"Writing Committee Members, Lawton JS, Tamis-Holland JE, Bangalore S, Bates ER, et al. 2021 ACC\/AHA\/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines. Journal of the American College of Cardiology. 2022; 79: e21\u2013e129.","DOI":"10.1016\/j.jacc.2021.09.006"}],"container-title":["Reviews in Cardiovascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.imrpress.com\/journal\/RCM\/27\/9\/10.31083\/RCM50145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:57:43Z","timestamp":1790693863000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/RCM\/27\/9\/10.31083\/RCM50145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,17]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026]]}},"alternative-id":["S2153-8174(26)04655-0"],"URL":"https:\/\/doi.org\/10.31083\/rcm50145","relation":{},"ISSN":["1530-6550","2153-8174"],"issn-type":[{"value":"1530-6550","type":"print"},{"value":"2153-8174","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,17]]},"article-number":"50145"}}