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Cardiovasc. Med."],"abstract":"<jats:p>Fibroblast activation protein inhibitor (FAPI) positron emission tomography\/computed tomography (PET\/CT) has emerged as a promising molecular imaging modality for visualizing fibroblast activation and extracellular matrix remodeling. In addition to its established role in oncology imaging, FAPI PET\/CT is gaining recognition in the evaluation of cardiovascular disease. Emerging evidence suggests that this technique may provide molecular insights into atrial fibroblast activation and the development of a fibrotic substrate in atrial fibrillation. Meanwhile, related findings from other arrhythmias further support a potential link between myocardial fibroblast activation and electrophysiological remodeling. This review summarizes the current evidence on FAPI PET\/CT imaging in atrial fibrillation, discusses related findings in other cardiovascular conditions, and highlights future directions for research in arrhythmia imaging.<\/jats:p>","DOI":"10.31083\/rcm50485","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:57:11Z","timestamp":1790693831000},"source":"Crossref","is-referenced-by-count":0,"title":["Fibroblast Activation Protein Inhibitor Positron Emission Tomography Imaging in Atrial Fibrillation: Current Evidence and Future Perspectives"],"prefix":"10.31083","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4449-5589","authenticated-orcid":true,"given":"Yi","family":"Xu","sequence":"first","affiliation":[{"name":"School of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China"},{"name":"Department of Cardiology, The First Affiliated Hospital of Jinan University, 510632 Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiyi","family":"Qiu","sequence":"additional","affiliation":[{"name":"School of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuxian","family":"Guo","sequence":"additional","affiliation":[{"name":"School of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianyun","family":"Wang","sequence":"additional","affiliation":[{"name":"Health Management Division, Shunde Hospital, Southern Medical University (The First People\u2019s Hospital of Shunde), 528308 Foshan, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjin","family":"Tang","sequence":"additional","affiliation":[{"name":"School of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China"},{"name":"Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, 510632 Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chongyi","family":"Huang","sequence":"additional","affiliation":[{"name":"School of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China"},{"name":"Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, 510632 Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9865-2196","authenticated-orcid":true,"given":"Jun","family":"Guo","sequence":"additional","affiliation":[{"name":"School of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China"},{"name":"Department of Cardiology, The First Affiliated Hospital of Jinan University, 510632 Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Wang","sequence":"additional","affiliation":[{"name":"School of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China"},{"name":"Department of Cardiology, The First Affiliated Hospital of Jinan University, 510632 Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2026,9,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Karur GR, Aneja A, Stojanovska J, Hanneman K, Latchamsetty R, Kersting D, et al. 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