{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T22:27:26Z","timestamp":1788647246091,"version":"build-2803163510"},"reference-count":39,"publisher":"IMR Press","issue":"11","license":[{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Neurol."],"abstract":"<jats:p>Objective: This study aimed to systematically review the available evidence on the effects of boxing interventions on people with Parkinson disease. Methods: Four electronic databases were searched systematically from their inception until December 2023. The methodological quality of the included studies was assessed using the Physiotherapy Evidence Database and Methodological Index for Non-Randomized Studies scales. Results: A total of 13 studies were included. Data synthesis indicated that participants who performed boxing programs did not have a significant effect in the polled data on functional mobility, balance, motor symptoms, gait and cardiorespiratory fitness Accordingly, for the effects of boxing on self-reported quality of life, the polled data showed a non-significant trend towards improving Hedges' g. Also, when the analysis was performed by comparing the experimental and control groups, the results remained non-significant. Conclusions: The evidence regarding the use of boxing as a program exercise for patients with Parkinson disease remains uncertain. Preliminary findings indicate that participation in boxing does not demonstrate a substantial impact on either physical or mental health outcomes.<\/jats:p>","DOI":"10.31083\/rn36478","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T02:27:43Z","timestamp":1737426463000},"source":"Crossref","is-referenced-by-count":3,"title":["The Efficacy of Boxing Training on Patients with Parkinson's Disease: Systematic Review and Meta-Analysis"],"prefix":"10.31083","volume":"79","author":[{"given":"Daniel","family":"Gonz\u00e1lez-Devesa","sequence":"first","affiliation":[{"name":"Well-Move Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36310 Vigo, Spain"},{"name":"Grupo de Investigaci\u00f3n en Actividad F\u00edsica, Educaci\u00f3n, y Salud (GIAFES), Universidad Cat\u00f3lica de \u00c1vila, C\/ Canteros, 05005, \u00c1vila, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Ay\u00e1n","sequence":"first","affiliation":[{"name":"Well-Move Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36310 Vigo, Spain"},{"name":"Departamento de Did\u00e1cticas Especiais, Universidad de Vigo, 36310 Vigo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel Adriano","family":"Sanchez-Lastra","sequence":"first","affiliation":[{"name":"Well-Move Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36310 Vigo, Spain"},{"name":"Departamento de Did\u00e1cticas Especiais, Universidad de Vigo, 36310 Vigo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciro","family":"Guti\u00e9rrez-Hong","sequence":"first","affiliation":[{"name":"Research Group in Tecnologia Aplicada a l\u2019Alt Rendiment i la Salut (TAARS), TecnoCampus, Department of Health Sciences, Pompeu Fabra University, 08302 Matar\u00f3, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8988-0814","authenticated-orcid":true,"given":"Adri\u00e1n","family":"Garc\u00eda-Fresneda","sequence":"first","affiliation":[{"name":"Research Group in Tecnologia Aplicada a l\u2019Alt Rendiment i la Salut (TAARS), TecnoCampus, Department of Health Sciences, Pompeu Fabra University, 08302 Matar\u00f3, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Carlos","family":"Diz","sequence":"first","affiliation":[{"name":"Well-Move Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36310 Vigo, Spain"},{"name":"Departamento de Did\u00e1cticas Especiais, Universidad de Vigo, 36310 Vigo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2024,12,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Goldman JG, Volpe D, Ellis TD, Hirsch MA, Johnson J, Wood J, et al. 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Systematic review and meta-analysis of randomised controlled trials on the effects of yoga in people with Parkinson\u2019s disease. Disability and Rehabilitation. 2022; 44: 6210\u20136229.","DOI":"10.1080\/09638288.2021.1966522."},{"key":"ref31","doi-asserted-by":"publisher","unstructured":"Benka Wall\u00e9n M, Franz\u00e9n E, Nero H, Hagstr\u00f6mer M. Levels and Patterns of Physical Activity and Sedentary Behavior in Elderly People With Mild to Moderate Parkinson Disease. Physical Therapy. 2015; 95: 1135\u20131141.","DOI":"10.2522\/ptj.20140374."},{"key":"ref32","doi-asserted-by":"publisher","unstructured":"Bou\u00e7a-Machado R, Maetzler W, Ferreira JJ. What is Functional Mobility Applied to Parkinson\u2019s Disease? Journal of Parkinson\u2019s Disease. 2018; 8: 121\u2013130.","DOI":"10.3233\/JPD-171233."},{"key":"ref33","doi-asserted-by":"publisher","unstructured":"Shen X, Wong-Yu ISK, Mak MKY. Effects of Exercise on Falls, Balance, and Gait Ability in Parkinson\u2019s Disease: A Meta-analysis. Neurorehabilitation and Neural Repair. 2016; 30: 512\u2013527.","DOI":"10.1177\/1545968315613447."},{"key":"ref34","doi-asserted-by":"publisher","unstructured":"van der Kolk NM, King LA. Effects of exercise on mobility in people with Parkinson\u2019s disease. Movement Disorders: Official Journal of the Movement Disorder Society. 2013; 28: 1587\u20131596.","DOI":"10.1002\/mds.25658."},{"key":"ref35","doi-asserted-by":"publisher","unstructured":"Amano S, Nocera JR, Vallabhajosula S, Juncos JL, Gregor RJ, Waddell DE, et al. The effect of Tai Chi exercise on gait initiation and gait performance in persons with Parkinson\u2019s disease. Parkinsonism & Related Disorders. 2013; 19: 955\u2013960.","DOI":"10.1016\/j.parkreldis.2013.06.007."},{"key":"ref36","doi-asserted-by":"publisher","unstructured":"Mirelman A, Bonato P, Camicioli R, Ellis TD, Giladi N, Hamilton JL, et al. Gait impairments in Parkinson\u2019s disease. The Lancet. Neurology. 2019; 18: 697\u2013708.","DOI":"10.1016\/S1474-4422(19)30044-4."},{"key":"ref37","doi-asserted-by":"publisher","unstructured":"Xia R, Mao ZH. Progression of motor symptoms in Parkinson\u2019s disease. Neuroscience Bulletin. 2012; 28: 39\u201348.","DOI":"10.1007\/s12264-012-1050-z."},{"key":"ref38","doi-asserted-by":"publisher","unstructured":"Panassollo TRB, Mawston G, Taylor D, Lord S. Targeting exercise intensity and aerobic training to improve outcomes in Parkinson\u2019s disease. Sport Sciences for Health. 2024; 20: 287\u2013297.","DOI":"10.1007\/s11332-024-01165-0."},{"key":"ref39","doi-asserted-by":"publisher","unstructured":"Dauwan M, Begemann MJH, Slot MIE, Lee EHM, Scheltens P, Sommer IEC. Physical exercise improves quality of life, depressive symptoms, and cognition across chronic brain disorders: a transdiagnostic systematic review and meta-analysis of randomized controlled trials. 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