{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:10:18Z","timestamp":1782252618622,"version":"3.54.5"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":425,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dysgerminomas comprise approximately 2\u20135% of all ovarian malignancies and mostly affect young adolescent women. Primary comprehensive surgery and adjuvant chemotherapy consisting of bleomycin, etoposide, and cisplatin (BEP) are the current recommended treatment options, the latter reserved for advanced stages (FIGO II\u2013IV).<\/jats:p><jats:p>We report two patients aged 20 and 26 years who presented with an initial FIGO stage IA, but inadequately assessed. Both were subsequently diagnosed with recurrent malignant dysgerminoma and para\u2010aortic lymph node metastasis. Neither had received comprehensive staging at initial surgery nor adjuvant radio or chemotherapy. Both needed extensive surgery and multiagent chemotherapy for survival and belong to the small percentage of FIGO IA dysgerminoma patients showing a relapse. Comprehensive initial surgery including systematic para\u2010aortic lymphadenectomy and adjuvant chemotherapy at tertiary referral centers is needed to minimize the treatment burden.<\/jats:p>","DOI":"10.3109\/00016340903242461","type":"journal-article","created":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T14:35:49Z","timestamp":1259678149000},"page":"1288-1290","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Para\u2010aortic lymph node metastasis in malignant dysgerminoma of the ovary"],"prefix":"10.1111","volume":"88","author":[{"given":"BENJAMIN","family":"KASENDA","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PHILIPP","family":"HARTER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TOBIAS","family":"HIRSCH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ALEXANDER","family":"AST","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHRISTINE","family":"BUHRMANN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FLORIAN","family":"GLASER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANDREAS","family":"DU BOIS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1995.1240"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2006.00911.x"},{"key":"e_1_2_5_4_2","first-page":"881","article-title":"Transformation of ovarian dysgerminoma to yolk sac tumor: evidence for a histogenetic continuum","volume":"8","author":"Parkash V","year":"1995","journal-title":"Mod Pathol"},{"key":"e_1_2_5_5_2","volume-title":"Interdisziplin\u00e4re S2k\u2010Leitlinie f\u00fcr die Diagnostik und Therapie maligner Ovarialtumoren [Interdisciplinary S2k\u2010guidelines for diagnostics and therapy for malignant tumors of the ovary]","author":"Komission OVAR, AGOe.V","year":"2007"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910215)67:4<1084::AID-CNCR2820670436>3.0.CO;2-E"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(96)00021-X"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.00931.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2004.07.044"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1990.8.4.715"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19861215)58:12<2594::AID-CNCR2820581207>3.0.CO;2-Z"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-5-71"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.05.029"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016340903242461","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016340903242461","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T22:50:28Z","timestamp":1697064628000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016340903242461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.3109\/00016340903242461"],"URL":"https:\/\/doi.org\/10.3109\/00016340903242461","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11]]},"assertion":[{"value":"2010-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}