{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T12:18:36Z","timestamp":1700828316015},"reference-count":22,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":425,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective.<\/jats:italic> To investigate pregnancy complications and offspring sex ratio according to mode of conception in women with polycystic ovary syndrome (PCOS). <jats:italic>Design.<\/jats:italic> Retrospective, descriptive study. <jats:italic>Setting.<\/jats:italic> Tertiary, university hospital. <jats:italic>Population.<\/jats:italic> A total of 176 women with PCOS diagnosed according to the Rotterdam criteria. <jats:italic>Methods.<\/jats:italic> Women with PCOS who have participated in one or more clinical studies were invited to answer a questionnaire on the mode of conception, pregnancy complications, gestational length and offspring gender. A total of 139 women responded. Data were quality checked against hospital files. <jats:italic>Main outcome measures.<\/jats:italic> Fertility, mode of conception, offspring gender and pregnancy complications. <jats:italic>Results.<\/jats:italic> More than half (54%) of the singleton pregnancies were conceived spontaneously. More complications were seen in pregnancies achieved while using metformin than without (<jats:italic>p<\/jats:italic> = 0.02). Compared to spontaneous conception, more boys than girls were born in singleton pregnancies after in vitro fertilization\/intracytoplasmatic sperm injection treatment (<jats:italic>p<\/jats:italic> = 0.004). <jats:italic>Conclusions.<\/jats:italic> In women with PCOS the mode of conception may influence both the rate of pregnancy complications and the offspring sex ratio.<\/jats:p>","DOI":"10.3109\/00016340903294280","type":"journal-article","created":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T14:35:49Z","timestamp":1259678149000},"page":"1261-1266","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Sex ratio and pregnancy complications according to mode of conception in women with polycystic ovary syndrome"],"prefix":"10.1111","volume":"88","author":[{"given":"ESZTER","family":"VANKY","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BJ\u00d8RN","family":"BACKE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SVEN M.","family":"CARLSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199509283331307"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.297.6655.1024"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030975"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dml036"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh103"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.06.022"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh347"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh248"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh098"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1989.tb03288.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh263"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.10.2573"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.09.047"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2004.11.044"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dei009"},{"key":"e_1_2_6_18_2","unstructured":"Medisinsk f\u00f8dselsregister.Perinatal mortality 2003.http:\/\/www.fhi.no"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61041-7"},{"key":"e_1_2_6_20_2","first-page":"873","article-title":"The human sex ratio. 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