{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T13:52:49Z","timestamp":1764078769578},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":364,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective.<\/jats:italic> To find out if body mass index (BMI) was associated with clinico\u2010pathological features and prognosis in epithelial ovarian cancer (EOC). <jats:italic>Design.<\/jats:italic> Retrospective cohort study. <jats:italic>Setting.<\/jats:italic> Patients with EOC, who underwent primary surgery and postoperative chemotherapy in the \u00d6rebro Medical Region, Sweden, 1994\u20132003. <jats:italic>Sample.<\/jats:italic> A total of 446 patients with stage I\u2013IV EOC, who underwent primary surgery and chemotherapy with information of values of height and weight at the start of chemotherapy were eligible. <jats:italic>Methods.<\/jats:italic> Patients were stratified by BMI according to guidelines set forth by the World Health Organization. Pearson's chi\u2010squared test was used for univariate analyses. The level of statistical significance was <jats:italic>p<\/jats:italic> &lt; 0.05. <jats:italic>Main outcome measures.<\/jats:italic> The survival curves were generated by using the Kaplan\u2010Meier method, and in multivariate analyses the Cox regression model was used with cancer\u2010specific survival as the end point. <jats:italic>Results.<\/jats:italic> Of the patients, 5% were underweight (BMI &lt; 18.5), 55% were of ideal body weight (BMI 18.5\u201325), 25% were overweight (BMI 25\u201330) and 15% were obese (BMI &gt; 30). Among patients with serous tumors a significant (<jats:italic>p<\/jats:italic> = 0.01) worse survival was found in the subgroup of underweight (BMI &lt; 18.5) patients compared with patients in the other BMI groups. In multivariate analysis only FIGO\u2010stage and age were independent and significant prognostic factors. <jats:italic>Conclusion.<\/jats:italic> Overweight and obese patients did not have worse survival than normal weight and underweight patients. The prognostic impact of BMI on survival was only noted for underweight patients with serous tumors.<\/jats:p>","DOI":"10.3109\/00016340903322735","type":"journal-article","created":{"date-parts":[[2009,12,19]],"date-time":"2009-12-19T05:22:28Z","timestamp":1261200148000},"page":"101-107","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Body mass index as a prognostic factor in epithelial ovarian cancer and correlation with clinico\u2010pathological factors"],"prefix":"10.1111","volume":"89","author":[{"given":"INGIRIDUR","family":"SK\u00cdRNISD\u00d3TTIR","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BENGT","family":"SORBE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-1-73"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.01.061"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2005.07.123"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-05-0897"},{"key":"e_1_2_5_6_2","first-page":"1","volume-title":"Preventing and managing the global epidemic: Report of a WHO consultation on Obesity, Geneva, 3\u20105 June 1997","author":"World Health Organization (WHO) Consultation on Obesity","year":"1998"},{"key":"e_1_2_5_7_2","first-page":"822","article-title":"Body mass index, height, and the risk of ovarian cancer mortality in a prospective cohort of postmenopausal women","volume":"11","author":"Rodriquez C","year":"2002","journal-title":"Cancer Epidemiol, Biomarkers Prev"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021423"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-04-0519"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22194"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2007.06.010"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdm606"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.01013.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations","volume":"58","author":"Kaplan EL","year":"1958","journal-title":"Am Stat Assoc J"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djg010"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.03.005"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23509"},{"key":"e_1_2_5_18_2","first-page":"473","article-title":"Role of obesity in the surgical management of advanced\u2010stage ovarian cancer","volume":"49","author":"Wolfberg AJ","year":"2004","journal-title":"J Reprod Med"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13640-9"},{"key":"e_1_2_5_20_2","unstructured":"MunstedtK WagnerM KullmerU HackethalA FranckeFE.Cancer Causes Control;2008."},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)03590-X"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdg403"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016340903322735","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016340903322735","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T23:07:54Z","timestamp":1698707274000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016340903322735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.3109\/00016340903322735"],"URL":"https:\/\/doi.org\/10.3109\/00016340903322735","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1]]},"assertion":[{"value":"2010-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}