{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T16:10:37Z","timestamp":1780330237506,"version":"3.54.1"},"reference-count":33,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":183,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objectives<\/jats:italic>. To assess pregnant women's knowledge and understanding of first trimester prenatal screening (nuchal translucency, maternal serum free beta\u2010human chorionic gonadotrophin and pregnancy\u2010associated plasma\u2010protein\u2010A), to evaluate the impact of a new information booklet and investigate the effects of education and experiential knowledge of congenital disabilities on the perceived likelihood of accepting prenatal screening.<jats:italic>Design<\/jats:italic>. A quasi\u2010experimental quantitative study with a self\u2010completion questionnaire.<jats:italic>Setting.<\/jats:italic>Five different maternity care clinics in Iceland.<jats:italic>Population.<\/jats:italic>Expectant mothers in first trimester of pregnancy (<jats:italic>n<\/jats:italic>= 379).<jats:italic>Material and methods<\/jats:italic>. Expectant mothers were divided into two groups, an intervention and a control group, both receiving traditional care and information. The intervention group additionally received an information booklet about prenatal screening and diagnosis.<jats:italic>Main outcome measures.<\/jats:italic>Women's knowledge score of prenatal screening. The correlation between education, knowledge score, experiential knowledge of congenital disabilities, and the likelihood of accepting prenatal screening.<jats:italic>Results<\/jats:italic>. More than half of the women (57%) believed they received sufficient information to make an informed decision about screening. Knowledge scores were significantly higher for the intervention group (with mean 4.8 compared with 3.7 on a 0\u20138 scale,<jats:italic>p<\/jats:italic>&lt; 0.0001). Those with higher scores were more likely to accept screening (<jats:italic>p<\/jats:italic>&lt; 0.0001). Women with experiential knowledge of congenital anomalies in their own families were more likely to accept prenatal screening (<jats:italic>p<\/jats:italic>= 0.017).<jats:italic>Conclusions<\/jats:italic>. Various factors, e.g. experiential knowledge, education and information about prenatal screening affect the likelihood of participation in prenatal screening programs. More information results in better knowledge and higher uptake rate.<\/jats:p>","DOI":"10.3109\/00016341003686073","type":"journal-article","created":{"date-parts":[[2010,3,18]],"date-time":"2010-03-18T06:08:35Z","timestamp":1268892515000},"page":"931-938","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Effects of knowledge, education, and experience on acceptance of first trimester screening for chromosomal anomalies"],"prefix":"10.1111","volume":"89","author":[{"given":"VIGDIS","family":"STEFANSDOTTIR","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HEATHER","family":"SKIRTON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KRISTJAN","family":"JONASSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HILDUR","family":"HARDARDOTTIR","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JON JOHANNES","family":"JONSSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)91387-0"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3912\/OJIN.Vol5No03Man02","article-title":"Prenatal genetic screening","volume":"5","author":"Grant SS","year":"2000","journal-title":"Online J Issues Nurs"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(84)90530-1"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30119"},{"key":"e_1_2_6_6_2","first-page":"415","article-title":"Fetal nuchal translucency measurement at 11\u201313 weeks and risk assessment for fetal aneuploidy and cardiac anomalies","volume":"87","author":"Hardardottir H","year":"2001","journal-title":"Icelandic Med J"},{"key":"e_1_2_6_7_2","unstructured":"Foundation FM.Fetal Medicine Foundation.2009. 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