{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T06:56:07Z","timestamp":1699512967105},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,1,12]],"date-time":"2011-01-12T00:00:00Z","timestamp":1294790400000},"content-version":"vor","delay-in-days":14621,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1971,1]]},"abstract":"<jats:p>Invasive cervical carcinoma is the most commonly observed primary form of cancer in Korean females. This tumour constituted 37.6% of 1820 malignant tumours of known primary site encountered in a Korean surgical series at the Scandinavian\u2010sponsored National Medical Center in Seoul from December 1958 to August 1967. The age at diagnosis of invasive cervical cancer averaged 43.6 years, and the estimated population peak incidence was also within the fifth decade. Ninety\u2010five per cent of the cases were of the epidermoid type; the range of age among patients with adenocarcinoma was significantly greater than in those with epidermoid cancer. The age distribution of 1889 cases of simple chronic cervicitis, squamous\u2010cell dysplasia, intra\u2010epithelial neoplasia and invasive epidermoid carcinoma is presented and discussed. The observations in 1033 cases of progressive epithelial abnormalities are consistent with a linear regression of age at diagnosis on histological grade of epithelial alterations ranging from slight dysplasia to late invasive epidermoid cancer. Such an interrelation constitutes one among several circumstantial pieces of evidence that the morphological evolution of invasive epidermoid carcinoma passes through a spectrum of epithelial abnormalities. The present results support this concept of a step\u2010wise progression in epidermoid cervical carcinogenesis.<\/jats:p>","DOI":"10.3109\/00016347109157280","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T18:12:15Z","timestamp":1260295935000},"page":"17-24","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cancer of the Uterine Cervix in a Korean Biopsy Series: <i>With a Study of the Age Distribution in 1889 Cases of Chronic Cervicitis, Dysplasia, Intra\u2010epithelial and Invasive Epidermoid Carcinoma<\/i>"],"prefix":"10.1111","volume":"50","author":[{"given":"Per","family":"Wetteland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,12]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"Masseunders\u00f6kelser med henblikk p\u00e5 cancer cervicis uteri i \u00d6stfold fylke 1959\u20131965. Rapport I fra Landsforeningen mot Kreft","author":"Bjelke H.","year":"1969"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(56)90488-4"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196711)20:11<1899::AID-CNCR2820201116>3.0.CO;2-C"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)37837-1"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(49)90405-6"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1958.tb04890.x"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(49)90200-8"},{"key":"e_1_2_1_9_1","first-page":"800","article-title":"Primary adenocarcinoma of the cervix","volume":"63","author":"Hepler T. K.","year":"1952","journal-title":"Amer J Obstet Gynec"},{"key":"e_1_2_1_10_1","first-page":"86","volume-title":"Atlas of tumor pathology, Section IX, Fasc. 33","author":"Hertig A. T.","year":"1960"},{"key":"e_1_2_1_11_1","first-page":"1146","volume-title":"Pathology 5th ed.","author":"Hertig A. T.","year":"1966"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196402)17:2<213::AID-CNCR2820170211>3.0.CO;2-V"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016344609154462"},{"key":"e_1_2_1_14_1","first-page":"227","article-title":"Dix\u2010sept cas de cancer du col au stade 0 qui se sont transform\u00e9s en cancers vrais","volume":"5","author":"Karlstedt K.","year":"1954","journal-title":"Gynec Prat"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196711)20:11<1934::AID-CNCR2820201122>3.0.CO;2-4"},{"key":"e_1_2_1_16_1","volume-title":"Gynekologisk cancer: Klinik och terapi","author":"Kjellgren O.","year":"1967"},{"key":"e_1_2_1_17_1","volume-title":"Korea Annual 1967","year":"1967"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016345909153950"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1967)20:2<202::AID-CNCR2820200205>3.0.CO;2-Q"},{"key":"e_1_2_1_20_1","volume-title":"Cancer of the uterus: A statistical inquiry into the results of treatment, being an analysis of the existing literature","author":"Lane\u2010Claypon J. E.","year":"1927"},{"key":"e_1_2_1_21_1","first-page":"33","article-title":"Statistical and histopathological studies of malignant tumors among Koreans","volume":"16","author":"Lee C. K.","year":"1965","journal-title":"Seoul Univ J (C)"},{"key":"e_1_2_1_22_1","first-page":"73","article-title":"Malignant tumors among Koreans","volume":"9","author":"Lee C. K.","year":"1959","journal-title":"Seoul Univ J (C)"},{"key":"e_1_2_1_23_1","first-page":"2","article-title":"Clinical and pathological significance of anaplasia (atypical hyperplasia) of cervix uteri","volume":"13","author":"Mackay D. G.","year":"1959","journal-title":"Obstet Gynec"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1967)20:5<623::AID-CNCR2820200508>3.0.CO;2-J"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1967)20:1<86::AID-CNCR2820200113>3.0.CO;2-9"},{"key":"e_1_2_1_26_1","first-page":"88","volume-title":"Novak's gynecologic and obstetric pathology: With clinical and endocrine relations, 5th ed","author":"Novak E. R.","year":"1962"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.16.9.919"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(57)90057-1"},{"key":"e_1_2_1_29_1","first-page":"1290","article-title":"Surgical treatment of carcinoma of the cervix","volume":"63","author":"Peterson C. P.","year":"1952","journal-title":"Amer J Obstet Gynec"},{"key":"e_1_2_1_30_1","first-page":"87","volume-title":"Obstetrical and gynaecological pathology: For postgraduate students","author":"Rewell R. E.","year":"1960"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196603)19:3<395::AID-CNCR2820190313>3.0.CO;2-O"},{"key":"e_1_2_1_32_1","volume-title":"Cancer incidence in Sweden 1963. National Board of Health","author":"Ringertz N.","year":"1967"},{"key":"e_1_2_1_33_1","volume-title":"Pathology, 3rd ed","author":"Robbins S. L.","year":"1967"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196607)19:7<891::AID-CNCR2820190702>3.0.CO;2-Y"},{"key":"e_1_2_1_35_1","volume-title":"Statistical methods: Applied to experiments in agriculture and biology, 5th ed","author":"Snedecor G. W.","year":"1956"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196101\/02)14:1<153::AID-CNCR2820140119>3.0.CO;2-T"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1967)20:2<190::AID-CNCR2820200204>3.0.CO;2-T"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196404)17:4<508::AID-CNCR2820170412>3.0.CO;2-S"},{"issue":"412","key":"e_1_2_1_39_1","article-title":"Descriptive statistics on a nine\u2010year surgico\u2010pathological series from a Korean population: With particular reference to malignant tumours","author":"Wetteland P.","year":"1970","journal-title":"Acta Chir Scand"},{"key":"e_1_2_1_40_1","volume-title":"Pathology of tumours, 4th ed","author":"Willis R. A.","year":"1967"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(49)90197-0"},{"key":"e_1_2_1_42_1","first-page":"370","article-title":"A statistical study of tumors among Koreans","volume":"9","author":"Yun I. S.","year":"1949","journal-title":"Cancer Res"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016347109157280","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016347109157280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T19:32:45Z","timestamp":1699471965000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016347109157280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,1]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1971,1]]}},"alternative-id":["10.3109\/00016347109157280"],"URL":"https:\/\/doi.org\/10.3109\/00016347109157280","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1971,1]]},"assertion":[{"value":"2011-01-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}