{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T15:59:46Z","timestamp":1770134386545,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,1,12]],"date-time":"2011-01-12T00:00:00Z","timestamp":1294790400000},"content-version":"vor","delay-in-days":12429,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1977,1]]},"abstract":"<jats:p><jats:bold>Abstract. <\/jats:bold> Fifty\u2010six patients, chosen by random sampling from a total group of 120 post\u2010term women, received dex\u2010amethasone (Decadron\u00ae, \u201cMSD\u201d) 2 mg 3 times a day for 4 days, the other 64 patients acting as controls.<\/jats:p><jats:p>The evolution of uterine activity was evaluated using pelvic score (PS) and a modified low dosage oxytocin sensitivity test (OST) before (T<jats:sub>1<\/jats:sub>) and after (T<jats:sub>2<\/jats:sub>) the treatment.<\/jats:p><jats:p>During the interval from the second to the 6th day inclusive after T<jats:sub>1<\/jats:sub> 35 women of the dexamethasone group and 15 of the control group had a spontaneous onset of labour (SO) (0.001&lt;<jats:italic>P<\/jats:italic>&lt;0.01).<\/jats:p><jats:p>Five patients in the dexamethasone group with primary rupture of membranes started labour spontaneously within 12 hours after membrane rupture, 7 patients in the control group with primary rupture of membranes received oxytocin as labour did not start within 24 hours.<\/jats:p><jats:p>Excluding patients artificially induced, the mean interval from T<jats:sub>1<\/jats:sub> to SO was 6.8 days in the control group and 5.2 days in the dexamethasone group (P&lt;0.001).<\/jats:p><jats:p>In both groups PS and the sum of Montevideo units (MU) during OST increased from T<jats:sub>1<\/jats:sub> to T<jats:sub>2<\/jats:sub>, the increase was significantly greater in the dexamethasone group than in the control group. We found no correlation between the results of OST and the T<jats:sub>1<\/jats:sub>\u2010SO interval. Dexamethasone, as used in this study, may promote labour in prolonged human pregnancy. Due to its low potency, it is not a substitute for oxytocin in the induction of labour.<\/jats:p><jats:p>The lowered placento\u2010fetal quotient in the dexamethasone group warrants further study of the effects of steroid hormone on placental function.<\/jats:p>","DOI":"10.3109\/00016347709155013","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T18:05:49Z","timestamp":1260295549000},"page":"467-473","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The Effect of Dexamethasone Therapy in Prolonged Pregnancy"],"prefix":"10.1111","volume":"56","author":[{"given":"Helge","family":"Jenssen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per Bernhard","family":"Wright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,12]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"266","article-title":"Pelvic scoring for elective induction","volume":"24","author":"Bishop E. 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