{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T21:58:03Z","timestamp":1757455083979},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,1,12]],"date-time":"2011-01-12T00:00:00Z","timestamp":1294790400000},"content-version":"vor","delay-in-days":12064,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1978,1]]},"abstract":"<jats:p><jats:bold>Abstract. <\/jats:bold> A woman suffering from Cushing's disease from the age of 17 who had been treated consecutively with pituitary irradiation, bilateral partial adrenalectomy and o, p'\u2010DDD (Mitotane, USP) presented the clinical picture of Nelson's syndrome (hypoadrenalism with secondary hypersecretion of ACTH and MSH) at the age of 32. Under substitution therapy with corticoids she became pregnant for the first time at the age of 38. The course of the pregnancy was normal and at term she was delivered of a normal child by Cesarean section. The materno\u2010fetal relationship, the increased risk of pituitary infarction during pregnancy and the possible teratogenic effect of chemotherapy in such cases are discussed.<\/jats:p>","DOI":"10.3109\/00016347809154034","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T18:05:02Z","timestamp":1260295502000},"page":"373-375","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Pregnancy in a case of nelson's syndrome"],"prefix":"10.1111","volume":"57","author":[{"given":"Sara","family":"Leiba","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiuta","family":"Kaufman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gideon","family":"Winkelsberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles M.","family":"Bahary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-37-2-230"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(72)80547-X"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5988.87"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107515"},{"issue":"130","key":"e_1_2_1_6_1","first-page":"7","article-title":"The foetal adrenal cortex in the human","author":"Johannisson E.","year":"1968","journal-title":"Acta Endocrin (Kbn)"},{"key":"e_1_2_1_7_1","first-page":"117","article-title":"Detailed hormonal studies during and after pregnancy in a previously hypophysectomised patient","volume":"73","author":"J\u00f8rgensen P. I.","year":"1973","journal-title":"Acta Endocr (Kbv)"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/0002-9378(72)90677-1","article-title":"The effect of adrenocorticotropic hormone and dexamethasone administered to the fetus in utero, upon maternal and fetal estrogens","volume":"113","author":"Kiyoshi A.","year":"1972","journal-title":"Am J Obst Gynec"},{"key":"e_1_2_1_9_1","first-page":"351","article-title":"Gu\u00e9rison ou r\u00e9mission de la maladie de Cushing par usage therapeutique prolong\u00e9e dC o, p'\u2010DDD","volume":"34","author":"Luton J. P.","year":"1973","journal-title":"Ann Endocr (Paris)"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-93-1-115"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(74)90287-7"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016347809154034","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016347809154034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T15:41:28Z","timestamp":1699458088000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016347809154034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,1]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1978,1]]}},"alternative-id":["10.3109\/00016347809154034"],"URL":"https:\/\/doi.org\/10.3109\/00016347809154034","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,1]]},"assertion":[{"value":"2011-01-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}