{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T17:51:23Z","timestamp":1757699483269},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":11698,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1979,1]]},"abstract":"<jats:p><jats:bold>Abstract. <\/jats:bold> 139 samples of amniotic fluid from diabetic women collected during 34\u201039 weeks of pregnancy showed higher levels of lecithin, phosphatidylinositol (PI) and phosphatidylglycerol (PG) indicating an accelerated surfactant synthesis as compared to that observed in normal pregnancies (13). In ten infants with respiratory distress syndrome (RDS) delivered from diabetic mothers the lecithin\/sphingomyelin (L\/S), PI\/S and PG\/S ratios were generally low. Only four samples showed definitely immature L\/S ratios, whereas the amniotic fluid content of PG in all samples was unmeasurable or low.<\/jats:p><jats:p>In 56 samples of amniotic fluid collected during the third trimester from preeclamptic pregnancies PI\/S and PG\/S ratios after 36\u201037 weeks were comparable with those of normal pregnancies. In 11 neonates with subsequent RDS the L\/S ratios were immature, and PG was critically low or lacking in the majority of the samples.<\/jats:p><jats:p>No convincing association between the PI content and development of RDS could be observed in any of the groups.<\/jats:p>","DOI":"10.3109\/00016347909154062","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T18:04:06Z","timestamp":1260295446000},"page":"433-438","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["AMNIOTIC FLUID PHOSPHATIDYLINOSITOL AND PHOSPHATIDYLGLYCEROL"],"prefix":"10.1111","volume":"58","author":[{"given":"Julie","family":"Skjaeraasen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Stray\u2010Pedersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1973.tb08137.x"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(73)80472-X"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/0002-9378(73)90404-3","article-title":"Lecithin\/sphingomyelin ratios in normal and abnormal pregnancy","volume":"115","author":"Cluck L.","year":"1973","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(76)90782-1"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-197706000-00003"},{"key":"e_1_2_1_7_1","unstructured":"HallmanM. KankareP..Respiratory distress syndrome (RDS) in offsprings of diabetic mothers due to the failure of surfactant phosphatidylglycerol (PG) induction. Abstract of 6th Nordic Congress of Perinatal Medicine Oulu Sept. 1977."},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","volume-title":"Outcome of pregnancies in diabetic mothers in Norway 1967\u20131976","author":"Jervell J.","DOI":"10.1007\/BF00290489"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016347409162160"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2760(74)90179-9"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016347609156918"},{"key":"e_1_2_1_12_1","unstructured":"Skj\u00e6aasenJ. Stray\u2010PedersenS..Phosphatidylinositol and phosphatidylglycerol in normal and in diabetic women. Abstract 6th Nordic Congress of Perinatal Medicine Oulu Sept. 1977."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016347909154581"},{"key":"e_1_2_1_14_1","article-title":"Amniotic fluid phosphatidylinositol and phosphatidylglycerol. I.: Normal pregnancies","author":"Skj\u00e6raasen J.","journal-title":"Acta Obstet Gynecol Scand"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)32384-7"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016347909154062","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016347909154062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T09:14:36Z","timestamp":1699434876000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016347909154062"}},"subtitle":["II. diabetic and preeclamptic pregnancies"],"short-title":[],"issued":{"date-parts":[[1979,1]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1979,1]]}},"alternative-id":["10.3109\/00016347909154062"],"URL":"https:\/\/doi.org\/10.3109\/00016347909154062","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,1]]},"assertion":[{"value":"2011-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}