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reliable contraceptive, but also a very potent drug for the treatment of both acne and seborrhea, and of milder cases of hirsutism. the effect of Diane<jats:sup>\u00ae<\/jats:sup> on markedly increased hair growth was not so pronounced. in addition to the presentation of the most pertinent steps of the clinical investigation of Diane<jats:sup>\u00ae<\/jats:sup>, the possible mode of actions of antiandrogens alone and in combination with an estrogen is discussed.<\/jats:p>","DOI":"10.3109\/00016347909157227","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T18:03:45Z","timestamp":1260295425000},"page":"33-42","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["THE DEVELOPMENT AND EVALUATION OF AN OVULATION INHIBITOR (DIANE\u00ae) CONTAINING AN 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