{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T06:56:22Z","timestamp":1699512982624},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":11333,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[1980,1]]},"abstract":"<jats:p>Of 17 patients with longstanding (3\u201315 years, mean 7.7 years) amenorrhea and hyperprolactinemia, 8 developed their amenorrhea after the use of oral contraceptives (Group I) and 9 became amenorrhoic spontaneously (Group II). There were no differences between the groups with respect ot the basal serum levels of FSH, LH, low polar estrogens (estradiol\u201017\u03b2 + estrone) and prolactin. Tomography revealed pituitary adenoma in four patients. One of these developed symptoms of her tumor during pregnancy; the symptoms disappeared after delivery. The other patients with tumors are checked twice a year and have not yet received any treatment. The patients with no detectable tumors were treated with bromocriptine starting with 1.25 \u00d7 3 daily. The peripheral serum levels of prolactin, FSH, LH, low polar estrogens and progesterone were determined once a week and if the prolactin levels remained high, the bromocriptine dose was increased. All these patients started to menstruate as soon as prolactin returned to normal levels (below 25 \u03bcmg\/l). All patients who wished to became pregnant, <jats:italic>i. e.<\/jats:italic> 6 patients. Three were delivered by cesarean section, one had a normal delivery and two are still pregnant.<\/jats:p><jats:p>There was no difference between Group I and Group II in the dose required or in the duration of treatment before menstruation started. Three cases of galactorrhea were found.<\/jats:p>","DOI":"10.3109\/00016348009154630","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T18:03:16Z","timestamp":1260295396000},"page":"137-141","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hyperprolactinemia in Cases of Infertility and Amenorrhea"],"prefix":"10.1111","volume":"59","author":[{"given":"Mirjam","family":"Furuhjelm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thure","family":"Rydner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kjell","family":"Carlstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"435","article-title":"Bromocriptine treatment of 42 hyperprolactinemic women with secondary amenorrhea","volume":"88","author":"Berg T.","year":"1978","journal-title":"Acta Encocrinol (Kbh)"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5828.669"},{"key":"e_1_2_1_4_1","first-page":"716","article-title":"Radioimmunoassay of oestrone and oestradiol\u201017\u03b2 in human and bovine peripheral plasma","volume":"71","author":"Edqvist L.\u2010E.","year":"1972","journal-title":"Acta Endocrinol (Kbh)"},{"key":"e_1_2_1_5_1","unstructured":"FriesenH. TollisG. ShrillJ. C. HwangP.(1977)Studies on human prolactin chemistry radioreceptor assay and clinical significance. Proceedings of the international symposium on human prolactin in Brussels. June 1977 H.Prolachi.Elsevier New York 11."},{"key":"e_1_2_1_6_1","first-page":"42","volume-title":"Sexual behaviour and contraception in adolescence","author":"Furuhjelm M.","year":"1975"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/194495a0"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.68.8.1902"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1186\/BF03547446","article-title":"Preparation of proteinsteroid conjugates and antisera against oestradiol\u201017\u03b2","volume":"14","author":"Martinsson K.","year":"1973","journal-title":"Acta Vet Scand"},{"key":"e_1_2_1_10_1","unstructured":"RobynC. DelvoyeP. BadawiM. DesnoeckDelongne K. J. CaufriezA. Martin\u2010PerezG. Lopez de CampoG. L'HermiteM..Introduction to the physiology of human prolactin. Acta Endocrinologica Congress Lausanne 1977."},{"key":"e_1_2_1_11_1","unstructured":"ScheiderH. P. G. BohnetH. G. MuehlenstedtD..Prolactin in female fertility. Acta Endocrinologica Congress Lausanne 1977;17 Abstract."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-7824(72)90024-8"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.3109%2F00016348009154630","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.3109\/00016348009154630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T12:06:23Z","timestamp":1699445183000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.3109\/00016348009154630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,1]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1980,1]]}},"alternative-id":["10.3109\/00016348009154630"],"URL":"https:\/\/doi.org\/10.3109\/00016348009154630","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,1]]},"assertion":[{"value":"2011-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}